(Q46426860)

2 July 2019

title

GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis (English)

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2 July 2019

amyotrophic lateral sclerosis

main subject

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author

Florian Muller

3

1 reference

http://europepmc.org/abstract/MED/18706911

22 December 2017

Holly Van Remmen

7

object named as

Holly Van Remmen

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2 July 2019

9

Arlan Richardson

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2 July 2019

author name string

Anson Pierce

1

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2 July 2019

Hamid Mirzaei

2

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2 July 2019

Eric De Waal

4

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2 July 2019

Alexander B Taylor

5

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2 July 2019

Shanique Leonard

6

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2 July 2019

Fred Regnier

8

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2 July 2019

Asish Chaudhuri

10

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2 July 2019

language of work or name

English

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publication date

6 August 2008

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2 July 2019

Journal of Molecular Biology

published in

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2 July 2019

volume

382

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2 July 2019

issue

5

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2 July 2019

page(s)

1195-1210

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2 July 2019

describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6348903/fullTextXML

inferred from PubMed Central ID database lookup

cites work

New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase.

1 reference

12 December 2020

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

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Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1.

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Protein oxidation in aging and age-related diseases

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Reduced creatine kinase activity in transgenic amyotrophic lateral sclerosis mice

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Protein turnover by the proteasome in aging and disease.

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Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site

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Selective degradation of oxidatively modified protein substrates by the proteasome.

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12 December 2020

Oxidation of glyceraldehyde-3-phosphate dehydrogenase enhances its binding to nucleic acids

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12 December 2020

Ascorbate-induced oxidation of glyceraldehyde-3-phosphate dehydrogenase

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Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature

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12 December 2020

Transfer reactions of acetyl phosphate catalyzed by glyceraldehyde-3-phosphate dehydrogenase

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12 December 2020

The action of glyceraldehyde-3-phosphate dehydrogenase on reduced diphosphopyridine nucleotide

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12 December 2020

Inactivation of Rabbit Muscle Creatine Kinase by Hydrogen Peroxide

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12 December 2020

Creatine and creatine kinase measurement

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12 December 2020

A 'molecular switchboard'--covalent modifications to proteins and their impact on transcription

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12 December 2020

Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders.

1 reference

12 December 2020

The SufE sulfur-acceptor protein contains a conserved core structure that mediates interdomain interactions in a variety of redox protein complexes

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12 December 2020

Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis

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12 December 2020

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

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12 December 2020

Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis

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12 December 2020

A novel approach for screening the proteome for changes in protein conformation

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12 December 2020

High-resolution structure of human D-glyceraldehyde-3-phosphate dehydrogenase

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12 December 2020

Identification of rotenone-induced modifications in alpha-synuclein using affinity pull-down and tandem mass spectrometry.

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Oxidative stress and antioxidant enzyme upregulation in SOD1-G93A mouse skeletal muscle.

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12 December 2020

Measurement of multisite oxidation kinetics reveals an active site conformational change in Spo0F as a result of protein oxidation

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12 December 2020

Failure of protein quality control in amyotrophic lateral sclerosis

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12 December 2020

Detection of protein carbonyls in aging liver tissue: A fluorescence-based proteomic approach

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12 December 2020

Extent of Modifications in Human Proteome Samples and Their Effect on Dynamic Range of Analysis in Shotgun Proteomics

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12 December 2020

On the relation of oxidative stress to neuroinflammation: lessons learned from the G93A-SOD1 mouse model of amyotrophic lateral sclerosis

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12 December 2020

Protein oxidation and aging

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12 December 2020

Protein oxidation and degradation during aging: role in skin aging and neurodegeneration

1 reference

12 December 2020

Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability

1 reference

12 December 2020

Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production

1 reference

12 December 2020

The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death

1 reference

12 December 2020

Oxidation and structural perturbation of redox-sensitive enzymes in injured skeletal muscle

1 reference

12 December 2020

Metal-catalyzed oxidation of human serum albumin: conformational and functional changes. Implications in protein aging

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12 December 2020

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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12 December 2020

Oxidative modification of glutamine synthetase. I. Inactivation is due to loss of one histidine residue

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Bis(1,8-anilinonaphthalenesulfonate). A novel and potent inhibitor of microtubule assembly.

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Exposure of hydrophobic moieties promotes the selective degradation of hydrogen peroxide-modified hemoglobin by the multicatalytic proteinase complex, proteasome

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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12 December 2020

Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions

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12 December 2020

Interactive intermediates are formed during the urea unfolding of rhodanese

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12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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12 December 2020

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Glyceraldehyde-3-phosphate dehydrogenase is over-expressed during apoptotic death of neuronal cultures and is recognized by a monoclonal antibody against amyloid plaques from Alzheimer's brain

1 reference

12 December 2020

Modification of protein surface hydrophobicity and methionine oxidation by oxidative systems

1 reference

12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

12 December 2020

Photoincorporation of fluorescent probe into GroEL: defining site of interaction

1 reference

12 December 2020

10.1016/J.JMB.2008.07.088

Identifiers

DOI

1 reference

2 July 2019

PMCID

6348903

1 reference

2 July 2019

PubMed ID

18706911

1 reference

2 July 2019