(Q28240022)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16698791%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding (English)

1 reference

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21 January 2020

0 references

2

1 reference

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21 January 2020

Robert Graham G Russell

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16698791%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

5

Udo Oppermann

1 reference

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21 January 2020

author name string

Kathryn L Kavanagh

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16698791%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Gabor Bunkoczi

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16698791%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

11 May 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16698791%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

21 January 2020

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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21 January 2020

volume

281

1 reference

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21 January 2020

issue

31

1 reference

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21 January 2020

page(s)

22004-22012

1 reference

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Regulation of fatty acid synthesis by farnesyl pyrophosphate

21 January 2020

cites work

1 reference

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The nuclear receptors FXR and LXRalpha: potential targets for the development of drugs affecting lipid metabolism and neoplastic diseases

21 January 2018

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Functional aspects of polyisoprenoid protein substituents: roles in protein-protein interaction and trafficking

21 January 2018

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Recent advances in the study of prenylated proteins

21 January 2018

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Phosphonocarboxylate inhibitors of Rab geranylgeranyl transferase disrupt the prenylation and membrane localization of Rab proteins in osteoclasts in vitro and in vivo

21 January 2018

1 reference

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Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.

21 January 2018

1 reference

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The role of prenylated small GTP-binding proteins in the regulation of osteoclast function

21 January 2018

1 reference

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Identification of a novel phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages.

21 January 2018

1 reference

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Role of prenylation in the interaction of Rho-family small GTPases with GTPase activating proteins.

21 January 2018

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Bisphosphonates: from the laboratory to the clinic and back again

21 January 2018

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Lipid posttranslational modifications. Farnesyl transferase inhibitors

21 January 2018

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Inhibition of isoprene biosynthesis pathway enzymes by phosphonates, bisphosphonates, and diphosphates

21 January 2018

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Antiparasitic activity of risedronate in a murine model of acute Chagas' disease.

21 January 2018

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The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs

21 January 2018

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Preparation of selenomethionyl proteins for phase determination

21 January 2018

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A solution for the best rotation to relate two sets of vectors

21 January 2018

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Coot: model-building tools for molecular graphics

21 January 2018

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Likelihood-enhanced fast translation functions

21 January 2018

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Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

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Substrate binding of avian liver prenyltransferase

21 January 2018

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Human geranylgeranyl diphosphate synthase. cDNA cloning and expression

21 January 2018

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Human liver prenyltransferase and its characterization

21 January 2018

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Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis

21 January 2018

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Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: implications for drug design

21 January 2018

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Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.

21 January 2018

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Regulation of product chain length by isoprenyl diphosphate synthases

21 January 2018

1 reference

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Mechanism of the prenyl transfer reaction. Studies with (E)- and (Z)-3-trifluoromethyl-2-buten-1-yl pyrophosphate

21 January 2018

1 reference

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Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602603200

Crystal structure of recombinant farnesyl diphosphate synthase at 2.6-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602603200

Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase fromSaccharomyces cerevisiaeand the Mechanism of Product Chain Length Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602603200

21 January 2018

Identifiers

DOI

10.1074/JBC.M602603200

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16698791%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017