(Q47148137)

http://europepmc.org/abstract/PMC/5703854

9 January 2018

title

Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism (English)

1 reference

http://europepmc.org/abstract/PMC/5703854

9 January 2018

author

Gyorgy Szabadkai

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Benoit Bilanges

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Gaetan Chicanne

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Lucy Collinson

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Essam Ghazaly

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Shankar Srinivas

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Cheryl Scudamore

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

28

Bart Vanhaesebroeck

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Samira Alliouachene

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Wayne Pearce

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Daniele Morelli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Yuen-Li Chung

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Colin Valet

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Julia M Hill

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Peter J Voshol

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Christopher Peddie

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Khaled Ali

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Vinothini Rajeeve

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Georgios Trichas

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Claire Chaussade

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Rachel S Salamon

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jonathan M Backer

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Maria A Whitehead

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Erin P Keaney

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Leon O Murphy

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Robert K Semple

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Bernard Payrastre

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Sharon A Tooze

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

27 November 2017

1 reference

http://europepmc.org/abstract/PMC/5703854

9 January 2018

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

1804

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

10 June 2020

copyright license

start time

27 November 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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23 May 2018

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Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity

23 May 2018

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23 May 2018

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mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival

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Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

23 May 2018

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Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

23 May 2018

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Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

23 May 2018

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Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer

23 May 2018

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23 May 2018

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Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis

23 May 2018

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23 May 2018

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Exercise, GLUT4, and skeletal muscle glucose uptake

23 May 2018

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Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

23 May 2018

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Impaired autophagy, defective T cell homeostasis, and a wasting syndrome in mice with a T cell-specific deletion of Vps34.

23 May 2018

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Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation

23 May 2018

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Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

23 May 2018

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Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic

23 May 2018

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A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples

23 May 2018

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Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis.

23 May 2018

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Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

23 May 2018

1 reference

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Illuminating the functional and structural repertoire of human TBC/RABGAPs.

23 May 2018

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The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

23 May 2018

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Human fatty liver disease: old questions and new insights

23 May 2018

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Autophagy-deficient mice develop multiple liver tumors

23 May 2018

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Liver autophagy contributes to the maintenance of blood glucose and amino acid levels

23 May 2018

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Principles and current strategies for targeting autophagy for cancer treatment

23 May 2018

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The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation

23 May 2018

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Pik3c3 deletion in pyramidal neurons results in loss of synapses, extensive gliosis and progressive neurodegeneration

23 May 2018

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Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

23 May 2018

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Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

23 May 2018

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Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

The emerging mechanisms of isoform-specific PI3K signalling

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Autophagy regulates adipose mass and differentiation in mice

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Regulation mechanisms and signaling pathways of autophagy

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2).

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Autophagy regulates lipid metabolism

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Cell cycle-regulated expression of the muscle determination factor Myf5 in proliferating myoblasts.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Class III phosphoinositide 3-kinase/VPS34 and dynamin are critical for apical endocytic recycling.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Efficacy of metformin in type II diabetes: results of a double-blind, placebo-controlled, dose-response trial.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5703854

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-017-01969-4

Liver cell polyploidization: a pivotal role for binuclear hepatocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-017-01969-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41467-017-01969-4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29180704%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

29180704

1 reference