(Q46540924)

23 December 2017

title

The emerging CK2 interactome: insights into the regulation and functions of CK2. (English)

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23 December 2017

author name string

Laszlo Gyenis

series ordinal

1

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23 December 2017

David W Litchfield

series ordinal

2

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23 December 2017

language of work or name

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14 June 2008

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23 December 2017

Molecular and Cellular Biochemistry

published in

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23 December 2017

volume

316

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23 December 2017

issue

1-2

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23 December 2017

page(s)

5-14

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23 December 2017

https://scigraph.springernature.com/pub.10.1007/s11010-008-9830-5

exact match

0 references

cites work

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Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2.

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Toward a comprehensive atlas of the physical interactome of Saccharomyces cerevisiae

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The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta

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Functional organization of the yeast proteome by systematic analysis of protein complexes

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Phosphorylation regulates the stability of the regulatory CK2beta subunit

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The regulation of protein function by multisite phosphorylation--a 25 year update

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An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets

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Yeast holoenzyme of protein kinase CK2 requires both beta and beta' regulatory subunits for its activity.

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Interactions between protein kinase CK2 and Pin1. Evidence for phosphorylation-dependent interactions

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Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization

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Globozoospermia in mice lacking the casein kinase II alpha' catalytic subunit

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Protein kinase CK2: a challenge to canons

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The BioGRID Interaction Database: 2008 update

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A comprehensive two-hybrid analysis to explore the yeast protein interactome

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Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.

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A probabilistic functional network of yeast genes

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Evolution of protein kinase signaling from yeast to man

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A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1

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On the physiological role of casein kinase II in Saccharomyces cerevisiae.

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Modulation of human checkpoint kinase Chk1 by the regulatory beta-subunit of protein kinase CK2

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Casein kinase II in signal transduction and cell cycle regulation

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Order or chaos? An evaluation of the regulation of protein kinase CK2.

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Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

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Asymmetric expression of protein kinase CK2 subunits in human kidney tumors

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BioGRID: a general repository for interaction datasets

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Phosphorylation of the regulatory beta-subunit of protein kinase CK2 by checkpoint kinase Chk1: identification of the in vitro CK2beta phosphorylation site

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12 December 2020

CK2 interacting proteins: emerging paradigms for CK2 regulation?

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12 December 2020

Towards a proteome-scale map of the human protein–protein interaction network

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Kinomics: methods for deciphering the kinome

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Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation

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Live-cell fluorescence imaging reveals the dynamics of protein kinase CK2 individual subunits.

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12 December 2020

Development of a stabilized form of the regulatory CK2beta subunit that inhibits cell proliferation

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Expression and localization of epitope-tagged protein kinase CK2

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Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

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Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung

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Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer

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The shape of things to come: an emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton

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Elevated protein kinase CK2 activity in chromatin of head and neck tumors: association with malignant transformation.

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Genes targeted by protein kinase CK2: a genome-wide expression array analysis in yeast

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CK2: a protein kinase in need of control.

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Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

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Joining the cell survival squad: an emerging role for protein kinase CK2.

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HIV-1 Rev transactivator: a beta-subunit directed substrate and effector of protein kinase CK2.

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12 December 2020

Proteome survey reveals modularity of the yeast cell machinery

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Large-scale mapping of human protein-protein interactions by mass spectrometry

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PTEN is destabilized by phosphorylation on Thr366.

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12 December 2020

Phosphorylation of calmodulin fragments by protein kinase CK2. Mechanistic aspects and structural consequences.

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12 December 2020

Protein kinase CK2 is a key activator of histone deacetylase in hypoxia-associated tumors

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12 December 2020

Nuclear casein kinase 2 (CK-2) activity in human normal, benign hyperplastic, and cancerous prostate

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12 December 2020

Get ready to GO! A biologist's guide to the Gene Ontology

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12 December 2020

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

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12 December 2020

Phosphorylation of casein kinase II by p34cdc2. Identification of phosphorylation sites using phosphorylation site mutants in vitro

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12 December 2020

p53 deficiency and misexpression of protein kinase CK2alpha collaborate in the development of thymic lymphomas in mice

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12 December 2020

Protein kinase CK2 structure-function relationship: effects of the beta subunit on reconstitution and activity.

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12 December 2020

Functional specialization of CK2 isoforms and characterization of isoform-specific binding partners

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12 December 2020

Phosphorylation of casein kinase II by p34cdc2 in vitro and at mitosis

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12 December 2020

Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis

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12 December 2020

Phosphorylation of casein kinase II.

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12 December 2020

Role of protein kinase CK2 in the regulation of tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis in prostate cancer cells

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12 December 2020

The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein

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12 December 2020

p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex

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12 December 2020

Regulation of histone deacetylase 2 by protein kinase CK2.

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12 December 2020

The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein

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12 December 2020

Protein kinase casein kinase 2 mediates inhibitor-kappaB kinase and aberrant nuclear factor-kappaB activation by serum factor(s) in head and neck squamous carcinoma cells

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12 December 2020

One-thousand-and-one substrates of protein kinase CK2?

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12 December 2020

Phosphorylation of the beta subunit of casein kinase II in human A431 cells. Identification of the autophosphorylation site and a site phosphorylated by p34cdc2.

1 reference

12 December 2020

The Pleckstrin homology domain of CK2 interacting protein-1 is required for interactions and recruitment of protein kinase CK2 to the plasma membrane

1 reference

12 December 2020

Protein kinase CK2 in mammary gland tumorigenesis

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12 December 2020

Mass Spectrometry Analysis of a Protein Kinase CK2β Subunit Interactome Isolated from Mouse Brain by Affinity Chromatography

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12 December 2020

Subcellular localization of protein kinase CK2. A key to its function?

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12 December 2020

A global view of CK2 function and regulation.

1 reference

12 December 2020

Identification and characterization of CKIP-1, a novel pleckstrin homology domain-containing protein that interacts with protein kinase CK2

1 reference

12 December 2020

GOChase: correcting errors from Gene Ontology-based annotations for gene products

1 reference

12 December 2020

10.1007/S11010-008-9830-5

Identifiers

DOI

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23 December 2017

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23 December 2017