(Q46675964)

24 December 2017

title

Use of Caenorhabditis elegans to evaluate inhibitors of Ras function in vivo (English)

1 reference

24 December 2017

main subject

Caenorhabditis elegans

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David J Reiner

1

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author name string

Vanessa González-Pérez

series ordinal

2

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24 December 2017

Channing J Der

series ordinal

3

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24 December 2017

Adrienne D Cox

series ordinal

4

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24 December 2017

language of work or name

English

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publication date

1 January 2008

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24 December 2017

published in

Methods in Enzymology

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24 December 2017

volume

439

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24 December 2017

page(s)

425-449

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24 December 2017

Pharmacologic inhibitors of MKK1 and MKK2.

cites work

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7 January 2021

Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

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7 January 2021

The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway.

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7 January 2021

Positive and negative regulation of Raf kinase activity and function by phosphorylation

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7 January 2021

Fluoxetine-resistant mutants in C. elegans define a novel family of transmembrane proteins

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7 January 2021

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

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7 January 2021

Specificity and mechanism of action of some commonly used protein kinase inhibitors

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7 January 2021

Raf functions downstream of Ras1 in the Sevenless signal transduction pathway

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7 January 2021

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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7 January 2021

Rules for making human tumor cells

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7 January 2021

Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth

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7 January 2021

Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans

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7 January 2021

The gene lin-3 encodes an inductive signal for vulval development in C. elegans

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7 January 2021

Serotonin and octopamine in the nematode Caenorhabditis elegans

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7 January 2021

The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development

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7 January 2021

A point mutation in the extracellular domain activates LET-23, the Caenorhabditis elegans epidermal growth factor receptor homolog.

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7 January 2021

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

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7 January 2021

Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors

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7 January 2021

Levamisole-resistant mutants of the nematode Caenorhabditis elegans appear to lack pharmacological acetylcholine receptors.

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7 January 2021

The GABAergic nervous system of Caenorhabditis elegans

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Integrating signals from RTKs to ERK/MAPK.

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lin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulval development

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7 January 2021

An activating mutation in sos-1 identifies its Dbl domain as a critical inhibitor of the epidermal growth factor receptor pathway during Caenorhabditis elegans vulval development

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7 January 2021

The epidermal growth factor system in Caenorhabditis elegans

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7 January 2021

Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity

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7 January 2021

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

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7 January 2021

Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling

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7 January 2021

Lately, it occurs to me what a long, strange trip it's been for the farnesyltransferase inhibitors

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7 January 2021

The mighty mouse: genetically engineered mouse models in cancer drug development

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7 January 2021

SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans

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7 January 2021

Maintenance of C. elegans

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7 January 2021

The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

1 reference

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7 January 2021

MAP kinase signaling specificity mediated by the LIN-1 Ets/LIN-31 WH transcription factor complex during C. elegans vulval induction

1 reference

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7 January 2021

KSR, a novel protein kinase required for RAS signal transduction

1 reference

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7 January 2021

Genetic and pharmacological analysis of neurotransmitters controlling egg laying in C. elegans

1 reference

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7 January 2021

10.1016/S0076-6879(07)00430-2

Identifiers

DOI

1 reference

24 December 2017

PubMed ID

18374181

1 reference

24 December 2017