(Q46711512)

24 December 2017

title

Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease (English)

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24 December 2017

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8

Chi-Huey Wong

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24 December 2017

author name string

Yi-Ming Shao

1

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24 December 2017

Wen-Bin Yang

2

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Tun-Hsun Kuo

3

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Keng-Chang Tsai

4

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24 December 2017

Chun-Hung Lin

5

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24 December 2017

An-Suei Yang

6

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24 December 2017

Po-Huang Liang

7

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language of work or name

English

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publication date

15 February 2008

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24 December 2017

Bioorganic & Medicinal Chemistry

published in

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24 December 2017

volume

16

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issue

8

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24 December 2017

page(s)

4652-4660

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24 December 2017

SARS--beginning to understand a new virus

cites work

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12 December 2020

A novel coronavirus associated with severe acute respiratory syndrome

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12 December 2020

Inhibition of serine proteases by peptidyl fluoromethyl ketones

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12 December 2020

Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease

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12 December 2020

Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes.

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12 December 2020

Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease

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12 December 2020

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

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12 December 2020

Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters

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12 December 2020

Inhibition of cathepsin B by peptidyl aldehydes and ketones: slow-binding behavior of a trifluoromethyl ketone

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12 December 2020

Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV.

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12 December 2020

Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate

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12 December 2020

Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation

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12 December 2020

Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors

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12 December 2020

Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G

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12 December 2020

Development and validation of a genetic algorithm for flexible docking

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12 December 2020

Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors

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12 December 2020

Small molecules targeting severe acute respiratory syndrome human coronavirus

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12 December 2020

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

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12 December 2020

Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro.

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12 December 2020

Mechanism of slow-binding inhibition of human leukocyte elastase by trifluoromethyl ketones.

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12 December 2020

Peptidomimetic inhibitors of the human cytomegalovirus protease.

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12 December 2020

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

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12 December 2020

Design and synthesis of dipeptidyl glutaminyl fluoromethyl ketones as potent severe acute respiratory syndrome coronovirus (SARS-CoV) inhibitors

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12 December 2020

A 3D model of SARS_CoV 3CL proteinase and its inhibitors design by virtual screening.

1 reference

12 December 2020

Characterization of a novel coronavirus associated with severe acute respiratory syndrome

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12 December 2020

Synthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro

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12 December 2020

The Genome sequence of the SARS-associated coronavirus

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12 December 2020

Coronavirus as a possible cause of severe acute respiratory syndrome

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12 December 2020

Synthesis of glutamic acid and glutamine peptides possessing a trifluoromethyl ketone group as SARS-CoV 3CL protease inhibitors

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12 December 2020

10.1016/J.BMC.2008.02.040

Identifiers

DOI

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24 December 2017

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24 December 2017