(Q46718105)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18321038%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18321038%20AND%20SRC:MED&resulttype=core&format=json

quantitative structure-activity relationship

3 January 2020

main subject

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18321038%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Kenneth A. Jacobson

series ordinal

6

1 reference

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3 January 2020

5

Zhan-Guo Gao

1 reference

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3 January 2020

3

Athena M Klutz

1 reference

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3 January 2020

author name string

Andrei A Ivanov

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18321038%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Ben Wang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18321038%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

language of work or name

English

0 references

publication date

6 March 2008

1 reference

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Journal of Medicinal Chemistry

3 January 2020

published in

1 reference

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3 January 2020

volume

51

1 reference

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3 January 2020

issue

7

1 reference

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3 January 2020

page(s)

2088-2099

1 reference

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Synthesis, CoMFA analysis, and receptor docking of 3,5-diacyl-2, 4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists

3 January 2020

cites work

1 reference

12 December 2020

Molecular Field Topology Analysis Method in QSAR Studies of Organic Compounds

1 reference

12 December 2020

Design, synthesis, and evaluation of novel A2A adenosine receptor agonists

1 reference

12 December 2020

N(6)-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting point for searching A(2B) ligands

1 reference

12 December 2020

Current state and perspectives of 3D-QSAR.

1 reference

12 December 2020

CoMFA and homology-based models of the glycine binding site of N-methyl-d-aspartate receptor

1 reference

12 December 2020

A2B adenosine receptor agonists: synthesis and biological evaluation of 2-phenylhydroxypropynyl adenosine and NECA derivatives

1 reference

12 December 2020

Exploring distal regions of the A3 adenosine receptor binding site: sterically constrained N6-(2-phenylethyl)adenosine derivatives as potent ligands.

1 reference

12 December 2020

The study of the mechanism of binding of human ML1A melatonin receptor ligands using molecular modeling

1 reference

12 December 2020

The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure

1 reference

12 December 2020

2-Pyrazolyl-N(6)-substituted adenosine derivatives as high affinity and selective adenosine A(3) receptor agonists

1 reference

12 December 2020

2-Substituted adenosine derivatives: affinity and efficacy at four subtypes of human adenosine receptors

1 reference

12 December 2020

Combined target-based and ligand-based drug design approach as a tool to define a novel 3D-pharmacophore model of human A3 adenosine receptor antagonists: pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives as a key study

1 reference

12 December 2020

Highly diverse, massive organic data as explored by a composite QSPR strategy: an advanced study of boiling point

1 reference

12 December 2020

New pyrazolo[3,4-b]pyridones as selective A(1) adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies

1 reference

12 December 2020

"Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists

1 reference

12 December 2020

Computational modeling approaches to structure-function analysis of G protein-coupled receptors

1 reference

12 December 2020

Molecular modeling and molecular dynamics simulation of the human A2B adenosine receptor. The study of the possible binding modes of the A2B receptor antagonists

1 reference

12 December 2020

Progress in modeling of protein structures and interactions

1 reference

12 December 2020

Autocorrelation of molecular electrostatic potential surface properties combined with partial least squares analysis as alternative attractive tool to generate ligand-based 3D-QSARs

1 reference

12 December 2020

Adenosine receptors as therapeutic targets

1 reference

12 December 2020

Docking studies of agonists and antagonists suggest an activation pathway of the A3 adenosine receptor

1 reference

12 December 2020

Computer aided comparative analysis of the binding modes of the adenosine receptor agonists for all known subtypes of adenosine receptors

1 reference

12 December 2020

Synthesis and biological evaluation of novel 1-deoxy-1-[6-[((hetero)arylcarbonyl)hydrazino]- 9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide derivatives as useful templates for the development of A2B adenosine receptor agonists.

1 reference

12 December 2020

N(6)-[(hetero)aryl/(cyclo)alkyl-carbamoyl-methoxy-phenyl]-(2-chloro)-5'-N-ethylcarboxamido-adenosines: the first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor.

1 reference

12 December 2020

ATP as effector of inorganic pyrophosphatase of Escherichia coli. Identification of the binding site for ATP

1 reference

12 December 2020

The three binding domain model of adenosine receptors: molecular modeling aspects

1 reference

12 December 2020

High-throughput electronic biology: mining information for drug discovery

1 reference

12 December 2020

Three-dimensional quantitative structure-activity relationship of nucleosides acting at the A3 adenosine receptor: analysis of binding and relative efficacy

1 reference

12 December 2020

Cardioprotection by ecto-5'-nucleotidase (CD73) and A2B adenosine receptors

1 reference

12 December 2020

Crystal packing analysis of Rhodopsin crystals

1 reference

12 December 2020

Purine and pyrimidine receptors

1 reference

12 December 2020

Structure-activity relationships of 2,N(6),5'-substituted adenosine derivatives with potent activity at the A2B adenosine receptor.

1 reference

12 December 2020

Adenosine receptor activation ameliorates type 1 diabetes.

1 reference

12 December 2020

Structural investigation of PAP derivatives by CoMFA and CoMSIA reveals novel insight towards inhibition of Bcr-Abl oncoprotein

1 reference

12 December 2020

Probing the binding site of the A1 adenosine receptor reengineered for orthogonal recognition by tailored nucleosides.

1 reference

12 December 2020

P2Y1 antagonists: combining receptor-based modeling and QSAR for a quantitative prediction of the biological activity based on consensus scoring

1 reference

12 December 2020

Distinct structural changes in a G protein-coupled receptor caused by different classes of agonist ligands

1 reference

12 December 2020

New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies

1 reference

12 December 2020

Identification of residues important for agonist recognition and activation in GPR40

1 reference

12 December 2020

Phenylethyl-substituted pyrimido[2,1-f]purinediones and related compounds: Structure–activity relationships as adenosine A1 and A2A receptor ligands

1 reference

12 December 2020

Emerging adenosine receptor agonists

1 reference

12 December 2020

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

1 reference

12 December 2020

1 reference

12 December 2020

Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists

1 reference

12 December 2020

A functional screening of adenosine analogues at the adenosine A2B receptor: a search for potent agonists

1 reference

12 December 2020

Identifiers

DOI

10.1021/JM701442D

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18321038%20AND%20SRC:MED&resulttype=core&format=json

release_d2v3du5xqbes3fdat6yjz3ohbe

3 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/d2v3du5xqbes3fdat6yjz3ohbe

24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18321038%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

PubMed publication ID

18321038

1 reference