(Q48784731)

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Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

scientific article published on 27 August 2007

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scholarly article

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4 January 2020

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels (English)

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4 January 2020

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Jeffrey R. McArthur

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Raymond S Norton

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4 January 2020

Baldomero Olivera

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Baldomero M Olivera

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Layla Azam

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Philip Catlin

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Heinrich Terlau

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Heinrich Terlau

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Doju Yoshikami

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Min-Min Zhang

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Brad R Green

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Brian Fiedler

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Ashley Chadwick

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Robert J French

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Josef Gulyas

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Jean E Rivier

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Grzegorz Bulaj

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publication date

27 August 2007

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4 January 2020

Journal of Biological Chemistry

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30699-30706

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4 January 2020

Conus venoms: a rich source of novel ion channel-targeted peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Conotoxins down under

1 reference

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21 January 2018

Conotoxins as research tools and drug leads

1 reference

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21 January 2018

Drugs from the sea: conopeptides as potential therapeutics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Sodium channel toxins--receptor targeting and therapeutic potential

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

A new family of conotoxins that blocks voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

mu-conotoxin GIIIA, a peptide ligand for muscle sodium channels: chemical synthesis, radiolabeling, and receptor characterization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Effects of delta-conotoxins PVIA and SVIE on sodium channels in the amphibian sympathetic nervous system.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

A novel conotoxin from Conus striatus, mu-SIIIA, selectively blocking rat tetrodotoxin-resistant sodium channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Voltage-gated sodium channels and pain pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

NaN/Nav1.9: a sodium channel with unique properties

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Electrostatic and steric contributions to block of the skeletal muscle sodium channel by mu-conotoxin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Block of sodium channels in planar lipid bilayers by guanidium toxins and calcium. Are the mechanisms of voltage dependence the same?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Interactions between a pore-blocking peptide and the voltage sensor of the sodium channel: an electrostatic approach to channel geometry.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

A comparison of the anti-nociceptive effects of voltage-activated Na+ channel blockers in the formalin test

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Antinociceptive effects of tetrodotoxin (TTX) in rodents.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Comparison of the effects of four Na+ channel analgesics on TTX-resistant Na+ currents in rat sensory neurons and recombinant Nav1.2 channels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

An SCN9A channelopathy causes congenital inability to experience pain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

mu-conotoxin GIIIA interactions with the voltage-gated Na(+) channel predict a clockwise arrangement of the domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

A mu-conotoxin-insensitive Na+ channel mutant: possible localization of a binding site at the outer vestibule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Pore-blocking toxins as probes of voltage-dependent channels.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Clockwise domain arrangement of the sodium channel revealed by (mu)-conotoxin (GIIIA) docking orientation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Conus peptides: biodiversity-based discovery and exogenomics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704616200

21 January 2018

Subtype-selective sodium channel blockers promise a new era of pain research

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M704616200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724025%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

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4 January 2020

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