(Q46462885)

English

Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice

scientific article published in March 2005

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice (English)

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

1 reference

based on heuristic

inferred from title

2

object named as

Andrzej Bartke

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

author name string

Zelton Dave Sharp

1

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

language of work or name

0 references

publication date

1 March 2005

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

The Journals of Gerontology

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

60

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

3

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

293-300

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

Sequences of pituitary and placental lactogenic and growth hormones: evolution from a primordial peptide by gene reduplication

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Structure and evolution of the growth hormone gene family

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor beta-chain

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Control of growth by the somatropic axis: growth hormone and the insulin-like growth factors have related and independent roles

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Distinct and overlapping functions of insulin and IGF-I receptors

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

The somatomedin hypothesis: 2001.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Signaling mechanisms of cytokine receptors and their perturbances in disease.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Blood-brain barrier for human growth hormone and insulin-like growth factor-I.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Effects of growth hormone overexpression and growth hormone resistance on neuroendocrine and reproductive functions in transgenic and knock-out mice

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Growth hormone replacement therapy for adults: into the new millennium.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Roles of prolactin and related members of the prolactin/growth hormone/placental lactogen family in angiogenesis

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

The therapeutic problem of proliferative diabetic retinopathy: targeting somatostatin receptors.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Octreotide reduces vitreous hemorrhage and loss of visual acuity risk in patients with high-risk proliferative diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Signaling pathways activated by the growth hormone receptor

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Prolonged longevity of hypopituitary dwarf mice

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Normal growth and development in the absence of hepatic insulin-like growth factor I

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Gigantism in mice lacking suppressor of cytokine signalling-2

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Regulation of translation initiation by FRAP/mTOR

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Oncogenic kinase signalling

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

The TOR kinases link nutrient sensing to cell growth

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

TOR, a central controller of cell growth

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

The anabolic actions of growth hormone and thyroxine on protein metabolism in Snell dwarf and normal mice

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

The GH-transgenic mouse as an experimental model for growth research: clinical and pathological studies.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Histopathology associated with elevated levels of growth hormone and insulin-like growth factor I in transgenic mice

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Hormonal regulation of human muscle protein metabolism

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Simultaneous activation of p90rsk and p70s6k S6 kinases by growth hormone in 3T3-F442A preadipocytes

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Requirement for phosphoinositide 3-OH kinase in growth hormone signalling to the mitogen-activated protein kinase and p70s6k pathways

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F442A preadipocytes

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Tuberous sclerosis complex: from Drosophila to human disease.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Assessment of growth parameters and life span of GHR/BP gene-disrupted mice.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Dwarf mice and the ageing process.

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Extended longevity in mice lacking the insulin receptor in adipose tissue

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Extending the lifespan of long-lived mice

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Genetics: influence of TOR kinase on lifespan in C. elegans

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

1 reference

https://api.crossref.org/works/10.1093%2FGERONA%2F60.3.293

21 January 2018

Identifiers

10.1093/GERONA/60.3.293

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/15860463

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q46462885&oldid=2112869344"