(Q46766704)

25 December 2017

title

SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons (English)

1 reference

25 December 2017

author

Ru-Rong Ji

12

1 reference

25 December 2017

Temugin Berta

Temugin Berta

9

0 references

Qingjian Han

1

Qingjian Han

1 reference

25 December 2017

Mark C. Lay

7

Mark Lay

1 reference

25 December 2017

Wonseok Chang

8

Wonseok Chang

1 reference

25 December 2017

author name string

Yong Ho Kim

2

1 reference

25 December 2017

Xiaoming Wang

3

1 reference

25 December 2017

Di Liu

4

1 reference

25 December 2017

Zhi-Jun Zhang

5

1 reference

25 December 2017

Alexandra L Bey

6

1 reference

25 December 2017

Yan Zhang

10

1 reference

25 December 2017

Yong-Hui Jiang

11

1 reference

25 December 2017

language of work or name

English

0 references

publication date

24 November 2016

1 reference

25 December 2017

published in

Neuron

1 reference

25 December 2017

volume

92

1 reference

25 December 2017

issue

6

1 reference

25 December 2017

page(s)

1279-1293

1 reference

25 December 2017

Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs

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1 reference

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Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.

24 May 2018

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Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration.

24 May 2018

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Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons

24 May 2018

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Shank3 is localized in axons and presynaptic specializations of developing hippocampal neurons and involved in the modulation of NMDA receptor levels at axon terminals

24 May 2018

1 reference

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Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade

24 May 2018

1 reference

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Modeling psychiatric disorders for developing effective treatments

24 May 2018

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Persistent Nociception Triggered by Nerve Growth Factor (NGF) Is Mediated by TRPV1 and Oxidative Mechanisms

24 May 2018

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Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments

24 May 2018

1 reference

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Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice

24 May 2018

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Clinical and genomic evaluation of 201 patients with Phelan-McDermid syndrome

24 May 2018

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Shank mutant mice as an animal model of autism

24 May 2018

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Modeling autism by SHANK gene mutations in mice

24 May 2018

1 reference

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Therapeutic approaches for shankopathies

24 May 2018

1 reference

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The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

24 May 2018

1 reference

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Recent research on aetiology, development and phenomenology of self-injurious behaviour in people with intellectual disabilities: a systematic review and implications for treatment

24 May 2018

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Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1.

24 May 2018

1 reference

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Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

TRPM3 is a nociceptor channel involved in the detection of noxious heat

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Neuronal circuitry for pain processing in the dorsal horn

24 May 2018

1 reference

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24 May 2018

Pain as a channelopathy

1 reference

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Toll-like receptor 7 mediates pruritus

24 May 2018

1 reference

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Transient receptor potential channels: targeting pain at the source

24 May 2018

1 reference

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A-kinase anchoring protein mediates TRPV1 thermal hyperalgesia through PKA phosphorylation of TRPV1

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Inhibition of sodium channel gating by trapping the domain II voltage sensor with protoxin II.

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Contribution of SHANK3 mutations to autism spectrum disorder

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

The menthol receptor TRPM8 is the principal detector of environmental cold

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

An SCN9A channelopathy causes congenital inability to experience pain

24 May 2018

1 reference

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Factors associated with age of diagnosis among children with autism spectrum disorders

24 May 2018

1 reference

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Central sensitization and LTP: do pain and memory share similar mechanisms?

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

24 May 2018

22q13 deletion syndrome

1 reference

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The vanilloid receptor: a molecular gateway to the pain pathway

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Autism spectrum disorders

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

The Shank family of scaffold proteins

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

A capsaicin-receptor homologue with a high threshold for noxious heat

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Bradykinin evoked depolarization of a novel neuroblastoma × DRG neurone hybrid cell line (ND723)

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

How do children with autism spectrum disorders express pain? A comparison with developmentally delayed and typically developing children

24 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Pain sensitivity and observer perception of pain in individuals with autistic spectrum disorder.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

TRPV1 in GABAergic interneurons mediates neuropathic mechanical allodynia and disinhibition of the nociceptive circuitry in the spinal cord.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Sensory abnormalities in autism. A brief report.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Differential regulation of TRP channels in a rat model of neuropathic pain.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Conditional gene deletion in primary nociceptive neurons of trigeminal ganglia and dorsal root ganglia.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Expression of pain in children with autism.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5182147

Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27916453

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEURON.2016.11.007

1 reference

25 December 2017

PMCID

5182147

1 reference

25 December 2017

PubMed ID

27916453

1 reference

25 December 2017