(Q46428813)

22 December 2017

title

Metabotropic glutamate receptors 5 blockade reverses spatial memory deficits in a mouse model of Parkinson's disease (English)

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22 December 2017

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1

Elvira De Leonibus

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22 December 2017

Francesca Managò

2

Francesca Managò

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22 December 2017

Francesco Giordani

3

Francesco Giordani

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22 December 2017

Francesco Petrosino

4

Francesco Petrosino

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22 December 2017

Sebastien Lopez

5

Sebastien Lopez

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22 December 2017

Alberto Oliverio

6

Alberto Oliverio

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22 December 2017

Marianne Amalric

7

Marianne Amalric

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22 December 2017

Andrea Mele

8

Andrea Mele

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22 December 2017

language of work or name

English

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publication date

13 August 2008

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22 December 2017

published in

Neuropsychopharmacology

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22 December 2017

volume

34

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22 December 2017

issue

3

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22 December 2017

page(s)

729-738

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22 December 2017

The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

A temporally distinct role for group I and group II metabotropic glutamate receptors in object recognition memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Striatal dopamine and learning strategy-an (123)I-FP-CIT SPECT study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates PCP-induced cognitive deficits in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Simultaneous blockade of adenosine A2A and metabotropic glutamate mGlu5 receptors increase their efficacy in reversing Parkinsonian deficits in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

L-DOPA disrupts activity in the nucleus accumbens during reversal learning in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Dopaminergic modulation of high-level cognition in Parkinson's disease: the role of the prefrontal cortex revealed by PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Spatial deficits in a mouse model of Parkinson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Chronic treatment with the mGlu5R antagonist MPEP reduces the functional effects of the mGlu5R agonist CHPG in the striatum of 6-hydroxydopamine-lesioned rats: possible relevance to the effects of mGlu5R blockade in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Visuospatial ability of parkinsonians and elderly adults in location memory tasks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Neuroprotective action of MPEP, a selective mGluR5 antagonist, in methamphetamine-induced dopaminergic neurotoxicity is associated with a decrease in dopamine outflow and inhibition of hyperthermia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Effects of mGlu1 and mGlu5 receptor antagonists on negatively reinforced learning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

N-Methyl-d-Aspartate Antagonists in the Treatment of Parkinson's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Corticostriatal LTP requires combined mGluR1 and mGluR5 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Study of CA1 place cell activity and exploratory behavior following spatial and nonspatial changes in the environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Impaired learning in a spatial working memory version and in a cued version of the water maze in rats with MPTP-induced mesencephalic dopaminergic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Spatial learning in rats is impaired after degeneration of the nigrostriatal dopaminergic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: relevance for learning and memory formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

The role of striatal metabotropic glutamate receptors in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Blockade of the metabotropic glutamate receptor subtype 5 (mGluR5) produces antiparkinsonian-like effects in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Dysfunction of the cortico-basal ganglia-cortical loop in a rat model of early parkinsonism is reversed by metabotropic glutamate receptor 5 antagonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Abnormal basal ganglia outflow in Parkinson's disease identified with PET. Implications for higher cortical functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Spatial and non-spatial working memory at different stages of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Modulation of dopaminergic and glutamatergic brain function: PET studies on parkinsonian rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Differential effects of mGluR1 and mGlur5 antagonism on spatial learning in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Blockade of mGluR glutamate receptors in the subthalamic nucleus ameliorates motor asymmetry in an animal model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Is impaired memory for spatial location in Parkinson's disease domain specific or dependent on 'strategic' processes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Memory for spatial location in 'de novo' parkinsonian patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

The selective mGlu(5) receptor agonist CHPG inhibits quinpirole-induced turning in 6-hydroxydopamine-lesioned rats and modulates the binding characteristics of dopamine D(2) receptors in the rat striatum: interactions with adenosine A(2a) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Involvement of glutamatergic and dopaminergic systems in the reactivity of mice to spatial and non-spatial change.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

The role of metabotropic glutamate receptor 5 in learning and memory processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Metabotropic glutamate receptor 1 blockade impairs acquisition and retention in a spatial Water maze task.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Glutamate release inhibiting properties of the novel mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP): complementary in vitro and in vivo evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Functional interaction between mGlu 5 and NMDA receptors in a rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Dopamine depletion, stimulation or blockade in the rat disrupts spatial navigation and locomotion dependent upon beacon or distal cues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Quantitative evaluation of 11C-ABP688 as PET ligand for the measurement of the metabotropic glutamate receptor subtype 5 using autoradiographic studies and a beta-scintillator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

Metabotropic glutamate 5 receptor blockade alleviates akinesia by normalizing activity of selective basal-ganglia structures in parkinsonian rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

7 January 2021

Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

7 January 2021

Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

7 January 2021

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

7 January 2021

NMDA and AMPA antagonist infusions into the ventral striatum impair different steps of spatial information processing in a nonassociative task in mice.

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

7 January 2021

Effects of the prototypical mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine on rotarod, locomotor activity and rotational responses in unilateral 6-OHDA-lesioned rats

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2008.129

7 January 2021

Identifiers

DOI

10.1038/NPP.2008.129

1 reference

22 December 2017

1 reference

22 December 2017