(Q46944498)

26 December 2017

title

Curcumin-derived pyrazoles and isoxazoles: Swiss army knives or blunt tools for Alzheimer's disease? (English)

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26 December 2017

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9

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26 December 2017

Eckhard Mandelkow

8

object named as

Eckhard Mandelkow

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26 December 2017

Rajeshwar Narlawar

1

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26 December 2017

Marcus Pickhardt

2

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26 December 2017

Stefanie Leuchtenberger

3

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26 December 2017

Karlheinz Baumann

4

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26 December 2017

Sabine Krause

5

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26 December 2017

Thomas Dyrks

6

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26 December 2017

Sascha Weggen

7

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26 December 2017

publication date

1 January 2008

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26 December 2017

published in

ChemMedChem

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26 December 2017

volume

3

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26 December 2017

issue

1

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26 December 2017

page(s)

165-172

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26 December 2017

Drug development and PET-diagnostics for Alzheimer's disease.

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γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

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Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain

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A potential role of the curry spice curcumin in Alzheimer's disease

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7 January 2021

Curcuminoids as potent inhibitors of lipid peroxidation

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7 January 2021

Strategy and planning for chemopreventive drug development: clinical development plans II.

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7 January 2021

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Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

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7 January 2021

Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models.

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7 January 2021

Curcumin derivatives inhibit or modulate beta-amyloid precursor protein metabolism.

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7 January 2021

Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents

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Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation

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Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets

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7 January 2021

Lithium decreases secretion of Abeta1-42 and C-truncated species Abeta1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta1-38.

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7 January 2021

Scaffold of the cyclooxygenase-2 (COX-2) inhibitor carprofen provides Alzheimer gamma-secretase modulators.

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7 January 2021

N-Substituted carbazolyloxyacetic acids modulate Alzheimer associated gamma-secretase.

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7 January 2021

Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells

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7 January 2021

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7 January 2021

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7 January 2021

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Identifiers

DOI

10.1002/CMDC.200700218

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26 December 2017

1 reference

26 December 2017