(Q46722210)

English

Characterization of a novel filarial serine protease inhibitor, Ov-SPI-1, from Onchocerca volvulus, with potential multifunctional roles during development of the parasite

scientific article published on 26 September 2005

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scholarly article

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

Characterization of a novel filarial serine protease inhibitor, Ov-SPI-1, from Onchocerca volvulus, with potential multifunctional roles during development of the parasite (English)

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

Onchocerca volvulus

object named as

Onchocerca volvulus

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

Steven A Williams

object named as

Steven A Williams

6

0 references

object named as

Mark L Blaxter

7

0 references

8

object named as

Sara Lustigman

1 reference

Europe PubMed Central

24 December 2017

author name string

David B Guiliano

2

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

Yelena Oksov

3

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

Asim K Debnath

4

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

Jing Liu

5

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

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publication date

26 September 2005

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

number of pages

12

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Journal of Biological Chemistry

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

280

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

40845-40856

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

49

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

Molting, enzymes and new targets for chemotherapy of Onchocerca volvulus

1 reference

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Brugia pahangi: identification and characterization of an aminopeptidase associated with larval molting

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21 January 2018

Metalloproteases with EGF, CUB, and thrombospondin-1 domains function in molting of Caenorhabditis elegans

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21 January 2018

A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans

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21 January 2018

Cloning of a cysteine protease required for the molting of Onchocerca volvulus third stage larvae.

1 reference

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21 January 2018

A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases

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21 January 2018

Identification of potential vaccine and drug target candidates by expressed sequence tag analysis and immunoscreening of Onchocerca volvulus larval cDNA libraries

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21 January 2018

Cathepsin L is essential for embryogenesis and development of Caenorhabditis elegans

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21 January 2018

A gene family of cathepsin L-like proteases of filarial nematodes are associated with larval molting and cuticle and eggshell remodeling

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21 January 2018

Anticoagulant repertoire of the hookworm Ancylostoma caninum

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21 January 2018

The isoinhibitors of chymotrypsin/elastase from Ascaris lumbricoides: isolation by affinity chromatography and association with the enzymes.

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21 January 2018

Trichuris suis: A secretory serine protease inhibitor

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21 January 2018

Molecular characterization of Ancylostoma ceylanicum Kunitz-type serine protease inhibitor: evidence for a role in hookworm-associated growth delay.

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21 January 2018

Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa.

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21 January 2018

Molecular characterization of Ancylostoma inhibitors of coagulation factor Xa. Hookworm anticoagulant activity in vitro predicts parasite bloodfeeding in vivo.

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21 January 2018

Serine proteinase inhibitors from nematodes and the arms race between host and pathogen

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21 January 2018

Immune evasion genes from filarial nematodes

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21 January 2018

Modulation of host immune responses by nematode cystatins

1 reference

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21 January 2018

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1 reference

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21 January 2018

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

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21 January 2018

The Pfam protein families database

1 reference

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21 January 2018

SMART 4.0: towards genomic data integration

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21 January 2018

Evolutionary families of peptidase inhibitors

1 reference

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21 January 2018

Genome sequence of the nematode C. elegans: a platform for investigating biology

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21 January 2018

A molecular evolutionary framework for the phylum Nematoda

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21 January 2018

The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase

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21 January 2018

Comparative protein modelling by satisfaction of spatial restraints

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21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

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21 January 2018

Development of a recombinant antigen vaccine against infection with the filarial worm Onchocerca volvulus

1 reference

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21 January 2018

Onchocera volvulus: characterization of a highly immunogenic Gln-rich protein.

1 reference

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21 January 2018

Characterization of an Onchocerca volvulus cDNA clone encoding a genus specific antigen present in infective larvae and adult worms

1 reference

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21 January 2018

RNA interference targeting cathepsin L and Z-like cysteine proteases of Onchocerca volvulus confirmed their essential function during L3 molting

1 reference

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21 January 2018

The Caenorhabditis elegans cathepsin Z-like cysteine protease, Ce-CPZ-1, has a multifunctional role during the worms' development

1 reference

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21 January 2018

Transglutaminase-catalyzed reaction is important for molting of Onchocerca volvulus third-stage larvae

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21 January 2018

On the size of the active site in proteases. I. Papain

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21 January 2018

Expression and characterization of elastase inhibitors from the ascarid nematodes Anisakis simplex and Ascaris suum

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21 January 2018

NEMBASE: a resource for parasitic nematode ESTs

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Anisakis simplex: mutational bursts in the reactive site centers of serine protease inhibitors from an ascarid nematode

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21 January 2018

Trichuris suis: a secretory chymotrypsin/elastase inhibitor with potential as an immunomodulator

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21 January 2018

Primary structure and properties of the cathepsin G/chymotrypsin inhibitor from the larval hemolymph of Apis mellifera.

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21 January 2018

Serine proteinase inhibitor profiles in the hemolymph of a wide range of insect species

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Towards a comprehensive view of the primary structure of venom proteins from the parasitoid wasp Pimpla hypochondriaca

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Precursors of three unique cysteine-rich peptides from the scorpion Buthus martensii Karsch

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Antimicrobial peptides and protease inhibitors in the skin secretions of the crawfish frog, Rana areolata

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A sperm membrane protein that binds in a species-specific manner to the egg extracellular matrix is homologous to von Willebrand factor.

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Nucleotide sequence of pre-pro-von Willebrand factor cDNA.

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21 January 2018

Serine proteases from nematode and protozoan parasites: isolation of sequence homologs using generic molecular probes

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Molecular cloning and characterization of a serine proteinase gene of Trichinella spiralis

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21 January 2018

A putative serine protease among the excretory-secretory glycoproteins of L1 Trichinella spiralis.

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21 January 2018

Onchocerca volvulus: microfilariae secrete elastinolytic and males nonelastinolytic matrix-degrading serine and metalloproteases

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21 January 2018

The bli-4 locus of Caenorhabditis elegans encodes structurally distinct kex2/subtilisin-like endoproteases essential for early development and adult morphology

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A look at the Caenorhabditis elegans Kex2/Subtilisin-like proprotein convertase family

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Cloning and biochemical characterization of blisterase, a subtilisin-like convertase from the filarial parasite, Onchocerca volvulus

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21 January 2018

Functional genomic analysis of C. elegans molting

1 reference

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Extracellular proteases of Onchocerca

1 reference

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21 January 2018

Fluorescently labeled inhibitors detect localized serine protease activities in Drosophila melanogaster pole cells, embryos, and ovarian egg chambers

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21 January 2018

Transcriptional regulation of an unusual trypsin-related protein expressed during insect metamorphosis

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Cuticle degrading proteases from insect moulting fluid and culture filtrates of entomopathogenic fungi

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A Kunitz type protease inhibitor related protein is synthesized in Drosophila prepupal salivary glands and released into the moulting fluid during pupation.

1 reference

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21 January 2018

Expression profiling reveals off-target gene regulation by RNAi

1 reference

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21 January 2018

The genomes of Onchocerca volvulus

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Evolution of enzyme cascades from embryonic development to blood coagulation

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Immunological genomics of Brugia malayi: filarial genes implicated in immune evasion and protective immunity.

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Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.

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Modulation of human T cell responses and macrophage functions by onchocystatin, a secreted protein of the filarial nematode Onchocerca volvulus

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Cystatins of filarial nematodes up-regulate the nitric oxide production of interferon-gamma-activated murine macrophages

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Parasite-Specific Immunomodulatory Functions of Filarial Cystatin

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Litomosoides sigmodontis cystatin acts as an immunomodulator during experimental filariasis

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Bm-CPI-2, a cystatin from Brugia malayi nematode parasites, differs from Caenorhabditis elegans cystatins in a specific site mediating inhibition of the antigen-processing enzyme AEP.

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Nippocystatin, a cysteine protease inhibitor from Nippostrongylus brasiliensis, inhibits antigen processing and modulates antigen-specific immune response

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Serpin expression in the parasitic stages of Trichostrongylus vitrinus, an ovine intestinal nematode

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Serine proteinases of mast cell and leukocyte granules. A league of their own.

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Human autoantibody to defensin: disease association with hyperreactive onchocerciasis (sowda).

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Neutrophil granule proteins: evidence for the participation in the host reaction to skin microfilariae of Onchocerca volvulus after diethylcarbamazine administration

1 reference

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A transcriptomic analysis of the phylum Nematoda

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Identifiers

10.1074/JBC.M504434200

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/16186127

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