(Q46656402)

24 December 2017

title

Electron cryo-microscopy structure of a human TRPM4 channel (English)

1 reference

24 December 2017

cryogenic electron microscopy

main subject

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Transient receptor potential cation channel subfamily M member 4

1 reference

inorganic cation transmembrane transport

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Paige A Winkler

1

1 reference

24 December 2017

Yihe Huang

2

1 reference

24 December 2017

Weinan Sun

3

1 reference

24 December 2017

Juan Du

4

1 reference

24 December 2017

Wei Lü

5

1 reference

24 December 2017

language of work or name

English

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publication date

6 December 2017

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24 December 2017

published in

Nature

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24 December 2017

volume

552

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24 December 2017

issue

7684

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24 December 2017

page(s)

200-204

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24 December 2017

Voltage dependence of the Ca2+-activated cation channel TRPM4

cites work

1 reference

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7 January 2021

TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization

1 reference

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7 January 2021

Expression, purification, and projection structure by single particle electron microscopy of functional human TRPM4 heterologously expressed in Xenopus laevis oocytes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Heterologously-expressed and Liposome-reconstituted Human Transient Receptor Potential Melastatin 4 Channel (TRPM4) is a Functional Tetramer

1 reference

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7 January 2021

Functional expression of the TRPM4 cationic current in ventricular cardiomyocytes from spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Function and pharmacology of TRPM cation channels

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7 January 2021

The mammalian melastatin-related transient receptor potential cation channels: an overview

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7 January 2021

TRP channels as cellular sensors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

The TRPM ion channel subfamily: molecular, biophysical and functional features.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

TRPM2 Ca2+ permeable cation channels: from gene to biological function

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7 January 2021

Activation of the Ca(2+)-activated nonselective cation channel by diacylglycerol analogues in rat cardiomyocytes

1 reference

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7 January 2021

Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteries

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https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Pharmacological inhibition of TRPM4 hyperpolarizes vascular smooth muscle

1 reference

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7 January 2021

The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Mutational spectrum in the Ca(2+)--activated cation channel gene TRPM4 in patients with cardiac conductance disturbances

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Molecular genetics and functional anomalies in a series of 248 Brugada cases with 11 mutations in the TRPM4 channel

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Trpm4 gene invalidation leads to cardiac hypertrophy and electrophysiological alterations

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

TRPM4 non-selective cation channels influence action potentials in rabbit Purkinje fibres.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

TRPM5 is a voltage-modulated and Ca(2+)-activated monovalent selective cation channel.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Decavanadate modulates gating of TRPM4 cation channels

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Phosphatidylinositol 4,5-bisphosphate rescues TRPM4 channels from desensitization.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

TRPV1 structures in distinct conformations reveal activation mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Structure of the TRPA1 ion channel suggests regulatory mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.

1 reference

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7 January 2021

Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

TRPM4 regulates calcium oscillations after T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

X-ray Crystal Structure of a TRPM Assembly Domain Reveals an Antiparallel Four-stranded Coiled-coil

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

A role of the transient receptor potential domain of vanilloid receptor I in channel gating.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

The selectivity filter of the cation channel TRPM4.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Identification of an aspartic residue in the P-loop of the vanilloid receptor that modulates pore properties

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Structural basis for Ca2+ selectivity of a voltage-gated calcium channel

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

The binding of vanadium (V) oligoanions to sarcoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Antagonistic regulation of native Ca2+- and ATP-sensitive cation channels in brain capillaries by nucleotides and decavanadate

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Automated electron microscope tomography using robust prediction of specimen movements

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Gctf: Real-time CTF determination and correction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

RELION: implementation of a Bayesian approach to cryo-EM structure determination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Frealign: An Exploratory Tool for Single-Particle Cryo-EM.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Features and development of Coot

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Molecular dynamics-based refinement and validation for sub-5 Å cryo-electron microscopy maps

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE24674

7 January 2021

Identifiers

DOI

10.1038/NATURE24674

1 reference

24 December 2017

Dimensions Publication ID

1099658303

0 references

1 reference

24 December 2017