(Q46794658)

25 December 2017

title

Preparation of hybrid (19S-20S-PA28) proteasome complexes and analysis of peptides generated during protein degradation (English)

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25 December 2017

author name string

Paolo Cascio

series ordinal

1

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25 December 2017

Alfred L Goldberg

series ordinal

2

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25 December 2017

language of work or name

English

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publication date

1 January 2005

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25 December 2017

published in

Methods in Enzymology

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25 December 2017

volume

398

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25 December 2017

page(s)

336-352

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25 December 2017

Primary structures of two homologous subunits of PA28, a gamma-interferon-inducible protein activator of the 20S proteasome

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7 January 2021

PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperone

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7 January 2021

The unfolding of substrates and ubiquitin-independent protein degradation by proteasomes

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7 January 2021

ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation

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7 January 2021

Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase

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7 January 2021

The base of the proteasome regulatory particle exhibits chaperone-like activity

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7 January 2021

Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes.

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7 January 2021

26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide

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7 January 2021

Structure and functions of the 20S and 26S proteasomes

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Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity.

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7 January 2021

The pore of activated 20S proteasomes has an ordered 7-fold symmetric conformation

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7 January 2021

The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.

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7 January 2021

A role for the proteasome regulator PA28alpha in antigen presentation

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7 January 2021

A gated channel into the proteasome core particle

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7 January 2021

Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes

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7 January 2021

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7 January 2021

Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes

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7 January 2021

The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation

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7 January 2021

Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates

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7 January 2021

Structure of the proteasome activator REGalpha (PA28alpha)

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7 January 2021

The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release

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7 January 2021

Reconstitution of hybrid proteasomes from purified PA700-20 S complexes and PA28alphabeta activator: ultrastructure and peptidase activities

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7 January 2021

Reconstitution of proteasome activator PA28 from isolated subunits: optimal activity is associated with an alpha,beta-heteromultimer

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7 January 2021

Lysine 188 substitutions convert the pattern of proteasome activation by REGgamma to that of REGs alpha and beta.

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7 January 2021

Molecular dissection of the 11S REG (PA28) proteasome activators

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7 January 2021

Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta.

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7 January 2021

Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome

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7 January 2021

Tissue distribution of constitutive proteasomes, immunoproteasomes, and PA28 in rats

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7 January 2021

The proteasome activator 11 S REG (PA28) and class I antigen presentation

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7 January 2021

Degradation of cell proteins and the generation of MHC class I-presented peptides

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7 January 2021

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases

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https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

The proteasome regulator PA28α/β can enhance antigen presentation without affecting 20S proteasome subunit composition

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

Relative functions of the alpha and beta subunits of the proteasome activator, PA28

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7 January 2021

Two new proteases in the MHC class I processing pathway

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7 January 2021

Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis

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7 January 2021

Molecular properties of the proteasome activator PA28 family proteins and gamma-interferon regulation

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7 January 2021

Ca2+-free calmodulin and calmodulin damaged by in vitro aging are selectively degraded by 26 S proteasomes without ubiquitination.

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7 January 2021

Recognition of the polyubiquitin proteolytic signal

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7 January 2021

Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28

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7 January 2021

Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

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7 January 2021

A proteasome howdunit: the case of the missing signal

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https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

The 26S proteasome: a molecular machine designed for controlled proteolysis

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https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

Structural basis for the activation of 20S proteasomes by 11S regulators

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

Two distinct pathways mediated by PA28 and hsp90 in major histocompatibility complex class I antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

In vivo assembly of the proteasomal complexes, implications for antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2805%2998028-2

7 January 2021

10.1016/S0076-6879(05)98028-2

Identifiers

DOI

1 reference

25 December 2017

1 reference

25 December 2017