(Q46560325)

23 December 2017

title

Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels (English)

1 reference

23 December 2017

main subject

Conus striatus

Conus striatus

1 reference

based on heuristic

inferred from title

author

Christina I. Schroeder

1

1 reference

23 December 2017

Richard J. Lewis

9

1 reference

23 December 2017

David J. Adams

David J Adams

7

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Jenny Ekberg

Jenny Ekberg

2

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Paul F Alewood

Paul F Alewood

8

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author name string

Katherine J Nielsen

3

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23 December 2017

Denise Adams

4

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23 December 2017

Marion L Loughnan

5

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23 December 2017

Linda Thomas

6

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23 December 2017

language of work or name

English

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publication date

3 June 2008

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23 December 2017

Journal of Biological Chemistry

number of pages

8

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based on heuristic

inferred from page(s)

published in

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23 December 2017

volume

283

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23 December 2017

issue

31

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23 December 2017

page(s)

21621-21628

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23 December 2017

From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

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1 reference

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Voltage-gated sodium channels and pain pathways

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Low dose of tetrodotoxin reduces neuropathic pain behaviors in an animal model.

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Potent analgesic effects of GDNF in neuropathic pain states.

21 January 2018

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Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain

21 January 2018

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SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes

21 January 2018

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An SCN9A channelopathy causes congenital inability to experience pain

21 January 2018

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Molecular mechanisms of neurotoxin action on voltage-gated sodium channels.

21 January 2018

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kappa-Conotoxin PVIIA is a peptide inhibiting the shaker K+ channel

21 January 2018

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Solution structure of mu-conotoxin PIIIA, a preferential inhibitor of persistent tetrodotoxin-sensitive sodium channels

21 January 2018

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Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels.

21 January 2018

1 reference

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Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons

21 January 2018

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Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels.

21 January 2018

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A novel conotoxin from Conus striatus, mu-SIIIA, selectively blocking rat tetrodotoxin-resistant sodium channels

21 January 2018

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Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

21 January 2018

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Structure-activity relationships of mu-conotoxin GIIIA: structure determination of active and inactive sodium channel blocker peptides by NMR and simulated annealing calculations

21 January 2018

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Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels

21 January 2018

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Structure-activity relationships of omega-conotoxins MVIIA, MVIIC and 14 loop splice hybrids at N and P/Q-type calcium channels

21 January 2018

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Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.

21 January 2018

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Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

21 January 2018

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1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects

21 January 2018

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Torsion angle dynamics for NMR structure calculation with the new program DYANA

21 January 2018

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New applications of simulated annealing in X-ray crystallography and solution NMR.

21 January 2018

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Twists, knots, and rings in proteins. Structural definition of the cyclotide framework

21 January 2018

1 reference

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Modification of Arg-13 of mu-conotoxin GIIIA with piperidinyl-Arg analogs and their relation to the inhibition of sodium channels

21 January 2018

1 reference

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Action of derivatives of mu-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M802852200

1 reference

23 December 2017

PubMed ID

18522941

1 reference

23 December 2017