(Q46903411)

26 December 2017

title

Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2. (English)

1 reference

26 December 2017

main subject

hypoxia

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author

Christopher J. Schofield

series ordinal

2

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26 December 2017

Peter J. Ratcliffe

series ordinal

3

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26 December 2017

Kirsty S Hewitson

series ordinal

1

object named as

Kirsty S Hewitson

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26 December 2017

language of work or name

English

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publication date

1 January 2007

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26 December 2017

published in

Methods in Enzymology

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26 December 2017

volume

435

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26 December 2017

page(s)

25-42

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26 December 2017

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Regulation of the Drosophila bHLH-PAS protein Sima by hypoxia: functional evidence for homology with mammalian HIF-1 alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Dioxygen activation at mononuclear nonheme iron active sites: enzymes, models, and intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Assay of prolyl 4-hydroxylase by the chromatographic determination of [14C]succinic acid on ion-exchange minicolumns

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

FeII/alpha-ketoglutarate-dependent hydroxylases and related enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Mammalian EGLN genes have distinct patterns of mRNA expression and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Studies on the active site of deacetoxycephalosporin C synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Quantitative determination of free intracellular α-keto acids in neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Structure-function analysis of phytanoyl-CoA 2-hydroxylase mutations causing Refsum's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Regulation of angiogenesis by hypoxia: role of the HIF system

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Studies on the specificity of unprocessed and mature forms of phytanoyl-CoA 2-hydroxylase and mutation of the iron binding ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

A high-performance liquid chromatography assay for threonine/serine dehydratase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Determination and comparison of specific activity of the HIF-prolyl hydroxylases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Structure of a cephalosporin synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

The selectivity and inhibition of AlkB.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935002-7

7 January 2021

10.1016/S0076-6879(07)35002-7

Identifiers

DOI

1 reference

26 December 2017

1 reference

26 December 2017