(Q46806998)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PierFranco Spano

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Marina Pizzi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

I Sarnico

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

F Boroni

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

M Benarese

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

M Alghisi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

L Battistin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

publication date

16 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neural Transmission

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

693-701

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18197358%20AND%20SRC:MED&resulttype=core&format=json

Global ischemia activates nuclear factor-kappa B in forebrain neurons of rats

1 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00702-007-0016-1

IKK2 inhibitor alleviates kidney and wasting diseases in a murine model of human AIDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-007-0016-1

Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-007-0016-1

Attenuation of excitatory amino acid toxicity by metabotropic glutamate receptor agonists and aniracetam in primary cultures of cerebellar granule cells

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS00702-007-0016-1

21 January 2018

12 December 2020

Interleukin-10 prevents glutamate-mediated cerebellar granule cell death by blocking caspase-3-like activity.

1 reference

12 December 2020

Glutamate and the pathophysiology of hypoxic--ischemic brain damage

1 reference

12 December 2020

Long-term hippocampal slices: a model system for investigating synaptic mechanisms and pathologic processes

1 reference

12 December 2020

Activation of AP-1 and Nuclear Factor-κB Transcription Factors Is Involved in Hydrogen Peroxide-Induced Apoptotic Cell Death of Olligodendrocytes

1 reference

12 December 2020

Nuclear factor-kappaB activation by reactive oxygen species mediates voltage-gated K+ current enhancement by neurotoxic beta-amyloid peptides in nerve growth factor-differentiated PC-12 cells and hippocampal neurones

1 reference

12 December 2020

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

1 reference

12 December 2020

Neuronal and glial apoptosis after traumatic spinal cord injury.

1 reference

12 December 2020

Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth

1 reference

12 December 2020

Regulation of beta-catenin function by the IkappaB kinases

1 reference

12 December 2020

The inhibitor of I kappa B alpha phosphorylation BAY 11-7082 prevents NMDA neurotoxicity in mouse hippocampal slices.

1 reference

12 December 2020

NF-kappaB is activated and promotes cell death in focal cerebral ischemia

1 reference

12 December 2020

IKK mediates ischemia-induced neuronal death

1 reference

12 December 2020

Opposing roles for NF-kappa B/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1beta

1 reference

12 December 2020

Induction of tumor suppressor p53 and DNA fragmentation in organotypic hippocampal cultures following excitotoxin treatment

1 reference

12 December 2020

Nuclear factor kappaB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striatum

1 reference

12 December 2020

Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia.

1 reference

12 December 2020

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Neurodegeneration

1 reference

12 December 2020

Metabotropic and ionotropic transducers of glutamate signal inversely control cytoplasmic Ca2+ concentration and excitotoxicity in cultured cerebellar granule cells: pivotal role of protein kinase C.

1 reference

12 December 2020

Ischemic damage and subsequent proliferation of oligodendrocytes in focal cerebral ischemia

1 reference

12 December 2020

NF-kappaB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity.

1 reference

12 December 2020

Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice.

1 reference

12 December 2020

Glutamate excitotoxicity in a model of multiple sclerosis

1 reference

12 December 2020

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

1 reference

12 December 2020

NF-kappaB pathway: a target for preventing beta-amyloid (Abeta)-induced neuronal damage and Abeta42 production

1 reference

12 December 2020

Spatiotemporal evidence of apoptosis-mediated ischemic injury in organotypic hippocampal slice cultures

1 reference

12 December 2020

Neuronal activation of NF-kappaB contributes to cell death in cerebral ischemia

1 reference

12 December 2020

AS602868, a pharmacological inhibitor of IKK2, reveals the apoptotic potential of TNF-alpha in Jurkat leukemic cells

1 reference

12 December 2020

Novel injury mechanism in anoxia and trauma of spinal cord white matter: glutamate release via reverse Na+-dependent glutamate transport.

1 reference

12 December 2020

Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.

1 reference

12 December 2020

The link between excitotoxic oligodendroglial death and demyelinating diseases

1 reference

12 December 2020

Multiple sclerosis: altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage

1 reference

12 December 2020

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

1 reference

12 December 2020

Nuclear factor-kappaB contributes to infarction after permanent focal ischemia

1 reference

12 December 2020

Inhibition of nuclear factor kappaB is associated with neuroprotective effects of glycyrrhizic acid on glutamate-induced excitotoxicity in primary neurons.

1 reference

12 December 2020

NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo

1 reference

12 December 2020

Targeting NF-kappaB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells.

1 reference

12 December 2020

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

1 reference

12 December 2020

Nuclear factor-kappa B decoy attenuates neuronal damage after global brain ischemia: a future strategy for brain protection during circulatory arrest

1 reference

12 December 2020

Prevention of neuron and oligodendrocyte degeneration by interleukin-6 (IL-6) and IL-6 receptor/IL-6 fusion protein in organotypic hippocampal slices

1 reference

12 December 2020

Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity.

1 reference

12 December 2020

Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity

1 reference

12 December 2020

Inhibition of IkappaBalpha phosphorylation prevents glutamate-induced NF-kappaB activation and neuronal cell death.

1 reference

12 December 2020

Shaping the nuclear action of NF-kappaB

1 reference

12 December 2020

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway

1 reference

12 December 2020

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

1 reference

12 December 2020

The IKK NF-kappa B system: a treasure trove for drug development

1 reference

12 December 2020

Regulation of expression of nuclear factor kappa B RelA in oligodendrocytes: effect of hypoxia

1 reference

12 December 2020

Signaling to NF-kappaB

1 reference

12 December 2020

Autoimmune encephalomyelitis ameliorated by AMPA antagonists

1 reference

12 December 2020

Cell death in models of spinal cord injury

1 reference

12 December 2020