(Q46440176)

22 December 2017

title

Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice (English)

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22 December 2017

15

Ichinosuke Hyodo

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22 December 2017

author name string

Kosuke Okada

1

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22 December 2017

Junichi Shoda

2

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22 December 2017

Keiko Taguchi

3

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22 December 2017

Jonathan M Maher

4

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22 December 2017

Kaoru Ishizaki

5

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22 December 2017

Yoshimi Inoue

6

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22 December 2017

Makio Ohtsuki

7

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22 December 2017

Nobuharu Goto

8

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22 December 2017

Koichi Takeda

9

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22 December 2017

Hirotoshi Utsunomiya

10

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22 December 2017

Koji Oda

11

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22 December 2017

Eiji Warabi

12

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22 December 2017

Tetsuro Ishii

13

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22 December 2017

Keiko Osaka

14

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22 December 2017

Masayuki Yamamoto

16

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22 December 2017

publication date

7 August 2008

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22 December 2017

American Journal of Physiology - Gastrointestinal and Liver Physiology

published in

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22 December 2017

volume

295

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22 December 2017

issue

4

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22 December 2017

page(s)

G735-47

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22 December 2017

Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2

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1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

MRP3, an organic anion transporter able to transport anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Regulation of the multidrug resistance protein 2 in the rat liver by lipopolysaccharide and dexamethasone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Ursodeoxycholic acid protects hepatocytes against oxidative injury via induction of antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Functional modulation of the glucocorticoid receptor and suppression of NF-kappaB-dependent transcription by ursodeoxycholic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Combined analysis of randomized controlled trials of ursodeoxycholic acid in primary biliary cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Ursodeoxycholic acid for primary biliary cirrhosis: lessons from the past--issues for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Effect of ursodeoxycholic acid on methionine adenosyltransferase activity and hepatic glutathione metabolism in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Ursodeoxycholic acid protects against secondary biliary cirrhosis in rats by preventing mitochondrial oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Genipin enhances Mrp2 (Abcc2)-mediated bile formation and organic anion transport in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Near completely humanized liver in mice shows human-type metabolic responses to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.90321.2008

21 January 2018

Identifiers

DOI

10.1152/AJPGI.90321.2008

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22 December 2017

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22 December 2017