(Q46692515)

24 December 2017

title

Comparison of effects of U18666A and enantiomeric U18666A on sterol synthesis and induction of apoptosis (English)

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24 December 2017

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4

Douglas F Covey

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24 December 2017

author name string

Richard J Cenedella

series ordinal

1

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24 December 2017

Patricia S Sexton

series ordinal

2

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24 December 2017

Kathiresan Krishnan

series ordinal

3

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24 December 2017

publication date

1 June 2005

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24 December 2017

published in

Lipids

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24 December 2017

volume

40

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24 December 2017

issue

6

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24 December 2017

page(s)

635-640

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24 December 2017

https://scigraph.springernature.com/pub.10.1007/s11745-005-1426-9

exact match

0 references

cites work

Induction of chronic epileptiform activity in the rat by an inhibitor of cholesterol synthesis, U18666A

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12 December 2020

Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells

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12 December 2020

Niemann-Pick type C: a disorder of cellular cholesterol trafficking

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12 December 2020

Studies on the mechanism of the epileptiform activity induced by U18666A. II. Concentration, half-life and distribution of radiolabeled U18666A in the brain.

1 reference

12 December 2020

Chronic exposure to U18666A induces apoptosis in cultured murine cortical neurons

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12 December 2020

Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions

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12 December 2020

Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport

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12 December 2020

Direct perturbation of lens membrane structure may contribute to cataracts caused by U18666A, an oxidosqualene cyclase inhibitor

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12 December 2020

Lovastatin exacerbates atypical absence seizures with only minimal effects on brain sterols.

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12 December 2020

Effects of 3 beta-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell cultures

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12 December 2020

Mitochondria and apoptosis

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12 December 2020

Absolute rates of sterol synthesis estimated from [3H]water for bovine lens epithelial cells in culture

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12 December 2020

Inhibitory activity of 8-azadecalin derivatives towards 2,3-oxidosqualene:lanosterol cyclases from baker's yeast and pig's liver

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12 December 2020

Membrane structural changes support the involvement of mitochondria in the bile salt-induced apoptosis of rat hepatocytes.

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12 December 2020

Concentration-dependent effects of AY-9944 and U18666A on sterol synthesis in brain. Variable sensitivities of metabolic steps

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12 December 2020

First synthesis of ent-desmosterol and its conversion to ent-deuterocholesterol

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12 December 2020

The intracellular transport of low density lipoprotein-derived cholesterol is inhibited in Chinese hamster ovary cells cultured with 3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one

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12 December 2020

Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro

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12 December 2020

Crystal structure of a squalene cyclase in complex with the potential anticholesteremic drug Ro48-8071

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12 December 2020

Ro 48-8.071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin.

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12 December 2020

In vitro inhibition of animal and higher plants 2,3-oxidosqualene-sterol cyclases by 2-aza-2,3-dihydrosqualene and derivatives, and by other ammonium-containing molecules

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12 December 2020

Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles

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12 December 2020

Mechanism of cataract production by 3-β(2-diethylaminoethoxy) androst-5-en-17-one hydrochloride, U18666A: An inhibitor of cholesterol biosynthesis

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12 December 2020

Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene−Hopene Cyclase

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12 December 2020

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12 December 2020

Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-treated cells.

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12 December 2020

The enantiomer of cholesterol

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12 December 2020

Posttranscriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in lens epithelial cells by mevalonate-derived nonsterols

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12 December 2020

10.1007/S11745-005-1426-9

Identifiers

DOI

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24 December 2017

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24 December 2017