(Q46922851)

English

Pharmacodynamics of carbamazepine-mediated induction of CYP3A4, CYP1A2, and Pgp as assessed by probe substrates midazolam, caffeine, and digoxin

scientific article published on 31 October 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

Pharmacodynamics of carbamazepine-mediated induction of CYP3A4, CYP1A2, and Pgp as assessed by probe substrates midazolam, caffeine, and digoxin (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

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1 reference

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pharmacodynamics

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author name string

Magnusson MO

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

Dahl ML

2

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

Cederberg J

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

Karlsson MO

4

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

Sandström R

5

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

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publication date

31 October 2007

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

Clinical Pharmacology & Therapeutics

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

84

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

52-62

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

Measurement of protein turnover in rat liver. Analysis of the complex curve for decay of label in a mixture of proteins

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The use of caffeine for enzyme assays: a critical appraisal

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Kinetics and metabolism of carbamazepine during combined antiepileptic drug therapy

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Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine and theophylline in man.

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Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans.

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The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

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P-glycoprotein-mediated intestinal and biliary digoxin transport in humans

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Kinetic models of induction: I. Persistence of the inducing substance

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Transcriptional profiling of genes induced in the livers of patients treated with carbamazepine

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Carbamazepine metabolism in man. Induction and pharmacogenetic aspects

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The human intestinal cytochrome P450 "pie".

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Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

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Limited sampling models for oral midazolam: midazolam plasma concentrations, not the ratio of 1-hydroxymidazolam to midazolam plasma concentrations, accurately predicts AUC as a biomarker of CYP3A activity

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A rapid and sensitive LC/MS/MS assay for quantitative determination of digoxin in rat plasma

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Identifiers

10.1038/SJ.CLPT.6100431

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/17971810

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