(Q46981944)

English

A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat.

scientific article published on 15 March 2006

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat. (English)

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

pharmacokinetics

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author name string

Mats O Magnusson

1

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

Mats O Karlsson

2

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

Rikard Sandström

3

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

publication date

15 March 2006

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

Pharmaceutical Research

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

23

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

3

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

521-532

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

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Genetic regulation of UDP-glucuronosyltransferase induction by polycyclic aromatic compounds in mice. Co-segregation with aryl hydrocarbon (benzo(alpha)pyrene) hydroxylase induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

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A semiphysiological pharmacokinetic model for artemisinin in healthy subjects incorporating autoinduction of metabolism and saturable first-pass hepatic extraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

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A mechanistic approach to antiepileptic drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Foreign compound metabolism in the liver.

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https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interpulse interval in circulating growth hormone patterns regulates sexually dimorphic expression of hepatic cytochrome P450.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

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Enzyme induction in the cytochrome P-450 system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

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Dose-dependence and repeated-dose studies for receptor/gene-mediated pharmacodynamics of methylprednisolone on glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

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The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

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Pharmacokinetic interactions between antiepileptic drugs. Clinical considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course of enzyme induction in liver and kidneys and absorption, distribution and elimination of 1,4-dichlorobenzene in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

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Preparation and characterization of subcellular fractions from the liver of C57B1/6 mice, with special emphasis on their suitability for use in studies of epoxide hydrolase activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

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Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanism-based pharmacokinetic-enzyme model for cyclophosphamide autoinduction in breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fast determination of low-level cytochrome P-450 1A1 activity by high-performance liquid chromatography with fluorescence or visible absorbance detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regioselectivity and stereoselectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbital-induced rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of hepatic microsomal cytochrome P-450.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isozyme specificity of testosterone 7 alpha-hydroxylation in rat hepatic microsomes: is cytochrome P-450a the sole catalyst?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenobarbital N-glucosylation by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

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Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of eight testosterone metabolites using column switching and liquid chromatography/tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The in vivo turnover of rat liver microsomal epoxide hydrolase and both the apoprotein and heme moieties of specific cytochrome P-450 isozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

40 Induction of cytochromes P450IA1 and P450IA2 and measurement of catalytic activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of androstenedione formation from testosterone and epitestosterone catalyzed by purified cytochrome P-450b

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of felbamate on the pharmacokinetics of phenobarbital

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-steady state population kinetics of intravenous phenytoin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

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Time-Dependent Kinetics IV: Pharmacokinetic Theory of Enzyme Induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course of enzyme induction in humans: effect of pentobarbital on nortriptyline metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16525862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-005-9571-Z

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16525862

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