(Q46387376)

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Lesion-targeted thrombopoietin potentiates vasculogenesis by enhancing motility and enlivenment of transplanted endothelial progenitor cells via activation of Akt/mTOR/p70S6kinase signaling pathway

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18773906

Lesion-targeted thrombopoietin potentiates vasculogenesis by enhancing motility and enlivenment of transplanted endothelial progenitor cells via activation of Akt/mTOR/p70S6kinase signaling pathway (English)

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18773906

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Takayuki Asahara

8

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Takayuki Asahara

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Europe PubMed Central

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21 December 2017

http://europepmc.org/abstract/MED/18773906

author name string

Masamichi Eguchi

1

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21 December 2017

http://europepmc.org/abstract/MED/18773906

Haruchika Masuda

2

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21 December 2017

http://europepmc.org/abstract/MED/18773906

Sangmon Kwon

3

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21 December 2017

http://europepmc.org/abstract/MED/18773906

Katsuya Shirakura

4

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21 December 2017

http://europepmc.org/abstract/MED/18773906

Tomoko Shizuno

5

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21 December 2017

http://europepmc.org/abstract/MED/18773906

Rie Ito

6

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21 December 2017

http://europepmc.org/abstract/MED/18773906

Michiru Kobori

7

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21 December 2017

http://europepmc.org/abstract/MED/18773906

publication date

16 August 2008

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21 December 2017

http://europepmc.org/abstract/MED/18773906

Journal of Molecular and Cellular Cardiology

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21 December 2017

http://europepmc.org/abstract/MED/18773906

45

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21 December 2017

http://europepmc.org/abstract/MED/18773906

5

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21 December 2017

http://europepmc.org/abstract/MED/18773906

661-669

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PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18773906

Isolation of putative progenitor endothelial cells for angiogenesis

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CD34-positive cells exhibit increased potency and safety for therapeutic neovascularization after myocardial infarction compared with total mononuclear cells

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Circulating endothelial progenitor cells, vascular function, and cardiovascular risk

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Erythropoietin promotes endothelial progenitor cell proliferative and adhesive properties in a PI 3-kinase-dependent manner

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Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization

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Functional isolation and characterization of human hematopoietic stem cells

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Thrombopoietin and the hematopoietic stem cell

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Activation of cyclic AMP pathway prevents CD34(+) cell apoptosis

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Thrombopoietin contributes to enhanced platelet activation in patients with unstable angina

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High serum erythropoietin level is associated with smaller infarct size in patients with acute myocardial infarction who undergo successful primary percutaneous coronary intervention

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Endogenous G-CSF and CD34+ cell mobilization after acute myocardial infarction

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Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKCzeta or mTOR in TPO-dependent cell lines and primary megakaryocytes.

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HMG-CoA reductase inhibitor mobilizes bone marrow--derived endothelial progenitor cells

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Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2

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Thrombopoietin Stimulates Endothelial Cell Motility and Neoangiogenesis by a Platelet-Activating Factor–Dependent Mechanism

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7 January 2021

Rapamycin inhibits proliferation and differentiation of human endothelial progenitor cells in vitro

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VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells

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Characterization of two types of endothelial progenitor cells and their different contributions to neovasculogenesis.

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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

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Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects

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7 January 2021

Erythropoietin regulates endothelial progenitor cells

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Estrogen reduces endothelial progenitor cell senescence through augmentation of telomerase activity

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Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

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Upstream and downstream of mTOR

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Phosphoinositide 3-kinase signalling pathways in tumor progression, invasion and angiogenesis.

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Restraining PI3K: mTOR signalling goes back to the membrane.

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In Human Endothelial Cells Amino Acids Inhibit Insulin-induced Akt and ERK1/2 Phosphorylation by an mTOR-dependent Mechanism

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Thrombopoietin gene transfer-mediated enhancement of angiogenic responses to acute ischemia

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Effects of pulmonary ischemia-reperfusion on platelet adhesion in subpleural arterioles in rabbits.

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Thrombocytes are the major source for soluble vascular endothelial growth factor in peripheral blood

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Elevation of Vascular Endothelial Growth Factor-A Serum Levels Following Acute Myocardial Infarction. Evidence for its Origin and Functional Significance

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Platelet-released phospholipids link haemostasis and angiogenesis

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Platelet microparticles induce angiogenesis in vitro

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Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor

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Platelet-activating factor (PAF) induces corneal neovascularization and upregulates VEGF expression in endothelial cells

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Thrombopoietin stimulates migration and activates multiple signaling pathways in hepatoblastoma cells.

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A phase I trial of recombinant human thrombopoietin in patients with delayed platelet recovery after hematopoietic stem cell transplantation

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Recombinant human thrombopoietin augments mobilization of peripheral blood progenitor cells for autologous transplantation.

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Identifiers

10.1016/J.YJMCC.2008.08.002

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18773906

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/18773906

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