(Q46443030)

22 December 2017

title

Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants (English)

1 reference

22 December 2017

author name string

Lazara Karelia Montané Jaime

1

1 reference

22 December 2017

Anthony Lalla

2

1 reference

22 December 2017

Werner Steimer

3

1 reference

22 December 2017

Andrea Gaedigk

4

1 reference

22 December 2017

publication date

1 February 2013

1 reference

22 December 2017

published in

Pharmacogenomics

1 reference

22 December 2017

volume

14

1 reference

22 December 2017

issue

3

1 reference

22 December 2017

page(s)

261-276

1 reference

22 December 2017

Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity

cites work

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

The impact of the CYP2D6-polymorphism on dose recommendations for current antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Interethnic differences in genetic polymorphisms of CYP2D6 in the U.S. population: clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Genotype and allele frequency of CYP2D6 in Tamilian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

CYP2D6 genetic polymorphism in South Indian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Genetic polymorphism of CYP2D6 in a keralite (South India) population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

The theory and practice of consultation-liaison (CL) psychiatry in Trinidad and Tobago with reference to suicidal behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Depression and the nature of Trinidadian family practice: a cross-sectional study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Cannabis and suicidal behaviour among adolescents: a pilot study from Trinidad.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

American Society of Clinical Oncology clinical practice guideline: update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Discovery of a novel nonfunctional cytochrome P450 2D6 allele, CYP2D642, in African American subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

The CYP2D6 gene locus in South African Coloureds: unique allele distributions, novel alleles and gene arrangements.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Allele-specific change of concentration and functional gene dose for the prediction of steady-state serum concentrations of amitriptyline and nortriptyline in CYP2C19 and CYP2D6 extensive and intermediate metabolizers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

CYP2D6 update: revised nomenclature for CYP2D7/2D6 hybrid genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

CYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Evaluation of probe drugs and pharmacokinetic metrics for CYP2D6 phenotyping

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

Dextromethorphan to dextrorphan urinary metabolic ratio does not reflect dextromethorphan oral clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

CYP2D6 genotype and debrisoquine hydroxylation phenotype in Cubans and Nicaraguans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.207

21 January 2018

Identifiers

DOI

10.2217/PGS.12.207

1 reference

22 December 2017

1 reference

22 December 2017