(Q46491347)

22 December 2017

title

The product chain length determination mechanism of type II geranylgeranyl diphosphate synthase requires subunit interaction (English)

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22 December 2017

author

Hisashi Hemmi

6

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22 December 2017

author name string

Motoyoshi Noike

1

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22 December 2017

Takashi Katagiri

2

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22 December 2017

Toru Nakayama

3

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22 December 2017

Tanetoshi Koyama

4

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22 December 2017

Tokuzo Nishino

5

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22 December 2017

language of work or name

English

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publication date

4 July 2008

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22 December 2017

published in

FEBS Journal

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22 December 2017

volume

275

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22 December 2017

issue

15

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22 December 2017

page(s)

3921-3933

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22 December 2017

Molecular analysis of prenyl chain elongating enzymes

cites work

1 reference

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Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution

21 January 2018

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Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination

21 January 2018

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Crystallization and preliminary X-ray diffraction study of the farnesyl diphosphate synthase from Trypanosoma brucei

21 January 2018

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Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis

21 January 2018

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Homodimeric hexaprenyl pyrophosphate synthase from the thermoacidophilic crenarchaeon Sulfolobus solfataricus displays asymmetric subunit structures

21 January 2018

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The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding

21 January 2018

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The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs

21 January 2018

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Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: implications for drug design

21 January 2018

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Human geranylgeranyl diphosphate synthase. cDNA cloning and expression

21 January 2018

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Chain-length determination mechanism of isoprenyl diphosphate synthases and implications for molecular evolution.

21 January 2018

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An alternative mechanism of product chain-length determination in type III geranylgeranyl diphosphate synthase

21 January 2018

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Conversion of product specificity of archaebacterial geranylgeranyl-diphosphate synthase. Identification of essential amino acid residues for chain length determination of prenyltransferase reaction.

21 January 2018

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Regulation of product chain length by isoprenyl diphosphate synthases

21 January 2018

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Conversion from farnesyl diphosphate synthase to geranylgeranyl diphosphate synthase by random chemical mutagenesis.

21 January 2018

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Structure and reaction geometry of geranylgeranyl diphosphate synthase from Sinapis alba

21 January 2018

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Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases

21 January 2018

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Directed evolution of Escherichia coli farnesyl diphosphate synthase (IspA) reveals novel structural determinants of chain length specificity

21 January 2018

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Interaction with the small subunit of geranyl diphosphate synthase modifies the chain length specificity of geranylgeranyl diphosphate synthase to produce geranyl diphosphate

21 January 2018

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Molecular Cloning and Nucleotide Sequences of the Genes for Two Essential Proteins Constituting a Novel Enzyme System for Heptaprenyl Diphosphate Synthesis

21 January 2018

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Two cistrons of the gerC operon of Bacillus subtilis encode the two subunits of heptaprenyl diphosphate synthase

21 January 2018

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Two subunits of heptaprenyl diphosphate synthase of Bacillus subtilis form a catalytically active complex.

21 January 2018

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Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans

21 January 2018

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Fission yeast decaprenyl diphosphate synthase consists of Dps1 and the newly characterized Dlp1 protein in a novel heterotetrameric structure

21 January 2018

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A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products

21 January 2018

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21 January 2018

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Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

1 reference

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Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase fromSaccharomyces cerevisiaeand the Mechanism of Product Chain Length Determination

21 January 2018

1 reference

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10.1111/J.1742-4658.2008.06538.X

21 January 2018

Identifiers

DOI

1 reference

22 December 2017

1 reference

22 December 2017