(Q46629490)

23 December 2017

title

Separation of antiepileptogenic and antiseizure effects of levetiracetam in the spontaneously epileptic rat (SER). (English)

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23 December 2017

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Hai-Dun Yan

1

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23 December 2017

Cai Ji-qun

2

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23 December 2017

Kumatoshi Ishihara

3

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23 December 2017

Takashi Nagayama

4

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23 December 2017

Tadao Serikawa

5

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23 December 2017

Masashi Sasa

6

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23 December 2017

publication date

1 August 2005

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23 December 2017

published in

Epilepsia

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23 December 2017

volume

46

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23 December 2017

issue

8

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23 December 2017

page(s)

1170-1177

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23 December 2017

Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy

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1 reference

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Profile of ucb L059, a novel anticonvulsant drug, in models of partial and generalized epilepsy in mice and rats

21 January 2018

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Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy

21 January 2018

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Levetiracetam does not modulate neuronal voltage-gated Na+ and T-type Ca2+ currents

21 January 2018

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Neurochemical studies with the novel anticonvulsant levetiracetam in mouse brain.

21 January 2018

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The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents

21 January 2018

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Levetiracetam has no significant gamma-aminobutyric acid-related effect on paired-pulse interaction in the dentate gyrus of rats

21 January 2018

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Levetiracetam inhibits the high-voltage-activated Ca(2+) current in pyramidal neurones of rat hippocampal slices

21 January 2018

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Selective blockade of N-type calcium channels by levetiracetam

21 January 2018

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Localization and photoaffinity labelling of the levetiracetam binding site in rat brain and certain cell lines

21 January 2018

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The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam

21 January 2018

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Effects of lamotrigine and levetiracetam on seizure development in a rat amygdala kindling model

21 January 2018

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Bregma, lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight

21 January 2018

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Animal models of epilepsy for the development of antiepileptogenic and disease-modifying drugs. A comparison of the pharmacology of kindling and post-status epilepticus models of temporal lobe epilepsy

21 January 2018

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New horizons in the development of antiepileptic drugs

21 January 2018

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Strategies for identifying and developing new anticonvulsant drugs

21 January 2018

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Current evidence indicates that antiepileptic drugs are anti-ictal, not antiepileptic

21 January 2018

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New strategies for the identification of drugs to prevent the development or progression of epilepsy

21 January 2018

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Current status and future directions in the pharmacotherapy of epilepsy

21 January 2018

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The ideal characteristics of antiepileptic therapy: an overview of old and new AEDs

21 January 2018

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Pharmacological Prophylaxis in the Kindling Model of Epilepsy

21 January 2018

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Drug-mediated neuroprotection and antiepileptogenesis: animal data

21 January 2018

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Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilespy

21 January 2018

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Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials

21 January 2018

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Activation by N-Acetyl-l-Aspartate of Acutely Dissociated Hippocampal Neurons in Rats via Metabotropic Glutamate Receptors

21 January 2018

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The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes

21 January 2018

1 reference

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Isoform-specific, calcium-regulated interaction of the synaptic vesicle proteins SV2 and synaptotagmin

21 January 2018

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Synaptic vesicle protein 2, A new neuroendocrine cell marker

21 January 2018

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Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

21 January 2018

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The antiepileptic drug levetiracetam selectively modifies kindling-induced alterations in gene expression in the temporal lobe of rats

21 January 2018

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The neurobiology of antiepileptic drugs

21 January 2018

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Reduction of voltage-operated potassium currents by levetiracetam: a novel antiepileptic mechanism of action?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.35204.X

Intracellular calcium increase in epileptiform activity: modulation by levetiracetam and lamotrigine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1167.2005.35204.X

10.1111/J.1528-1167.2005.35204.X

21 January 2018

Identifiers

DOI

1 reference

23 December 2017

PubMed ID

16060925

1 reference

23 December 2017