(Q46876173)

26 December 2017

title

T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus (English)

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26 December 2017

author name string

T J Hagenbeek

series ordinal

1

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26 December 2017

H Spits

series ordinal

2

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26 December 2017

publication date

29 November 2007

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26 December 2017

published in

Leukemia

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26 December 2017

volume

22

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26 December 2017

issue

3

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26 December 2017

page(s)

608-619

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26 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2405056

exact match

0 references

cites work

Regulated costimulation in the thymus is critical for T cell development: dysregulated CD28 costimulation can bypass the pre-TCR checkpoint

1 reference

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T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

21 January 2018

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Phosphoinositide 3-kinase: diverse roles in immune cell activation

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

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Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells

21 January 2018

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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The role of interleukin-7 in early T-cell development.

21 January 2018

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Essential requirement for c-kit and common gamma chain in thymocyte development cannot be overruled by enforced expression of Bcl-2.

21 January 2018

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Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

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Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus

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Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: a critical role for the beta chain in development

21 January 2018

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Pleiotropic changes controlled by the pre-T-cell receptor

21 January 2018

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An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors

21 January 2018

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CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity

21 January 2018

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

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Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

21 January 2018

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Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.

21 January 2018

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The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling

21 January 2018

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Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 January 2018

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Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

21 January 2018

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Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells.

21 January 2018

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Identification of the tumor cells in peripheral T-cell lymphomas by combined polymerase chain reaction-based T-cell receptor beta spectrotyping and immunohistological detection with T-cell receptor beta chain variable region segment-specific antibod

21 January 2018

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A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

21 January 2018

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Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation

21 January 2018

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Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

21 January 2018

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Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival

21 January 2018

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Lck activity controls CD4/CD8 T cell lineage commitment.

21 January 2018

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Phosphatidylinositol 3-kinase regulates the CD4/CD8 T cell differentiation ratio

21 January 2018

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Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus

21 January 2018

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Genetic background controls tumor development in PTEN-deficient mice.

21 January 2018

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PTEN and myotubularin: novel phosphoinositide phosphatases

21 January 2018

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Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells

21 January 2018

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Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.

21 January 2018

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Modeling and analysis on the internal impact of a Stewart platform utilized for spacecraft docking

21 January 2018

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High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

21 January 2018

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Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors

21 January 2018

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7 January 2021

Unequal Contribution of Akt Isoforms in the Double-Negative to Double-Positive Thymocyte Transition

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7 January 2021

Control of pre-T cell proliferation and differentiation by the GTPase Rac-1

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7 January 2021

Impaired Fas response and autoimmunity in Pten+/- mice

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7 January 2021

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2405056

7 January 2021

CD44: structure, function, and association with the malignant process.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2405056

7 January 2021

PTEN and p53: who will get the upper hand?

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2405056

7 January 2021

NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2405056

1 reference

26 December 2017

Dimensions Publication ID

1019003933

0 references

Fatcat ID

release_yr63gi5ldjae5fm3ut5ekwxami

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yr63gi5ldjae5fm3ut5ekwxami

24 November 2022

mapped directly with Wikidata item

1 reference

26 December 2017