(Q47177885)

9 July 2018

title

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (English)

1 reference

9 July 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

1 reference

corrigendum / erratum

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Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

0 references

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

0 references

author

Anubha Mahajan

16

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9 July 2018

Mark Caulfield

66

1 reference

9 July 2018

Paul W. Franks

118

1 reference

9 July 2018

Niels Grarup

132

1 reference

9 July 2018

Torben Hansen

140

1 reference

9 July 2018

Nancy L Heard-Costa

147

1 reference

9 July 2018

Jaakko Kaprio

175

1 reference

9 July 2018

Lambertus Kiemeney

181

1 reference

9 July 2018

Helena Kuivaniemi

189

1 reference

9 July 2018

Ruifang Li-Gao

205

1 reference

9 July 2018

Lili Milani

230

1 reference

9 July 2018

Oluf Borbye Pedersen

265

1 reference

9 July 2018

Tinca Polderman

279

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9 July 2018

Matthias B Schulze

303

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9 July 2018

Albert V. Smith

311

1 reference

9 July 2018

Rudolf Uher

341

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9 July 2018

Giovanni Veronesi

354

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9 July 2018

Henrik Vestergaard

355

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9 July 2018

Daniel R. Witte

375

1 reference

9 July 2018

Wei Zhao

387

1 reference

9 July 2018

Krina Zondervan

390

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9 July 2018

Fernando Rivadeneira

393

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9 July 2018

Panos Deloukas

395

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9 July 2018

Tim Frayling

406

396

Timothy M Frayling

1 reference

9 July 2018

Gerard Pasterkamp

262

Gerard Pasterkamp

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9 July 2018

Ilaria Gandin

123

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Angela L Mazul

Angela L Mazul

225

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Massimiliano Cocca

Massimiliano Cocca

73

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Tune H Pers

Tune H Pers

272

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Betina H Thuesen

Betina H Thuesen

333

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Marit E. Jørgensen

Marit E Jørgensen

167

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Martina Müller-Nurasyid

Martina Müller-Nurasyid

242

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Honghuang Lin

Honghuang Lin

206

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Mika Kähönen

Mika Kähönen

172

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Grant W. Montgomery

Grant W Montgomery

236

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Oscar H Franco

Oscar H Franco

116

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Ian Deary

Ian J Deary

87

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Dale R Nyholt

Dale R Nyholt

252

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Tuğçe Karaderi

Tugce Karaderi

13

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Uwe Völker

Uwe Völker

Valgerdur Steinthorsdottir

358

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Valgerdur Steinthorsdottir

317

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Francis Collins

74

Francis S Collins

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Unnur Þorsteinsdóttir

332

Unnur Thorsteinsdottir

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233

Karen L Mohlke

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391

Jerome I Rotter

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Rebecca S Fine

6

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Jennifer Wessel

371

Jennifer Wessel

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89

Ellen W Demerath

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8

Tõnu Esko

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269

Markus Perola

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297

Veikko Salomaa

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338

Jaakko Tuomilehto

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Carol A Wang

364

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Christopher P Nelson

Christopher P Nelson

246

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Trevor A Mori

Trevor A Mori

239

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Marianne Benn

Marianne Benn

43

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Claudia Langenberg

Claudia Langenberg

198

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Paul Elliott

Paul Elliott

104

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Andrew J Lotery

Andrew J Lotery

218

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Terho Lehtimäki

201

Terho Lehtimäki

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Roberta McKean-Cowdin

227

Roberta McKean-Cowdin

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128

Penny Gordon-Larsen

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Eirini Marouli

17

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Ching-Ti Liu

Ching-Ti Liu

213

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Alex W. Hewitt

Alex W Hewitt

152

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John D. Rioux

John D Rioux

288

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Allan Linneberg

Allan Linneberg

212

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Andrew Tym Hattersley

Andrew T Hattersley

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Lynne E Wagenknecht

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Lynne E Wagenknecht

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46

Matthias Blüher

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Tamara B Harris

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Lars Wallentin

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Stavroula Kanoni

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Stefan Johansson

Stefan Johansson

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Mark McCarthy

Mark I McCarthy

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Heiner Boeing

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Heiner Boeing

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Nilesh J Samani

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Douglas F Easton

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Igor Rudan

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Artitaya Lophatananon

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Artitaya Lophatananon

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Michael Stumvoll

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Anke Tönjes

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Torben Jørgensen

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Pål R Njølstad

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Nicholas J Wareham

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Gonçalo Abecasis

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Evangelos Evangelou

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Michael Boehnke

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Anne U Jackson

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Ruth J F Loos

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Erwin P Bottinger

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Erik Ingelsson

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Gudmar Thorleifsson

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Sandosh Padmanabhan

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Danish Saleheen

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Danish Saleheen

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Satu Männistö

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Eric Boerwinkle

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Vilmundur Gudnason

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Naveed Sattar

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Stella Trompet

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Markku Laakso

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Sekar Kathiresan

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Anette P Gjesing

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Sven Bergmann

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Børge G. Nordestgaard

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Antonietta Robino

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Heather M Stringham

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Lars Lind

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Stefan Gustafsson

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Frida Renström

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Dragana Vuckovic

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Yongmei Liu

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Alison M Dunning

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Charles Kooperberg

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Kári Stefánsson

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Kari Stefansson

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Hanieh Yaghootkar

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Hanieh Yaghootkar

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Konstantin Strauch

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Annette Peters

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Cecilia Lindgren

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Cecilia M Lindgren

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Fredrik Karpe

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Fredrik Karpe

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Anu Loukola

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Anu Loukola

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Leo-Pekka Lyytikäinen

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Leo-Pekka Lyytikäinen

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Johanna Kuusisto

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Andrew C Heath

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Zoltán Kutalik

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René S. Kahn

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René S Kahn

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Cora E Lewis

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Cora E Lewis

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Ivan Brandslund

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Ivan Brandslund

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Sharon L R Kardia

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Sharon L R Kardia

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Myriam Fornage

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Myriam Fornage

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Ingrid B Borecki

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Ingrid B Borecki

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Lisa Bastarache

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Lisa Bastarache

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Paul Ridker

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Paul M Ridker

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Kari E North

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Kari E North

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Olli Raitakari

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Olli T Raitakari

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Mary Feitosa

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Mary F Feitosa

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Daniel I Chasman

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Daniel I Chasman

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Mariaelisa Graff

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Mariaelisa Graff

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David J Carey

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David J Carey

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Kjell Nikus

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Kjell Nikus

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Patricia B Munroe

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Patricia B Munroe

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Yen-Chu Chen

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Yii-Der I Chen

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Eleuterio Ferrannini

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Ele Ferrannini

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Digna R. Velez Edwards

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Digna R Velez Edwards

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Todd L. Edwards

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Todd L Edwards

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Heather M. Highland

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Heather M Highland

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Mauno Vanhala

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Mauno Vanhala

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Jaspal Kooner

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Jaspal S Kooner

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Kent D Taylor

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Kent D Taylor

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Hakon Hakonarson

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Hakon Hakonarson

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Donald W Bowden

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Donald W Bowden

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Nicholette D Palmer

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Nicholette D Palmer

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Lawrence F Bielak

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Lawrence F Bielak

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Patricia A Peyser

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Patricia A Peyser

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Dawn Waterworth

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Dawn M Waterworth

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Dennis O Mook-Kanamori

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Dennis O Mook-Kanamori

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Alexander Teumer

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Alexander Teumer

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J Wouter Jukema

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J Wouter Jukema

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James G. Wilson

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James G Wilson

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Gerome Breen

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Gerome Breen

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John Danesh

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John Danesh

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Laura M Yerges-Armstrong

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Laura M Yerges-Armstrong

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Alisa Manning

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Alisa K Manning

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Tim D. Spector

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Timothy D Spector

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Steven A Lubitz

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Steven A Lubitz

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Patrick T Ellinor

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Patrick T Ellinor

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Joel N Hirschhorn

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Joel N Hirschhorn

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Peter Kovacs

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Peter Kovacs

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Maria Karaleftheri

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Maria Karaleftheri

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Jean-Claude Tardif

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Jean-Claude Tardif

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Andre Franke

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Andre Franke

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Robert A Scott

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Robert A Scott

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Andrew R Wood

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Andrew R Wood

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David-Alexandre Trégouët

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David Lamparter

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Folkert Asselbergs

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Folkert W Asselbergs

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Adam S. Butterworth

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Adam S Butterworth

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Jessica D. Faul

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Jessica D Faul

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Oddgeir L Holmen

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Oddgeir L Holmen

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M. Arfan Ikram

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M Arfan Ikram

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Timo A. Lakka

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Timo A Lakka

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Colin Palmer

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Colin N A Palmer

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Gina M Peloso

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Gina M Peloso

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Katherine S Ruth

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Katherine S Ruth

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Kerrin S. Small

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Kerrin S Small

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Elizabeth K Speliotes

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Elizabeth K Speliotes

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John M Starr

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Jonathan P Tyrer

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Jonathan P Tyrer

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Sita H Vermeulen

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Helen R Warren

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Helen R Warren

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Cristen J. Willer

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Cristen J Willer

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Jennifer E Huffman

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Jennifer E Huffman

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G Kees Hovingh

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Christian T Have

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Struan F A Grant

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Ozren Polasek

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Inês Barroso

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Sameer E Alharthi

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Josh C Denny

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Jean Ferrieres

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Sarah E Medland

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Craig E Pennell

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Ailith Pirie

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Valérie Turcot

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Poorva Mudgal

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Xiuqing Guo

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Katja K Aben

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Paul L Auer

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Lia E Bang

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Carsten A Böger

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Michiel L Bots

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Murray H. Brilliant

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Murray H Brilliant

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Linda Broer

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Amber A Burt

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Rajiv Chowdhury

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Cramer Christensen

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Cramer Christensen

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Audrey Y Chu

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Janie Corley

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Jordi Corominas Galbany

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Joe Dennis

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Joe G Dennis

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Emanuele Di Angelantonio

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Emanuele Di Angelantonio

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Fotios Drenos

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Fotios Drenos

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Aliki-Eleni Farmaki

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Aliki-Eleni Farmaki

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Jussi Hernesniemi

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Joanna M M Howson

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Jan-Håkan Jansson

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Gail P Jarvik

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Yucheng Jia

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Pia R Kamstrup

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Frank Kee

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Jaana Lindström

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Gaëlle Marenne

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Karina Meidtner

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Mike A Nalls

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Matt Neville

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Sune G. Nielsen

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Loes M Olde Loohuis

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Loes M Olde Loohuis

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Roel A Ophoff

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Alison Pattie

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Asif Rasheed

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Olov Rolandsson

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Marcelo P Segura-Lepe

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Svati H Shah

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Xueling Sim

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Xueling Sim

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Anette Varbo

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Feijie Wang

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Guillaume Lettre

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Nele Friedrich

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Nele Friedrich

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Jonathan P Bradfield

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MAGIC investigators

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MAGIC Investigators

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ReproGen Consortium

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ReproGen Consortium

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Hannu Puolijoki

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Hannu Puolijoki

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EPIC InterAct Consortium

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EPIC InterAct Consortium

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Caroline Hayward

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Caroline Hayward

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Wayne H-H Sheu

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Audrey E Hendricks

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Adelheid Lempradl

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Tamuno Alfred

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Sailaja Vedantam

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Matthew A. Allison

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Matthew Allison

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Beverley Balkau

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Marco Brumat

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Stefania Cappellani

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Eulalia Catamo

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Eulalia Catamo

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David R Crosslin

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David S Crosslin

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Angela D'Eustacchio

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Renée Mutsert

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Martin den Heijer

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Martin Heijer

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Sascha Fauser

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Sascha Fauser

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Hans-Jörgen Grabe

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Jeff Haessler

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Anke R Hammerschlag

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Tellervo Korhonen

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Kari Kuulasmaa

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Kari Kuulasmaa

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Nanette R Lee

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Nanette R Lee

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Keng-Hung Lin

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Keng-Hung Lin

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Vanisha Mistry

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Vanisha Mistry

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Marie Moitry

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Marie Moitry

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Carmel Moore

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Carmel Moore

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Michelle L O'Donoghue

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Michelle L O'Donoghue

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Rainer Rauramaa

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Yadav Sapkota

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Hayato Tada

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Hayato Tada

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Gerard Tromp

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Gerard Tromp

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Erin Ware

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Erin B Ware

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John Andrew Pospisilik

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John A Pospisilik

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CHD Exome+ Consortium

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CHD Exome+ Consortium

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ExomeBP Consortium

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ExomeBP Consortium

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INTERVAL Study

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INTERVAL Study

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T2D-Genes Consortium

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T2D-Genes Consortium

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Understanding Society Scientific Group

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Understanding Society Scientific Group

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Gorm Boje Jensen

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Gorm B Jensen

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James A Perry

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James A Perry

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Leslie A. Lange

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Leslie A Lange

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Kathleen Stirrups

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Kathleen E Stirrups

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George Dedoussis

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George Dedoussis

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Vilmantas Giedraitis

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Vilmantas Giedraitis

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Sadaf Farooqi

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I Sadaf Farooqi

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Andrew P Morris

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Andrew P Morris

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Ian Ford

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Ian Ford

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Harvey D. White

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Harvey D White

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Pamela J Schreiner

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Pamela J Schreiner

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Yingchang Lu

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Maggie C Y Ng

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Alex P Reiner

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Sara M Willems

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Peter T Campbell

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John C Chambers

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James P Cook

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Amanda J Cox

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Gabriel Cuellar-Partida

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Gail Davies

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Mark C H Groot

85

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Anneke I Hollander

91

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Hester M Ruijter

92

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9 July 2018

Mengmeng Du

97

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9 July 2018

David Ellinghaus

102

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9 July 2018

Shuang Feng

110

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9 July 2018

Jose C Florez

113

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9 July 2018

Tessel E Galesloot

121

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9 July 2018

Wei Gan

122

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9 July 2018

Paolo Gasparini

124

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9 July 2018

Jane Gibson

125

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9 July 2018

Mathias Gorski

129

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Helen L Griffiths

133

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9 July 2018

Megan L Grove

134

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9 July 2018

Liang He

146

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9 July 2018

Yao Hu

156

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9 July 2018

Paul L Huang

157

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9 July 2018

Eric Kim

182

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9 July 2018

Pirjo Komulainen

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Ethan M Lange

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9 July 2018

Eric B Larson

199

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9 July 2018

Huaixing Li

203

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9 July 2018

Jin Li

204

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9 July 2018

Li-An Lin

208

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9 July 2018

Xu Lin

209

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9 July 2018

Ken S Lo

216

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Jian'an Luan

220

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9 July 2018

Paul Mitchell

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Leena Moilanen

234

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Narisu Narisu

245

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Katharine R Owen

257

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Chris J Packard

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John R B Perry

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Thomas N Person

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Eva R B Petersen

275

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Dermot F Reilly

284

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Manuel A Rivas

289

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9 July 2018

David J Roberts

290

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Neil R Robertson

291

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Robert E Schoen

301

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9 July 2018

Liang Sun

322

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9 July 2018

Amy J Swift

324

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9 July 2018

Matti Uusitupa

343

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9 July 2018

Sander W Laan

344

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9 July 2018

Cornelia M Duijn

345

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9 July 2018

Nienke Leeuwen

346

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Jessica van Setten

347

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Rohit Varma

351

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Veronique Vitart

356

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9 July 2018

Thomas F Vogt

357

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9 July 2018

Mark Walker

361

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9 July 2018

Shuai Wang

365

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9 July 2018

Yiqin Wang

366

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9 July 2018

Ying Wu

377

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9 July 2018

Jie Yao

379

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9 July 2018

Pang Yao

380

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9 July 2018

Robin Young

382

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9 July 2018

Xiaowei Zhan

384

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9 July 2018

Weihua Zhang

385

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9 July 2018

Jing Hua Zhao

386

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9 July 2018

Andrew D Morris

240

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9 July 2018

language of work or name

English

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publication date

22 December 2017

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9 July 2018

published in

Nature Genetics

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9 July 2018

volume

50

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9 July 2018

page(s)

26-41

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9 July 2018

issue

1

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9 July 2018

https://scigraph.springernature.com/pub.10.1038/s41588-017-0011-x

exact match

0 references

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Rare and low-frequency coding variants alter human adult height

10 July 2018

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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

10 July 2018

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Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

10 July 2018

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Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

10 July 2018

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Analysis of protein-coding genetic variation in 60,706 humans

10 July 2018

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Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist

10 July 2018

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The genetic architecture of type 2 diabetes

10 July 2018

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Role of Exchange Protein Directly Activated by Cyclic AMP Isoform 1 in Energy Homeostasis: Regulation of Leptin Expression and Secretion in White Adipose Tissue

10 July 2018

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Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

10 July 2018

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Hypothalamic AMPK: a canonical regulator of whole-body energy balance

10 July 2018

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RVTESTS: an efficient and comprehensive tool for rare variant association analysis using sequence data

10 July 2018

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Hypomorphism of Fto and Rpgrip1l causes obesity in mice

10 July 2018

1 reference

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Reappraisal of GIP Pharmacology for Metabolic Diseases

10 July 2018

1 reference

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ZFHX3 knockdown increases arrhythmogenesis and dysregulates calcium homeostasis in HL-1 atrial myocytes

10 July 2018

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10 July 2018

Management of obesity

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The effect of phenotypic outliers and non-normality on rare-variant association testing

10 July 2018

1 reference

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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

10 July 2018

1 reference

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Skeletal muscle AMP-activated protein kinase γ1(H151R) overexpression enhances whole body energy homeostasis and insulin sensitivity

10 July 2018

1 reference

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FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

10 July 2018

1 reference

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Rare coding variants and X-linked loci associated with age at menarche

10 July 2018

1 reference

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The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis

10 July 2018

1 reference

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Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeutics

10 July 2018

1 reference

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Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

10 July 2018

1 reference

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A neural basis for melanocortin-4 receptor-regulated appetite

10 July 2018

1 reference

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Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES)

10 July 2018

1 reference

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The hunger genes: pathways to obesity

10 July 2018

1 reference

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Genetic studies of body mass index yield new insights for obesity biology

10 July 2018

1 reference

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Biological interpretation of genome-wide association studies using predicted gene functions

10 July 2018

1 reference

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EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data

10 July 2018

1 reference

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Deletion of atbf1/zfhx3 in mouse prostate causes neoplastic lesions, likely by attenuation of membrane and secretory proteins and multiple signaling pathways

10 July 2018

1 reference

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RAREMETAL: fast and powerful meta-analysis for rare variants

10 July 2018

1 reference

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Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

10 July 2018

1 reference

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Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice

10 July 2018

1 reference

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Quality control and conduct of genome-wide association meta-analyses

10 July 2018

1 reference

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Obesity-associated variants within FTO form long-range functional connections with IRX3

10 July 2018

1 reference

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Update on obesity pharmacotherapy

10 July 2018

1 reference

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Interaction of acetylcholinesterase with neurexin-1β regulates glutamatergic synaptic stability in hippocampal neurons

10 July 2018

1 reference

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AMPK: regulating energy balance at the cellular and whole body levels.

10 July 2018

1 reference

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Differential regulation of lipid metabolism genes in the brain of acetylcholinesterase knockout mice

10 July 2018

1 reference

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A polygenic burden of rare disruptive mutations in schizophrenia

10 July 2018

1 reference

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Meta-analysis of gene-level tests for rare variant association

10 July 2018

1 reference

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Cyclic AMP sensor EPAC proteins and energy homeostasis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Beyond GWASs: illuminating the dark road from association to function

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Formation of chimeric genes by copy-number variation as a mutational mechanism in schizophrenia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Enhanced leptin sensitivity, reduced adiposity, and improved glucose homeostasis in mice lacking exchange protein directly activated by cyclic AMP isoform 1

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

zCall: a rare variant caller for array-based genotyping: genetics and population analysis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Long-term safety and tolerability of donepezil 23 mg in patients with moderate to severe Alzheimer's disease

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Exome sequencing and the genetic basis of complex traits

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

AMPK: a nutrient and energy sensor that maintains energy homeostasis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Rare-variant association testing for sequencing data with the sequence kernel association test

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Safety and tolerability of donepezil 23 mg in moderate to severe Alzheimer's disease

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Genomic inflation factors under polygenic inheritance

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Effectiveness and tolerability of high-dose (23 mg/d) versus standard-dose (10 mg/d) donepezil in moderate to severe Alzheimer's disease: A 24-week, randomized, double-blind study

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

METAL: fast and efficient meta-analysis of genomewide association scans

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Pooled association tests for rare variants in exon-resequencing studies

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Epac, not PKA catalytic subunit, is required for 3T3-L1 preadipocyte differentiation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Proteomic characterization of the dynamic KSR-2 interactome, a signaling scaffold complex in MAPK pathway

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Evidence for beneficial effects of compromised gastric inhibitory polypeptide action in obesity-related diabetes and possible therapeutic implications.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Vaccination against GIP for the treatment of obesity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

The Creb1 coactivator Crtc1 is required for energy balance and fertility

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Prevalence of melanocortin-4 receptor deficiency in Europeans and their age-dependent penetrance in multigenerational pedigrees.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Hip1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126).

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Bacterial expression, characterization, and disulfide bond determination of soluble human NTPDase6 (CD39L2) nucleotidase: implications for structure and function

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Cidea-deficient mice have lean phenotype and are resistant to obesity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Distinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant mice

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Central nervous system control of food intake

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

A frameshift mutation in human MC4R is associated with a dominant form of obesity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

A frameshift mutation in MC4R associated with dominantly inherited human obesity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Mutation at codon 322 in the human acetylcholinesterase (ACHE) gene accounts for YT blood group polymorphism

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

The Zfhx3-Mediated Axis Regulates Sleep and Interval Timing in Mice.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Comparative gene array analysis of progenitor cells from human paired deep neck and subcutaneous adipose tissue.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Exchange protein activated by cAMP 1 (Epac1)-deficient mice develop β-cell dysfunction and metabolic syndrome.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5945951

Non-synonymous polymorphisms in melanocortin-4 receptor protect against obesity: the two facets of a Janus obesity gene

14 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41588-017-0011-X

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41588-017-0011-X

Melanocortin-4 Receptor Gene Mutations in a Dutch Cohort of Obese Children

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41588-017-0011-X

Genetic ablation of acetylcholinesterase alters muscle function in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41588-017-0011-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Profound obesity secondary to hyperphagia in mice lacking kinase suppressor of ras 2

1 reference

https://api.crossref.org/works/10.1038%2FS41588-017-0011-X

inferred from DOI database lookup

7 January 2021

based on heuristic

High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FS41588-017-0011-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41588-017-0011-X

1 reference

9 July 2018

1 reference

9 July 2018

PubMed ID

29273807

1 reference

9 July 2018