(Q46909156)

26 December 2017

title

Fragmental modeling of human glutamate transporter EAAT1 and analysis of its binding modes by docking and pharmacophore mapping (English)

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26 December 2017

author

Laura De Luca

2

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26 December 2017

Giulio Vistoli

4

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26 December 2017

Alessandro Pedretti

1

object named as

Alessandro Pedretti

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26 December 2017

author name string

Cristina Sciarrillo

3

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26 December 2017

publication date

1 January 2008

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26 December 2017

published in

ChemMedChem

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26 December 2017

volume

3

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26 December 2017

issue

1

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26 December 2017

page(s)

79-90

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26 December 2017

Ligands for glutamate receptors: design and therapeutic prospects

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Diversity of glutamate transporter expression and function in the mammalian retina

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Distribution of the glutamate transporters GLT-1 (SLC1A2) and GLAST (SLC1A3) in peripheral organs

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Accessing a transporter structure

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A model for the topology of excitatory amino acid transporters determined by the extracellular accessibility of substituted cysteines

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7 January 2021

Identification of functional domains of the human glutamate transporters EAAT1 and EAAT2.

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7 January 2021

Functional analysis of the high affinity, Na(+)-dependent glutamate transporter GLAST-1 by site-directed mutagenesis

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7 January 2021

A reentrant loop domain in the glutamate carrier EAAT1 participates in substrate binding and translocation

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7 January 2021

Sulfhydryl modification of V449C in the glutamate transporter EAAT1 abolishes substrate transport but not the substrate-gated anion conductance

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Structural rearrangements at the translocation pore of the human glutamate transporter, EAAT1

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Construction of human ghrelin receptor (hGHS-R1a) model using a fragmental prediction approach and validation through docking analysis

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Modeling of human ghrelin receptor (hGHS-R1a) in its close state and validation by molecular docking

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7 January 2021

A conserved serine-rich stretch in the glutamate transporter family forms a substrate-sensitive reentrant loop

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7 January 2021

Cysteine-scanning mutagenesis reveals a conformationally sensitive reentrant pore-loop in the glutamate transporter GLT-1.

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7 January 2021

Cysteine-scanning mutagenesis reveals a highly amphipathic, pore-lining membrane-spanning helix in the glutamate transporter GltT.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Analysis of the full-length integrase–DNA complex by a modified approach for DNA docking

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7 January 2021

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

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7 January 2021

Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1'S,2'R)-2-(carboxycyclopropyl)glycine (L-CCG III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy

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7 January 2021

Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers

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7 January 2021

Characterization of novel L-threo-beta-benzyloxyaspartate derivatives, potent blockers of the glutamate transporters

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7 January 2021

Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT2.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700197

7 January 2021

Synthesis and biological activities of aryl-ether-, biaryl-, and fluorene-aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT-2.

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https://api.crossref.org/works/10.1002%2FCMDC.200700197

7 January 2021

A fast flexible docking method using an incremental construction algorithm.

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https://api.crossref.org/works/10.1002%2FCMDC.200700197

7 January 2021

Identification of common functional configurations among molecules

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https://api.crossref.org/works/10.1002%2FCMDC.200700197

7 January 2021

Identifiers

DOI

10.1002/CMDC.200700197

1 reference

26 December 2017

1 reference

26 December 2017