(Q27642782)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672944%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis (English)

1 reference

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22 December 2019

6

1 reference

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22 December 2019

author name string

David J Hosfield

1

1 reference

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22 December 2019

Yanming Zhang

2

1 reference

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22 December 2019

Douglas R Dougan

3

1 reference

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22 December 2019

Alexei Broun

4

1 reference

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22 December 2019

Leslie W Tari

5

1 reference

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22 December 2019

John Finn

7

1 reference

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22 December 2019

language of work or name

English

0 references

publication date

12 December 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672944%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

22 December 2019

published in

1 reference

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22 December 2019

volume

279

1 reference

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22 December 2019

issue

10

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22 December 2019

page(s)

8526-8529

1 reference

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The branch point enzyme of the mevalonate pathway for protein prenylation is overexpressed in the ob/ob mouse and induced by adipogenesis

22 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Isoprenoid Pyrophosphate Analogues Regulate Expression of Ras-Related Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Purification and characterization of recombinant human farnesyl diphosphate synthase expressed in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Farnesyl pyrophosphate synthase is an essential enzyme in Trypanosoma brucei. In vitro RNA interference and in vivo inhibition studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Promising therapeutic targets for antileishmanial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

New Insights Into the Molecular Mechanisms of Action of Bisphosphonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Bisphosphonate treatment of osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Bisphosphonate therapy in Paget disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Antitumor effects of bisphosphonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Regulation of product chain length by isoprenyl diphosphate synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Thermostable farnesyl diphosphate synthase of Bacillus stearothermophilus: molecular cloning, sequence determination, overproduction, and purification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

The pleiotropic effects of HMG-CoA reductase inhibitors: their role in osteoporosis and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

A fully integrated protein crystallization platform for small-molecule drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C300511200

21 January 2018

Identifiers

DOI

10.1074/JBC.C300511200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14672944%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference