(Q46686083)

24 December 2017

title

Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion (English)

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24 December 2017

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4

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Reinhard Georg Lührmann

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object named as

Reinhard Lührmann

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24 December 2017

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Cindy L Will

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Berthold Kastner

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Henning Urlaub

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24 December 2017

author name string

Cyrille Girard

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24 December 2017

Jianhe Peng

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Ira Lemm

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Klaus Hartmuth

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language of work or name

English

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publication date

1 January 2012

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24 December 2017

published in

Nature Communications

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24 December 2017

volume

3

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24 December 2017

page(s)

994

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24 December 2017

https://scigraph.springernature.com/pub.10.1038/ncomms1998

exact match

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cites work

A guided tour into subcellular colocalization analysis in light microscopy

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Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks.

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Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A

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Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database

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The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region

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Efficient transcription through an intron requires the binding of an Sm-type U1 snRNP with intact stem loop II to the splice donor

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Phosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1

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12 December 2020

Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis

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12 December 2020

Correlation of hnRNP structure and nascent transcript cleavage

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12 December 2020

Molecular architecture of the human Prp19/CDC5L complex

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12 December 2020

A wave of nascent transcription on activated human genes

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12 December 2020

Localization of pre-messenger RNA at discrete nuclear sites

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12 December 2020

Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation

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12 December 2020

The spliceosome: design principles of a dynamic RNP machine

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12 December 2020

Molecular anatomy of a speckle

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12 December 2020

Inefficient processing impairs release of RNA from the site of transcription

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12 December 2020

Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome.

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12 December 2020

Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis

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12 December 2020

Nascent-seq indicates widespread cotranscriptional pre-mRNA splicing in Drosophila

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12 December 2020

Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein

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12 December 2020

The interchromatin granules

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12 December 2020

PP1/PP2A phosphatases are required for the second step of Pre-mRNA splicing and target specific snRNP proteins

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12 December 2020

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts

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12 December 2020

Histone lysine methylation patterns in human cell types are arranged in distinct three-dimensional nuclear zones

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12 December 2020

A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination

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12 December 2020

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

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12 December 2020

Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription.

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12 December 2020

Standardization of northern blot signals by determination of relative poly(A)(+) RNA amounts loaded per lane

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12 December 2020

Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome

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12 December 2020

Distribution of pre-mRNA splicing factors at sites of RNA polymerase II transcription

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12 December 2020

Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes

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12 December 2020

Perichromatin fibrils are in situ forms of nascent transcripts

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12 December 2020

Co-transcriptional splicing of constitutive and alternative exons

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12 December 2020

In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation.

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12 December 2020

Intron-dependent recruitment of pre-mRNA splicing factors to sites of transcription

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12 December 2020

Rapid, diffusional shuttling of poly(A) RNA between nuclear speckles and the nucleoplasm

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12 December 2020

The dynamics of pre-mRNAs and poly(A)+ RNA at speckles in living cells revealed by iFRAP studies.

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12 December 2020

Global Analysis of Nascent RNA Reveals Transcriptional Pausing in Terminal Exons

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12 December 2020

Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method

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12 December 2020

The Dynamics of Chromosome Organization and Gene Regulation

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12 December 2020

Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells

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12 December 2020

Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method

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12 December 2020

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry

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12 December 2020

Rates of in situ transcription and splicing in large human genes

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12 December 2020

In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants

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12 December 2020

Prespliceosomal assembly on microinjected precursor mRNA takes place in nuclear speckles

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12 December 2020

Single-molecule imaging of transcriptionally coupled and uncoupled splicing

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12 December 2020

The intranuclear site of excision of each intron in Balbiani ring 3 pre-mRNA is influenced by the time remaining to transcription termination and different excision efficiencies for the various introns.

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12 December 2020

A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing

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12 December 2020

Phosphorylation and functions of the RNA polymerase II CTD

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12 December 2020

Depletion of SMN by RNA interference in HeLa cells induces defects in Cajal body formation.

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12 December 2020

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12 December 2020

Nuclear localization properties of a conserved protuberance in the Sm core complex

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12 December 2020

Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments

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12 December 2020

The HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicases

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12 December 2020

Ultrastructural analysis of transcription and splicing in the cell nucleus after bromo-UTP microinjection

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12 December 2020

A role for TREX components in the release of spliced mRNA from nuclear speckle domains

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12 December 2020

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS1998

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24 December 2017

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24 December 2017