(Q46430806)

English

Venezuelan equine encephalitis replicon immunization overcomes intrinsic tolerance and elicits effective anti-tumor immunity to the 'self' tumor-associated antigen, neu in a rat mammary tumor model

scientific article published in December 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

Venezuelan equine encephalitis replicon immunization overcomes intrinsic tolerance and elicits effective anti-tumor immunity to the 'self' tumor-associated antigen, neu in a rat mammary tumor model (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

0 references

equine encephalitis

1 reference

based on heuristic

inferred from title

Venezuelan equine encephalitis

1 reference

based on heuristic

inferred from title

Edward L Nelson

1

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

4

object named as

Peter Pushko

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

author name string

Darue Prieto

2

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

Terri G Alexander

3

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

Loreen A Lofts

5

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

Jonathan O Rayner

6

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

Kurt I Kamrud

7

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

Bolyn Fralish

8

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

Jonathan F Smith

9

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

language of work or name

0 references

publication date

1 December 2003

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

Breast Cancer Research and Treatment

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

82

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

3

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

169-183

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

https://scigraph.springernature.com/pub.10.1023/b:brea.0000004373.09678.bb

0 references

Evaluation in nonhuman primates of vaccines against Ebola virus

1 reference

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21 January 2018

Vaccination with cytoplasmic ErbB-2 DNA protects mice from mammary tumor growth without anti-ErbB-2 antibody

1 reference

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21 January 2018

Complementary antitumor immunity induced by plasmid DNA encoding secreted and cytoplasmic human ErbB-2.

1 reference

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21 January 2018

Induction of tumor-reactive CTL by C-side chain variants of the CTL epitope HER-2/neu protooncogene (369-377) selected by molecular modeling of the peptide: HLA-A2 complex

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

21 January 2018

Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity

1 reference

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21 January 2018

HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy

1 reference

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21 January 2018

DNA vaccination against rat her-2/Neu p185 more effectively inhibits carcinogenesis than transplantable carcinomas in transgenic BALB/c mice.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

21 January 2018

Death mechanisms in cultured cells infected by Semliki Forest virus

1 reference

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21 January 2018

Cancer statistics, 2002

1 reference

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7 January 2021

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Expression of monoclonal-antibody-defined antigens in fractions isolated from human breast carcinomas and patients' serum

1 reference

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7 January 2021

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p53 gene mutation, tumor p53 protein overexpression, and serum p53 autoantibody generation in patients with breast cancer

1 reference

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7 January 2021

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High-titer HER-2/neu protein-specific antibody can be detected in patients with early-stage breast cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

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A phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Primary proliferative T cell response to wild-type p53 protein in patients with breast cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

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Cancer antigens: immune recognition of self and altered self

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

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Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Evolutionary relationships and systematics of the alphaviruses

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of dendritic cell targeting in Venezuelan equine encephalitis virus pathogenesis

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative immunization study using RNA and DNA constructs encoding a part of the Plasmodium falciparum antigen Pf332.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid, high level protein production using DNA-based Semliki Forest virus vectors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Semliki Forest virus-based DNA expression vector: transient protein production followed by cell death

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

A Sindbis virus mRNA polynucleotide vector achieves prolonged and high level heterologous gene expression in vivo

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Alphavirus vectors: development and potential therapeutic applications

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Semliki Forest virus-based vaccines: persistence, distribution and pathological analysis in two animal systems.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA vaccination against neu reduces breast cancer incidence and metastasis in mice

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer immunotherapy using Sindbis virus replicon particles encoding a VP22-antigen fusion.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancement of antitumor immune response in glioma models in mice by genetically modified dendritic cells pulsed with Semliki forest virus-mediated complementary DNA.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Sindbis virus replicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Immune protection against staphylococcal enterotoxin-induced toxic shock by vaccination with a Venezuelan equine encephalitis virus replicon

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Alphavirus replicon particles expressing the two major envelope proteins of equine arteritis virus induce high level protection against challenge with virulent virus in vaccinated horses

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Systemic, mucosal, and heterotypic immune induction in mice inoculated with Venezuelan equine encephalitis replicons expressing Norwalk virus-like particles

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Protection from Ebola virus mediated by cytotoxic T lymphocytes specific for the viral nucleoprotein

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Influenza virus (A/HK/156/97) hemagglutinin expressed by an alphavirus replicon system protects chickens against lethal infection with Hong Kong-origin H5N1 viruses

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Recombinant RNA replicons derived from attenuated Venezuelan equine encephalitis virus protect guinea pigs and mice from Ebola hemorrhagic fever virus

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Marburg virus vaccines based upon alphavirus replicons protect guinea pigs and nonhuman primates.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Vaccination with Her-2/neu DNA or protein subunits protects against growth of a Her-2/neu-expressing murine tumor

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

HER2 peptide-specific CD8(+) T cells are proportionally detectable long after multiple DNA vaccinations

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined allogeneic tumor cell vaccination and systemic interleukin 12 prevents mammary carcinogenesis in HER-2/neu transgenic mice

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of spontaneous neu-expressing mammary tumor development in mice transgenic for rat proto-neu by DNA vaccination.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Insertion of the DNA for the 163-171 peptide of IL1beta enables a DNA vaccine encoding p185(neu) to inhibit mammary carcinogenesis in Her-2/neu transgenic BALB/c mice

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

The neu oncogene encodes an epidermal growth factor receptor-related protein

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

The ErbB signaling network: receptor heterodimerization in development and cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Generation of T-cell immunity to the HER-2/neu protein after active immunization with HER-2/neu peptide-based vaccines

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

MHC-binding peptides as immunotherapeutics for cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

The HER2/neu-derived peptide p654-662 is a tumor-associated antigen in human pancreatic cancer recognized by cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Shared T cell epitopes in epithelial tumors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

HER-2/neu-derived peptide 884-899 is expressed by human breast, colorectal and pancreatic adenocarcinomas and is recognized by in-vitro-induced specific CD4(+) T cell clones

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Peptide HER2(776-788) represents a naturally processed broad MHC class II-restricted T cell epitope

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Development of a cancer vaccine: peptides, proteins, and DNA

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Protection against mammary tumor growth by vaccination with full-length, modified human ErbB-2 DNA.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Generation of cellular immune responses to antigenic tumor peptides

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

HER-2/neu protein: a target for antigen-specific immunotherapy of human cancer.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA vaccination with full-length or truncated neu induces protective immunity against the development of spontaneous mammary tumors in HER-2/neu transgenic mice

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic immunization against neu/erbB2 transgenic breast cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Monoclonal and polyclonal humoral immune response to EC HER-2/NEU peptides with low similarity to the host's proteome

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

ErbB2 is essential in the prevention of dilated cardiomyopathy.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

HLA class I expression on human cancer cells. Implications for effective immunotherapy

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

A new generation of animal cell expression vectors based on the Semliki Forest virus replicon

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Virus infection induces neuronal apoptosis: A comparison with trophic factor withdrawal

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptotic cell death is an important cause of neuronal injury in experimental Venezuelan equine encephalitis virus infection of mice

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of apoptosis by Sindbis virus occurs at cell entry and does not require virus replication.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Sindbis virus entry into cells triggers apoptosis by activating sphingomyelinase, leading to the release of ceramide

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of Sindbis virus-induced pathology in mosquito and vertebrate cell cultures

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Alphavirus vectors for gene therapy applications

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of human lung carcinoma cell growth by apoptosis induction using Semliki Forest virus recombinant particles

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of apoptosis in BCL-2-expressing rat prostate cancer cells using the Semliki Forest virus vector

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Sindbis virus-induced neuronal death is both necrotic and apoptotic and is ameliorated by N-methyl-D-aspartate receptor antagonists

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Sindbis virus induces apoptosis through a caspase-dependent, CrmA-sensitive pathway.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel packages of viral and self-antigens are generated during apoptosis

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Infection of glioma cells with Sindbis virus induces selective activation and tyrosine phosphorylation of protein kinase C delta. Implications for Sindbis virus-induced apoptosis

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000004373.09678.BB

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1023/B:BREA.0000004373.09678.BB

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/14703064

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