(Q46439472)

22 December 2017

title

Single-dose pharmacokinetic interaction between artesunate and amodiaquine: assembling the clues for the purported interaction (English)

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22 December 2017

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Nuggehally R Srinivas

series ordinal

1

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22 December 2017

publication date

8 August 2008

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22 December 2017

European Journal of Clinical Pharmacology

published in

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22 December 2017

volume

64

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22 December 2017

issue

12

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22 December 2017

page(s)

1231-1233

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22 December 2017

https://scigraph.springernature.com/pub.10.1007/s00228-008-0539-x

exact match

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cites work

Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate

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12 December 2020

Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum in Afghanistan

1 reference

12 December 2020

Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data

1 reference

12 December 2020

Effects of prior administration of amodiaquine on the disposition of halofantrine in healthy volunteers.

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12 December 2020

Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa

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12 December 2020

Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects

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12 December 2020

Assessment of the effect of mefloquine on artesunate pharmacokinetics in healthy male volunteers

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12 December 2020

Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers

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12 December 2020

Lack of impact of artesunate on the disposition kinetics of sulfadoxine/pyrimethamine when the two drugs are concomitantly administered

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12 December 2020

Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers

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12 December 2020

Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo

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12 December 2020

Pharmacodynamic interactions of amodiaquine and its major metabolite desethylamodiaquine with artemisinin, quinine and atovaquone in Plasmodium falciparum in vitro

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12 December 2020

Toxicokinetics and hydrolysis of artelinate and artesunate in malaria-infected rats

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12 December 2020

Clinical pharmacology of artemisinin-based combination therapies

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12 December 2020

Efficacy and safety of artesunate plus amodiaquine in routine use for the treatment of uncomplicated malaria in Casamance, southern Sénégal

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12 December 2020

Absence of an interaction between artesunate and atovaquone--proguanil

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12 December 2020

10.1007/S00228-008-0539-X

Identifiers

DOI

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22 December 2017

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22 December 2017