(Q46617670)

23 December 2017

http://europepmc.org/abstract/MED/18448655

title

Thromboxane receptor activation mediates isoprostane-induced increases in amyloid pathology in Tg2576 mice (English)

1 reference

23 December 2017

http://europepmc.org/abstract/MED/18448655

0 references

Diana W Shineman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

Bin Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

Susan N Leight

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

Domenico Pratico

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

Virginia M-Y Lee

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

language of work or name

English

0 references

publication date

1 April 2008

1 reference

23 December 2017

http://europepmc.org/abstract/MED/18448655

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

page(s)

4785-4794

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

Characterization of 8-epiprostaglandin F2alpha as a marker of amyloid beta-peptide-induced oxidative damage.

16 May 2020

cites work

1 reference

12 December 2020

Translating cell biology into therapeutic advances in Alzheimer's disease

1 reference

12 December 2020

Intracellular APP processing and A beta production in Alzheimer disease

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12 December 2020

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

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12 December 2020

Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network

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12 December 2020

Thromboxane A(2) modulates cyclic AMP relaxation and production in human internal mammary artery

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12 December 2020

Regulation of amyloid precursor protein (APP) secretion by protein kinase calpha in human ntera 2 neurons (NT2N).

1 reference

12 December 2020

Cardiovascular responses to the isoprostanes iPF(2alpha)-III and iPE(2)-III are mediated via the thromboxane A(2) receptor in vivo

1 reference

12 December 2020

U-46619, a selective thromboxane A2 mimetic, inhibits the release of endogenous noradrenaline from the rat hippocampus in vitro

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12 December 2020

Isoprostanes, novel markers of oxidative injury, help understanding the pathogenesis of neurodegenerative diseases.

1 reference

12 December 2020

The thromboxane A2 receptor activates mitogen-activated protein kinase via protein kinase C-dependent Gi coupling and Src-dependent phosphorylation of the epidermal growth factor receptor

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12 December 2020

Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease

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12 December 2020

Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

1 reference

12 December 2020

Extracellular-regulated kinase controls beta-amyloid precursor protein mRNA decay

1 reference

12 December 2020

Identification and functional characterization of thromboxane A2 receptors in Schwann cells

1 reference

12 December 2020

Regulation of extracellular signal-regulated kinase cascades by alpha- and beta-isoforms of the human thromboxane A(2) receptor

1 reference

12 December 2020

Increase of brain oxidative stress in mild cognitive impairment: a possible predictor of Alzheimer disease.

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12 December 2020

The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases

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12 December 2020

Presenilins are not required for A beta 42 production in the early secretory pathway.

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12 December 2020

Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease

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12 December 2020

Regulation of amyloid precursor protein expression and secretion via activation of ERK1/2 by hepatocyte growth factor in HEK293 cells transfected with APP751.

1 reference

12 December 2020

Enhanced brain levels of 8,12-iso-iPF2alpha-VI differentiate AD from frontotemporal dementia

1 reference

12 December 2020

The F2-isoprostane, 8-epi-prostaglandin F2 alpha, a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonist

1 reference

12 December 2020

Aging increases amyloid beta-peptide-induced 8-iso-prostaglandin F2alpha release from rat brain

1 reference

12 December 2020

Cell signalling through thromboxane A2 receptors

1 reference

12 December 2020

Amyloid precursor protein mRNA levels in Alzheimer's disease brain

1 reference

12 December 2020

Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia.

1 reference

12 December 2020

Pathways towards and away from Alzheimer's disease

1 reference

12 December 2020

BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo

1 reference

12 December 2020

Thromboxane A receptor-mediated cell proliferation, survival and gene expression in oligodendrocytes

1 reference

12 December 2020

Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease.

1 reference

12 December 2020

Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment.

1 reference

12 December 2020

Involvement of thromboxane receptor in the proatherogenic effect of isoprostane F2alpha-III: evidence from apolipoprotein E- and LDL receptor-deficient mice

1 reference

12 December 2020

Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments

1 reference

12 December 2020

Expression of CD83 is regulated by HuR via a novel cis-active coding region RNA element

1 reference

12 December 2020

Quantitative in vivo biomarkers of oxidative damage and their application to the diagnosis and management of Alzheimer's disease.

1 reference

12 December 2020

Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease

1 reference

12 December 2020

CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling

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12 December 2020

Phenotype associated with APP duplication in five families.

1 reference

12 December 2020

Early exposure to IL-4 stabilizes IL-4 mRNA in CD4+ T cells via RNA-binding protein HuR

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12 December 2020

A hundred years of Alzheimer's disease research

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12 December 2020

FMRP mediates mGluR5-dependent translation of amyloid precursor protein

1 reference

12 December 2020

Expression of APP pathway mRNAs and proteins in Alzheimer's disease

1 reference

12 December 2020

Cloning and expression of cDNA for a human thromboxane A2 receptor

1 reference

12 December 2020

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

1 reference

12 December 2020

Distribution of tau proteins in the normal human central and peripheral nervous system

1 reference

12 December 2020

Inositol 1,4,5-triphosphate-induced granule secretion in platelets. Evidence that the activation of phospholipase C mediated by platelet thromboxane receptors involves a guanine nucleotide binding protein-dependent mechanism distinct from that of th

1 reference

12 December 2020

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

1 reference

12 December 2020

Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease

1 reference

12 December 2020

Amyloid beta protein (A beta) in Alzheimer's disease brain. Biochemical and immunocytochemical analysis with antibodies specific for forms ending at A beta 40 or A beta 42(43).

1 reference

12 December 2020

Purification of rat brain, rabbit aorta, and human platelet thromboxane A2/prostaglandin H2 receptors by immunoaffinity chromatography employing anti-peptide and anti-receptor antibodies

1 reference

12 December 2020

Regulation of amyloid precursor protein release by protein kinase C in Swiss 3T3 fibroblasts

1 reference

12 December 2020

Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome

1 reference

12 December 2020

Amyloids beta40 and beta42 are generated intracellularly in cultured human neurons and their secretion increases with maturation

1 reference

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

12 December 2020

TXA2 agonists inhibit high-voltage-activated calcium channels in rat hippocampal CA1 neurons.

1 reference

12 December 2020

Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation

1 reference

12 December 2020

The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha

1 reference

12 December 2020

Oxidative stress hypothesis in Alzheimer's disease

1 reference

12 December 2020

Central thromboxane receptors: mRNA expression and mediation of pressor responses.

1 reference

12 December 2020

Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

1 reference

12 December 2020

The identification and characterization of oligodendrocyte thromboxane A2 receptors

1 reference

12 December 2020

Cerebrospinal fluid F2-isoprostane levels are increased in Alzheimer's disease.

1 reference

12 December 2020

Increased F2-isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo.

1 reference

12 December 2020

Prostaglandin E2 stimulates amyloid precursor protein gene expression: inhibition by immunosuppressants.

1 reference

12 December 2020

10.1523/JNEUROSCI.0684-08.2008

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670429&resulttype=core&format=json

16 May 2020

1 reference