(Q46982143)

English

Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia

scientific article published on 24 September 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

Inhibition of human dimethylarginine dimethylaminohydrolase-1 by S-nitroso-L-homocysteine and hydrogen peroxide. Analysis, quantification, and implications for hyperhomocysteinemia (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

author name string

Lin Hong

1

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

Walter Fast

2

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

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publication date

24 September 2007

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

282

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

48

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

34684-34692

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

Blocking NO synthesis: how, where and why?

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Asymmetric dimethylarginine (ADMA) and cardiovascular disease: insights from prospective clinical trials

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Homocysteine and redox signaling

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ADMA and hyperhomocysteinemia

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Selective substrate-based inhibitors of mammalian dimethylarginine dimethylaminohydrolase.

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Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis

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Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors.

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A continuous spectrophotometric assay for dimethylarginine dimethylaminohydrolase

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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Characterization of a transient covalent adduct formed during dimethylarginine dimethylaminohydrolase catalysis

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Structural and functional characterization of the Zn(II) site in dimethylargininase-1 (DDAH-1) from bovine brain. Zn(II) release activates DDAH-1.

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21 January 2018

A novel superfamily of enzymes that catalyze the modification of guanidino groups.

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Protein arginine deiminase 4: evidence for a reverse protonation mechanism

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Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

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21 January 2018

Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis

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21 January 2018

Searching for DDAH inhibitors: S-nitroso-L-homocysteine is a chemical lead

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21 January 2018

Protein-sulfenic acids: diverse roles for an unlikely player in enzyme catalysis and redox regulation

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Oxidation and generation of hydrogen peroxide by thiol compounds in commonly used cell culture media

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Compartmentation of glutathione: implications for the study of toxicity and disease.

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Kinetics and mechanism of the reaction of cysteine and hydrogen peroxide in aqueous solution

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21 January 2018

Molecular basis of homocysteine toxicity in humans.

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21 January 2018

Equilibrium and kinetics studies of transnitrosation between S-nitrosothiols and thiols

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21 January 2018

Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen

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21 January 2018

S-Nitrosothiols: cellular formation and transport

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21 January 2018

Disruption of methylarginine metabolism impairs vascular homeostasis

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21 January 2018

Specific reactions of S-nitrosothiols with cysteine hydrolases: A comparative study between dimethylargininase-1 and CTP synthetase

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21 January 2018

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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Purification, cDNA cloning and expression of human NG,NG-dimethylarginine dimethylaminohydrolase

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Characterization of dimethylargininase from bovine brain: evidence for a zinc binding site.

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Interaction with substrate sensitises caspase-3 to inactivation by hydrogen peroxide.

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Catalytic and chemical competence of regulation of cdc25 phosphatase by oxidation/reduction

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Regulation of PTP1B via glutathionylation of the active site cysteine 215

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Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine

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Identifiers

10.1074/JBC.M707231200

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/17895252

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