(Q46419852)

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Knock-in mice lacking the PDZ-ligand motif of mGluR7a show impaired PKC-dependent autoinhibition of glutamate release, spatial working memory deficits, and increased susceptibility to pentylenetetrazol.

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12 January 2020

Knock-in mice lacking the PDZ-ligand motif of mGluR7a show impaired PKC-dependent autoinhibition of glutamate release, spatial working memory deficits, and increased susceptibility to pentylenetetrazol (English)

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12 January 2020

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Volker Eulenburg

3

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12 January 2020

Volker Eulenburg

4

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12 January 2020

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Heinrich Betz

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12 January 2020

Mireille Lerner-Natoli

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Mireille Lerner-Natoli

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12 January 2020

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Chuan-Sheng Zhang

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12 January 2020

Federica Bertaso

2

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12 January 2020

Greta Ann Herin

6

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12 January 2020

Liane Bauer

7

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12 January 2020

Joel Bockaert

8

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12 January 2020

Laurent Fagni

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12 January 2020

Astrid Scheschonka

11

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12 January 2020

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1 August 2008

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12 January 2020

Journal of Neuroscience

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12 January 2020

28

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12 January 2020

34

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12 January 2020

8604-8614

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12 January 2020

(R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term depression in hippocampal interneurons: joint requirement for pre- and postsynaptic events

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calmodulin dependence of presynaptic metabotropic glutamate receptor signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PICK1 interacts with and regulates PKC phosphorylation of mGLUR7

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective blockade of P/Q-type calcium channels by the metabotropic glutamate receptor type 7 involves a phospholipase C pathway in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of the C-terminal tail region of the metabotropic glutamate receptor 7 with the protein kinase C substrate PICK1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic clustering of mGluR7a requires the PICK1 PDZ domain binding site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants for PICK1 synaptic aggregation and mGluR7a receptor coclustering: role of the PDZ, coiled-coil, and acidic domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDZ domains: structural modules for protein complex assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of glutamate release by metabotropic glutamate receptor 7 affects both [Ca2+]c and cAMP: evidence for a strong reduction of Ca2+ entry in single nerve terminals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G-protein-coupled receptors for neurotransmitter amino acids: C-terminal tails, crowded signalosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PICK1 is required for the control of synaptic transmission by the metabotropic glutamate receptor 7

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different binding motifs in metabotropic glutamate receptor type 7b for filamin A, protein phosphatase 1C, protein interacting with protein kinase C (PICK) 1 and syntenin allow the formation of multimeric protein complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of excitatory postsynaptic responses by persistently active metabotropic glutamate receptors in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of the metabotropic glutamate receptor subtype 7 selectively impairs short-term working memory but not long-term memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Making protein interactions druggable: targeting PDZ domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mGluR7 is a metaplastic switch controlling bidirectional plasticity of feedforward inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pias1 interaction and sumoylation of metabotropic glutamate receptor 8

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonists and antagonists for group III metabotropic glutamate receptors 6, 7 and 8.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered seizure susceptibility in mice lacking the Ca(v)2.3 E-type Ca2+ channel.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MacMARCKS interacts with the metabotropic glutamate receptor type 7 and modulates G protein-mediated constitutive inhibition of calcium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperekplexia phenotype of glycine receptor alpha1 subunit mutant mice identifies Zn(2+) as an essential endogenous modulator of glycinergic neurotransmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sumoylation in neurons: nuclear and synaptic roles?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholine and phorbol esters inhibit potassium currents evoked by adenosine and cAMP in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of excitatory amino acid antagonists on evoked and spontaneous excitatory potentials in guinea-pig hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycinergic synapses in the rod pathway of the rat retina: cone bipolar cells express the alpha 1 subunit of the glycine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional and developmental profile of modulation of hippocampal synaptic transmission and LTP by AP4-sensitive mGluRs in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compartmental localization of a metabotropic glutamate receptor (mGluR7): two different active sites at a retinal synapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic localization of a metabotropic glutamate receptor, mGluR7, in the primary afferent neurons: an immunohistochemical study in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit interactions in the assembly of neuronal Kir3.0 inwardly rectifying K+ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization of metabotropic glutamate receptors, mGluR7a and mGluR7b, in the central nervous system of the adult rat and mouse: a light and electron microscopic study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18716219

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0628-08.2008

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18716219%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18716219%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18716219%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

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