(Q46448081)

22 December 2017

title

Cytochrome P450 1B1 is required for 7,12-dimethylbenz(a)-anthracene (DMBA) induced spleen cell immunotoxicity (English)

1 reference

22 December 2017

author name string

Jun Gao

1

1 reference

22 December 2017

Fredine T Lauer

2

1 reference

22 December 2017

Sandy Dunaway

3

1 reference

22 December 2017

Scott W Burchiel

4

1 reference

22 December 2017

publication date

20 April 2005

1 reference

22 December 2017

published in

Toxicological Sciences

1 reference

22 December 2017

volume

86

1 reference

22 December 2017

issue

1

1 reference

22 December 2017

page(s)

68-74

1 reference

22 December 2017

Covalent binding of 7,12-dimethylbenz[a]anthracene to lymphoid and nonlymphoid tissues following oral administration to B6C3F1 mice

cites work

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Inhibition of lymphocyte activation in splenic and gut-associated lymphoid tissues following oral exposure of mice to 7,12-dimethylbenz[a]anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Hardwood smoke alters murine splenic T cell responses to mitogens following a 6-month whole body inhalation exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Systemic immunotoxicity in AJ mice following 6-month whole body inhalation exposure to diesel exhaust.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

CYP1B1 determines susceptibility to low doses of 7,12-dimethylbenz[a]anthracene-induced ovarian cancers in mice: correlation of CYP1B1-mediated DNA adducts with carcinogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Suppression of local gut-associated and splenic mitogen responsiveness of lymphoid cells following oral exposure of B6C3F1 mice to 7,12-dimethylbenz6a9anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

The aryl hydrocarbon receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Immunization of dissociated spleen cell cultures from normal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Clinical importance of the cytochromes P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

7-12 Dimethylbenz[a]anthracene-induced bone marrow hypocellularity is dependent on signaling through both the TNFR and PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

7,12-Dimethylbenz[a]anthracene-Induced Bone Marrow Toxicity Is p53-Dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Immunosuppression following exposure to 7,12-dimethylbenz[a]anthracene (DMBA) in Ah-responsive and Ah-nonresponsive mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI176

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFI176

1 reference

22 December 2017

1 reference

22 December 2017