(Q46955937)

English

Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha

scientific article published on 21 February 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

author name string

Ji Miao

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

Sungsoon Fang

2

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

Yangjin Bae

3

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

Jongsook Kim Kemper

4

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

language of work or name

0 references

publication date

21 February 2006

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

281

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

21

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

14537-14546

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Coordinate transcriptional regulation of bile acid homeostasis and drug metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Bile acid regulation of gene expression: roles of nuclear hormone receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1 alpha. A possible link between xenobiotic response and nutritional state

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Role of accessory factors and steroid receptor coactivator 1 in the regulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Control of pancreas and liver gene expression by HNF transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Association between hepatocyte nuclear factor 6 (HNF-6) and FoxA2 DNA binding domains stimulates FoxA2 transcriptional activity but inhibits HNF-6 DNA binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Role of an mSin3A-Swi/Snf chromatin remodeling complex in the feedback repression of bile acid biosynthesis by SHP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Orphan nuclear receptor small heterodimer partner represses hepatocyte nuclear factor 3/Foxa transactivation via inhibition of its DNA binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Effects of phenobarbital and 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene on differentiated functions in mouse liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Inhibition of gluconeogenesis in isolated rat hepatocytes after chronic treatment with phenobarbital

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510713200

21 January 2018

Identifiers

10.1074/JBC.M510713200

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/16492670

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