(Q46749251)

24 December 2017

title

The mechanism of ageing: primary role of transposable elements in genome disintegration (English)

1 reference

24 December 2017

Ádám Sturm

1

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author name string

Zoltán Ivics

series ordinal

2

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24 December 2017

Tibor Vellai

series ordinal

3

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24 December 2017

publication date

3 April 2015

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24 December 2017

Cellular and Molecular Life Sciences

published in

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24 December 2017

volume

72

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24 December 2017

issue

10

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24 December 2017

page(s)

1839-1847

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24 December 2017

https://scigraph.springernature.com/pub.10.1007/s00018-015-1896-0

exact match

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cites work

The genetics of ageing

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

21 January 2018

The hallmarks of aging

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

The regulation of aging: does autophagy underlie longevity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

A systematic look at an old problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

How does calorie restriction work?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Somatic mutations and ageing in silico

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Rates of behavior and aging specified by mitochondrial function during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Somatic mutations and aging: a re-evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

The telomere hypothesis of cellular aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Telomerase reverse transcriptase delays aging in cancer-resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Uncoupling of longevity and telomere length in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Evolution of the mutation rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Somatic mutations, genome mosaicism, cancer and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Chromatin modifications and their function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Global heterochromatin loss: a unifying theory of aging?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

The heterochromatin loss model of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Genome-wide methylation profiles reveal quantitative views of human aging rates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Impact of aging on DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Aging, cancer and nutrition: the DNA methylation connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Recently mobilized transposons in the human and chimpanzee genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Repetitive elements may comprise over two-thirds of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Initial sequencing and analysis of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Mobilizing diversity: transposable element insertions in genetic variation and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

A unified classification system for eukaryotic transposable elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Small RNAs as guardians of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

21 January 2018

Somatic piRNA biogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

PIWI proteins and PIWI-interacting RNAs in the soma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Small RNAs in transcriptional gene silencing and genome defence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

PIWI-interacting RNAs: from generation to transgenerational epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Epigenetic regulation of an IAP retrotransposon in the aging mouse: progressive demethylation and de-silencing of the element by its repetitive induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Distinct DNA methylomes of newborns and centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Retrotransposition is associated with genome instability during chronological aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Insertion of a foreign nucleotide sequence into mitochondrial DNA causes senescence in Neurospora intermedia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Transcriptional profile of aging in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Age dependence of the copia transposition rate is positively associated with copia transcript abundance in a Drosophila melanogaster isogenic line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Apparent retardation of aging in Drosophila melanogaster by inhibitors of reverse transcriptase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Activation of transposable elements during aging and neuronal decline in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Somatic expression of LINE-1 elements in human tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Somatic retrotransposition alters the genetic landscape of the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

A hypothesis on the role of transposons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Are transposons a cause of ageing?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Mortality patterns suggest lack of senescence in hydra

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Immortality and the base of multicellular life: Lessons from cnidarian stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

PIWI proteins and PIWI-interacting RNAs function in Hydra somatic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

The germ line and somatic stem cell gene Cniwi in the jellyfish Podocoryne carnea

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Planarian regeneration: its end is its beginning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

DjPiwi-1, a member of the PAZ-Piwi gene family, defines a subpopulation of planarian stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Activation of germline-specific genes is required for limb regeneration in the Mexican axolotl

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

The role of senescent cells in ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Morphological and ultrastructural analysis of Turritopsis nutricula during life cycle reversal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-015-1896-0

Are somatic cells inherently deficient in methylation metabolism? A proposed mechanism for DNA methylation loss, senescence and aging.

21 January 2018

1 reference

12 December 2020

Age-dependent somatic excision of transposable element Tc1 in Caenorhabditis elegans

1 reference

12 December 2020

Role of transposable elements in age-related genomic instability

1 reference

12 December 2020

Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

1 reference

12 December 2020

10.1007/S00018-015-1896-0

Identifiers

DOI

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24 December 2017

release_uuv5swqysfchzaxfbxprb5zrie

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Fatcat

https://api.fatcat.wiki/v0/release/uuv5swqysfchzaxfbxprb5zrie

24 November 2022

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24 December 2017