(Q47155204)

9 January 2018

title

A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells (English)

1 reference

9 January 2018

5

Jeffrey Schlom

1 reference

9 January 2018

James L. Gulley

4

object named as

James L Gulley

1 reference

9 January 2018

author name string

Justin M David

1

1 reference

9 January 2018

Charli Dominguez

2

1 reference

9 January 2018

Kristen K McCampbell

3

1 reference

9 January 2018

Claudia Palena

6

1 reference

9 January 2018

publication date

13 July 2017

1 reference

9 January 2018

published in

OncoImmunology

1 reference

9 January 2018

volume

6

1 reference

9 January 2018

issue

10

1 reference

9 January 2018

page(s)

e1349589

1 reference

9 January 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5665067/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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23 May 2018

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23 May 2018

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23 May 2018

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23 May 2018

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23 May 2018

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MicroRNA-138 suppresses epithelial-mesenchymal transition in squamous cell carcinoma cell lines

23 May 2018

1 reference

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An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

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23 May 2018

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The basics of epithelial-mesenchymal transition

23 May 2018

1 reference

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Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells

23 May 2018

1 reference

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A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274).

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

B7-H1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of T cell anergy.

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

PD-L1 expression is associated with epithelial-to-mesenchymal transition in adenocarcinoma of the lung

23 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

CCL2 is critical for immunosuppression to promote cancer metastasis

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5665067

TGF-beta treatment modulates PD-L1 and CD40 expression in proximal renal tubular epithelial cells and enhances CD8 cytotoxic T-cell responses

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29123964

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase 1 trial of M7824 (MSB0011359C), a bifunctional fusion protein targeting PD-L1 and TGF-β, in advanced solid tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29123964

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1080/2162402X.2017.1349589

1 reference

9 January 2018

PMC publication ID

5665067

1 reference

9 January 2018

PubMed publication ID

29123964

1 reference

9 January 2018