(Q46348798)

21 December 2017

title

High glucose activates PKC-zeta and NADPH oxidase through autocrine TGF-beta1 signaling in mesangial cells (English)

1 reference

21 December 2017

1 reference

7

Catharine I Whiteside

0 references

author name string

Ling Xia

1

1 reference

21 December 2017

Hong Wang

2

1 reference

21 December 2017

Snezana Munk

3

1 reference

21 December 2017

Janice Kwan

4

1 reference

21 December 2017

Howard J Goldberg

5

1 reference

21 December 2017

I George Fantus

6

1 reference

21 December 2017

publication date

24 September 2008

1 reference

21 December 2017

American Journal of Physiology - Renal Physiology

published in

1 reference

21 December 2017

volume

295

1 reference

21 December 2017

issue

6

1 reference

21 December 2017

page(s)

F1705-14

1 reference

21 December 2017

Effects of NADPH oxidase inhibitor in diabetic nephropathy

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

NAD(P)H oxidases and TGF-beta-induced cardiac fibroblast differentiation: Nox-4 gets Smad

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

The early natural history of nephropathy in type 1 diabetes: II. Early renal structural changes in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Redox signalling involving NADPH oxidase-derived reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Phosphatidylinositol 3-kinase gamma signaling through protein kinase Czeta induces NADPH oxidase-mediated oxidant generation and NF-kappaB activation in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Mice lacking Smad3 are protected against streptozotocin-induced diabetic glomerulopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Tyrosine phosphorylation-dependent PI 3 kinase/Akt signal transduction regulates TGFbeta-induced fibronectin expression in mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Amino acids as modulators of endothelium-derived nitric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

MAPK/AP-1-dependent regulation of PAI-1 gene expression by TGF-beta in rat mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Overview of Glucose Signaling in Mesangial Cells in Diabetic Nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

High ambient glucose enhances sensitivity to TGF-beta1 via extracellular signal--regulated kinase and protein kinase Cdelta activities in human mesangial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Translocation of Glomerular p47phox and p67phox by Protein Kinase C-β Activation Is Required for Oxidative Stress in Diabetic Nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

In high glucose protein kinase C-zeta activation is required for mesangial cell generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

The signaling network of transforming growth factor beta1, protein kinase Cdelta, and integrin underlies the spreading and invasiveness of gastric carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Role of TGF-beta signaling in extracellular matrix production under high glucose conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

The involvement of advanced glycation endproducts (AGEs) in renal injury of diabetic glomerulosclerosis: association with phenotypic change in renal cells and infiltration of immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Regulation of protein kinase C delta by phorbol ester, endothelin-1, and platelet-derived growth factor in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Extracellular matrix metabolism in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Involvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Activation of protein kinase Czeta mediates luteinizing hormone- or forskolin-induced NGFI-B expression in preovulatory granulosa cells of rat ovary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Glucose stimulation of transforming growth factor-beta bioactivity in mesangial cells is mediated by thrombospondin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

TGF-beta signal transduction and mesangial cell fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Activation of phosphoinositide 3-kinase in response to high glucose leads to regulation of reactive oxygen species-related nuclear factor-kappaB activation and cyclooxygenase-2 expression in mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

N-acetyl-seryl-aspartyl-lysyl-proline prevents renal insufficiency and mesangial matrix expansion in diabetic db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Insulin and PIP3 activate PKC-zeta by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Transforming growth factor beta signaling via Ras in mesenchymal cells requires p21-activated kinase 2 for extracellular signal-regulated kinase-dependent transcriptional responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Involvement of HB-EGF and EGF receptor transactivation in TGF-beta-mediated fibronectin expression in mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Glomerular expression of platelet-derived growth factor (PDGF)-A, -B chain and PDGF receptor-alpha, -beta in human diabetic nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Glomerular expression of thrombospondin-1, transforming growth factor beta and connective tissue growth factor at different stages of diabetic nephropathy and their interdependent roles in mesangial response to diabetic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

TGF-beta induced hyaluronan synthesis in orbital fibroblasts involves protein kinase C betaII activation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Phosphoinositide 3-kinase in disease: timing, location, and scaffolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Mesangial cell NADPH oxidase upregulation in high glucose is protein kinase C dependent and required for collagen IV expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Regulation of transforming growth factor beta in diabetic nephropathy: implications for treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Mediators of diabetic renal disease: the case for tgf-Beta as the major mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00043.2008

10.1152/AJPRENAL.00043.2008

21 January 2018

Identifiers

DOI

1 reference

21 December 2017

PubMed ID

18815221

1 reference

21 December 2017