(Q47146669)

9 January 2018

title

Combining Vγ9Vδ2 T Cells with a Lipophilic Bisphosphonate Efficiently Kills Activated Hepatic Stellate Cells (English)

1 reference

9 January 2018

Xiaoyu Hu

8

0 references

author name string

Xiaoying Zhou

1

1 reference

9 January 2018

Yanzheng Gu

2

1 reference

9 January 2018

Hongying Xiao

3

1 reference

9 January 2018

Ning Kang

4

1 reference

9 January 2018

Yonghua Xie

5

1 reference

9 January 2018

Guangbo Zhang

6

1 reference

9 January 2018

Yan Shi

7

1 reference

9 January 2018

Eric Oldfield

9

1 reference

9 January 2018

Xueguang Zhang

10

1 reference

9 January 2018

Yonghui Zhang

11

1 reference

9 January 2018

publication date

24 October 2017

1 reference

9 January 2018

published in

Frontiers in Immunology

1 reference

9 January 2018

volume

8

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9 January 2018

page(s)

1381

1 reference

9 January 2018

Strong adhesion by regulatory T cells induces dendritic cell cytoskeletal polarization and contact-dependent lethargy.

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Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity

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Sensing of Pyrophosphate Metabolites by Vγ9Vδ2 T Cells.

23 May 2018

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The Vγ9Vδ2 T Cell Antigen Receptor and Butyrophilin-3 A1: Models of Interaction, the Possibility of Co-Evolution, and the Case of Dendritic Epidermal T Cells

23 May 2018

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A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin

23 May 2018

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Targeted activation of human Vγ9Vδ2-T cells controls epstein-barr virus-induced B cell lymphoproliferative disease

23 May 2018

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The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human Vγ9Vδ2 T Cells

23 May 2018

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γδ T cells and their potential for immunotherapy

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Hepatic stellate cells and liver fibrosis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

Decreased Vδ2 γδ T cells associated with liver damage by regulation of Th17 response in patients with chronic hepatitis B.

23 May 2018

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Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human Vγ2Vδ2 T cells

23 May 2018

1 reference

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Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice.

23 May 2018

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Six-of-the-best: unique contributions of γδ T cells to immunology

23 May 2018

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Characterization of human γδ T lymphocytes infiltrating primary malignant melanomas

23 May 2018

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The Molecular Basis for Modulation of Human V 9V 2 T Cell Responses by CD277/Butyrophilin-3 (BTN3A)-specific Antibodies

23 May 2018

1 reference

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Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset

23 May 2018

1 reference

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Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity

23 May 2018

1 reference

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Fibrosis-dependent mechanisms of hepatocarcinogenesis

23 May 2018

1 reference

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Clinical evaluation of autologous gamma delta T cell-based immunotherapy for metastatic solid tumours

23 May 2018

1 reference

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The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice

23 May 2018

1 reference

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Bisphosphonates: the first 40 years

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity

23 May 2018

1 reference

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Thermodynamics of bisphosphonates binding to human bone: a two-site model

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells

23 May 2018

1 reference

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Current and future anti-fibrotic therapies for chronic liver disease

23 May 2018

1 reference

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Targeting human {gamma}delta} T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer

23 May 2018

1 reference

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Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells

23 May 2018

1 reference

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V gamma 9V delta 2 T cell response to colon carcinoma cells

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

In vitro cytotoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

Adoptive immunotherapy for advanced non-small cell lung cancer using zoledronate-expanded γδTcells: a phase I clinical study.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

Decrease in CD3-negative-CD8dim(+) and Vdelta2/Vgamma9 TcR+ peripheral blood lymphocyte counts, low perforin expression and the impairment of natural killer cell activity is associated with chronic hepatitis C virus infection.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

Highly potent geminal bisphosphonates. From pamidronate disodium (Aredia) to zoledronic acid (Zometa).

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5661056

?Sternzellen? in the liver: Perisinusoidal cells with special reference to storage of vitamin A

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29118758

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanical interactions between dendritic cells and T cells correlate with T cell responsiveness

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29118758

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FIMMU.2017.01381

1 reference

9 January 2018

PMCID

5661056

1 reference

9 January 2018

PubMed ID

29118758

1 reference

9 January 2018