(Q46412617)

English

Two populations of p27 use differential kinetics to phosphorylate Ser-10 and Thr-187 via phosphatidylinositol 3-Kinase in response to fibroblast growth factor-2 stimulation

scientific article published on 5 January 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

Two populations of p27 use differential kinetics to phosphorylate Ser-10 and Thr-187 via phosphatidylinositol 3-Kinase in response to fibroblast growth factor-2 stimulation (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

phosphorylation

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author name string

Jeong Goo Lee

1

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

Eunduck P Kay

2

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

language of work or name

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publication date

5 January 2007

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

282

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

9

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

6444-6454

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

Regulatory role of PI 3-kinase on expression of Cdk4 and p27, nuclear localization of Cdk4, and phosphorylation of p27 in corneal endothelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

FGF-2 induced by interleukin-1 beta through the action of phosphatidylinositol 3-kinase mediates endothelial mesenchymal transformation in corneal endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Regulatory role of FGF-2 on type I collagen expression during endothelial mesenchymal transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Phosphatidylinositol 3-kinases in tumor progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Cross-talk among Rho GTPases acting downstream of PI 3-kinase induces mesenchymal transformation of corneal endothelial cells mediated by FGF-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Subcellular localization of procollagen I and prolyl 4-hydroxylase in corneal endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

FGF-2-induced wound healing in corneal endothelial cells requires Cdc42 activation and Rho inactivation through the phosphatidylinositol 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Histone H1 phosphorylation by Cdk2 selectively modulates mouse mammary tumor virus transcription through chromatin remodeling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Nuclear accumulation of cyclin E/Cdk2 triggers a concentration-dependent switch for the destruction of p27Xic1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607808200

21 January 2018

Identifiers

10.1074/JBC.M607808200

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/17209046

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