(Q46711328)

English

Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimally invasive and noninvasive probes for hepatic and first-pass CYP3A activity

scientific article published in October 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimally invasive and noninvasive probes for hepatic and first-pass CYP3A activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

Evan D Kharasch

1

object named as

Evan D Kharasch

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

author name string

Alysa Walker

2

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

Christine Hoffer

3

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

Pamela Sheffels

4

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

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publication date

1 October 2005

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

The Journal of Clinical Pharmacology

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Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

45

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

10

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

1187-1197

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes

1 reference

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The human CYP3A subfamily: practical considerations

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Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

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Genetic contribution to variable human CYP3A-mediated metabolism

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Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7.

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Dietary Effects on Drug Metabolism and Transport

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Factors affecting the clinical development of cytochrome p450 3A substrates

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The erythromycin breath test for the prediction of drug clearance

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Use of the erythromycin breath test for in vivo assessments of cytochrome P4503A activity and dosage individualization

1 reference

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21 January 2018

Concurrent administration of the erythromycin breath test (EBT) and oral midazolam as in vivo probes for CYP3A activity.

1 reference

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Cytochrome P450 3A4 and P-glycoprotein mediate the interaction between an oral erythromycin breath test and rifampin

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Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone

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Physiologic and temporal variation in hepatic elimination of midazolam.

1 reference

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21 January 2018

An evaluation of the suitability of intravenous midazolam as an in vivo marker for hepatic cytochrome P4503A activity

1 reference

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21 January 2018

Influence of food on midazolam absorption.

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21 January 2018

Exercise alters the pharmacokinetics of midazolam

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21 January 2018

Pharmacokinetic-pharmacodynamic modeling of the central nervous system effects of midazolam and its main metabolite alpha-hydroxymidazolam in healthy volunteers.

1 reference

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21 January 2018

Pharmacogenetic determinants of human liver microsomal alfentanil metabolism and the role of cytochrome P450 3A5.

1 reference

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21 January 2018

The relationship between alfentanil distribution kinetics and cardiac output.

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21 January 2018

The role of cytochrome P450 3A4 in alfentanil clearance. Implications for interindividual variability in disposition and perioperative drug interactions.

1 reference

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21 January 2018

A pilot evaluation of alfentanil-induced miosis as a noninvasive probe for hepatic cytochrome P450 3A4 (CYP3A4) activity in humans

1 reference

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21 January 2018

Disposition and miotic effects of oral alfentanil: a potential noninvasive probe for first-pass cytochrome P4503A activity

1 reference

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21 January 2018

Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass cytochrome P450 3A activity: noninvasive assessment by use of pupillary miosis

1 reference

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21 January 2018

Assessment of cytochrome P450 3A4 activity during the menstrual cycle using alfentanil as a noninvasive probe.

1 reference

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21 January 2018

Intraindividual variability in male hepatic CYP3A4 activity assessed by alfentanil and midazolam clearance.

1 reference

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21 January 2018

Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using alfentanil and fexofenadine in combination

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21 January 2018

The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity

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21 January 2018

Normal oxyhemoglobin saturation during sleep. How low does it go?

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21 January 2018

Pharmacokinetics of midazolam and alfentanil in outpatient general anesthesia. A study with concomitant thiopentone, flumazenil or placebo administration

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21 January 2018

CYP3A activity in European American and Japanese men using midazolam as an in vivo probe

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21 January 2018

In vivo comparisons of constitutive cytochrome P450 3A activity assessed by alprazolam, triazolam, and midazolam

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21 January 2018

The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin.

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21 January 2018

Application of semisimultaneous midazolam administration for hepatic and intestinal cytochrome P450 3A phenotyping

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21 January 2018

Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.

1 reference

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21 January 2018

Mathematical procedures in data recording and processing of pupillary fatigue waves

1 reference

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Noninvasive tests of CYP3A enzymes

1 reference

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Identifiers

10.1177/0091270005280077

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

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https://api.fatcat.wiki/v0/release/3v5pztakfveyjiplhmtheg3c7a

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 December 2017

http://europepmc.org/abstract/MED/16172184

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