(Q46686110)

24 December 2017

title

Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts (English)

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24 December 2017

author name string

Burhan I Ghanayem

1

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24 December 2017

L Patrice McDaniel

2

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24 December 2017

Mona I Churchwell

3

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24 December 2017

Nathan C Twaddle

4

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24 December 2017

Rodney Snyder

5

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24 December 2017

Timothy R Fennell

6

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24 December 2017

Daniel R Doerge

7

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24 December 2017

publication date

1 September 2005

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24 December 2017

published in

Toxicological Sciences

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24 December 2017

volume

88

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24 December 2017

issue

2

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24 December 2017

page(s)

311-318

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24 December 2017

Determination of hemoglobin adducts in humans occupationally exposed to acrylamide

cites work

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

Acrylamide is metabolized to glycidamide in the rat: evidence from hemoglobin adduct formation.

21 January 2018

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Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk.

21 January 2018

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Comparison of the hemoglobin adducts formed by administration of N-methylolacrylamide and acrylamide to rats.

21 January 2018

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Metabolism and hemoglobin adduct formation of acrylamide in humans.

21 January 2018

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A Lifetime Oncogenicity Study in Rats with Acrylamide

21 January 2018

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Chemistry, biochemistry, and safety of acrylamide. A review

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

DNA adduct formation from acrylamide via conversion to glycidamide in adult and neonatal mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect

21 January 2018

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Using cytochrome P-450 gene knock-out mice to study chemical metabolism, toxicity, and carcinogenicity

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

DNA adducts, mutations and cancer

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

Acrylamide causes preimplantation abnormalities in embryos and induces chromatin-adducts in male germ cells of mice

21 January 2018

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Chronic toxicity and oncogenicity study on acrylamide incorporated in the drinking water of Fischer 344 rats

21 January 2018

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Analysis of acrylamide in cooked foods by liquid chromatography tandem mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

Hemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile and acrylamide-biomarkers in occupational and environmental medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

Formation of N-7-(2-carbamoyl-2-hydroxyethyl)guanine in DNA of the mouse and the rat following intraperitoneal administration of [14C]acrylamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

"IARC Group 2B carcinogens" reported in cigarette mainstream smoke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

Acrylamide: a comparison of metabolism and hemoglobin adducts in rodents following dermal, intraperitoneal, oral, or inhalation exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

Analysis of acrylamide, a carcinogen formed in heated foodstuffs

21 January 2018

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https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

Effects of acrylamide on rodent reproductive performance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFI307

21 January 2018

Identifiers

DOI

10.1093/TOXSCI/KFI307

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24 December 2017

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24 December 2017