(Q46446511)

22 December 2017

title

The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis (English)

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22 December 2017

6

Sabine Werner

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22 December 2017

Weihua Xu

1

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22 December 2017

Claus Hellerbrand

2

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22 December 2017

Ulrike A Köhler

3

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22 December 2017

Philippe Bugnon

4

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22 December 2017

Yuet-Wai Kan

5

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22 December 2017

Tobias A Beyer

7

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22 December 2017

publication date

4 August 2008

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22 December 2017

published in

Laboratory Investigation

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22 December 2017

volume

88

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22 December 2017

issue

10

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22 December 2017

page(s)

1068-1078

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22 December 2017

https://scigraph.springernature.com/pub.10.1038/labinvest.2008.75

exact match

0 references

cites work

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Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

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The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress

21 January 2018

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Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance

21 January 2018

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An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

21 January 2018

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High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

21 January 2018

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Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1.

21 January 2018

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Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stress

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Involvement of phosphatidylinositol 3-kinase and extracellular-regulated kinase in hepatic stellate cell antioxidant response and myofibroblastic transdifferentiation

21 January 2018

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Nuclear factor-E2-related factor 2 expression in liver is critical for induction of NAD(P)H:quinone oxidoreductase 1 during cholestasis.

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Nrf2 is essential for protection against acute pulmonary injury in mice

21 January 2018

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Matrix metalloproteinases (MMPs) and their physiological inhibitors (TIMPs) are differentially expressed during excisional skin wound repair

21 January 2018

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PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis

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Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair

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The dermal microenvironment induces the expression of the alternative activation marker CD301/mMGL in mononuclear phagocytes, independent of IL-4/IL-13 signaling.

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Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis.

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Curcumin protects the rat liver from CCl4-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation

21 January 2018

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Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray

21 January 2018

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Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice.

21 January 2018

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The effects of allyl sulfides on the induction of phase II detoxification enzymes and liver injury by carbon tetrachloride

21 January 2018

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Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.

21 January 2018

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Interleukin-10 expression and function in experimental murine liver inflammation and fibrosis

21 January 2018

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7 January 2021

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation.

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7 January 2021

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7 January 2021

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7 January 2021

Alcohol, oxidative stress and free radical damage

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https://api.crossref.org/works/10.1038%2FLABINVEST.2008.75

7 January 2021

10.1038/LABINVEST.2008.75

Identifiers

DOI

1 reference

22 December 2017

PubMed ID

18679376

1 reference

22 December 2017