(Q47229547)

8 July 2018

meta-analysis

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title

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects (English)

1 reference

8 July 2018

genome-wide association study

main subject

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author

Carolina Medina-Gomez

1

1 reference

8 July 2018

Leon E Jessen

23

1 reference

8 July 2018

Bo L Chawes

27

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8 July 2018

Cindy G Boer

39

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8 July 2018

Ruifang Li-Gao

46

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8 July 2018

Hans Bisgaard

62

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8 July 2018

Unnur Styrkarsdottir

63

1 reference

8 July 2018

Christian J Carlsson

Christian J Carlsson

36

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Katerina Trajanoska

Katerina Trajanoska

3

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Ivana Nedeljkovic

Ivana Nedeljkovic

12

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Benjamin H Mullin

Benjamin H Mullin

20

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John P Kemp

John P Kemp

2

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Scott G Wilson

Scott G Wilson

60

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John P. Walsh

John P Walsh

43

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Mohsen Ghanbari

Mohsen Ghanbari

79

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Martin den Heijer

Martin den Heijer

52

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David M. Evans

David M Evans

88

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Claes Ohlsson

Claes Ohlsson

75

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Carol A Wang

Carol Wang

26

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Claudia Langenberg

Claudia Langenberg

45

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Ching-Ti Liu

Ching-Ti Liu

16

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Tamara B. Harris

48

Tamara B Harris

1 reference

PMCID

5777980

8 July 2018

Cheryl L Ackert-Bicknell

Cheryl L Ackert-Bicknell

86

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Peter I Croucher

Peter I Croucher

83

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Evangelos Evangelou

84

Evangelos Evangelou

1 reference

PMCID

5777980

8 July 2018

Cornelia M. van Duijn

70

Cornelia M van Duijn

1 reference

8 July 2018

31

David Karasik

1 reference

8 July 2018

69

Mattias Lorentzon

1 reference

8 July 2018

40

Klaus Bønnelykke

1 reference

8 July 2018

37

Yongmei Liu

1 reference

8 July 2018

89

Fernando Rivadeneira

1 reference

8 July 2018

72

Kari Stefansson

1 reference

8 July 2018

Bruce M. Psaty

73

Bruce M Psaty

1 reference

8 July 2018

Andre J van Wijnen

77

Andre J van Wijnen

1 reference

8 July 2018

Vincent W Jaddoe

64

Vincent W Jaddoe

1 reference

8 July 2018

Dennis O Mook-Kanamori

7

Dennis O Mook-Kanamori

1 reference

8 July 2018

James F. Wilson

71

James F Wilson

1 reference

8 July 2018

Alessandra Chesi

5

Alessandra Chesi

1 reference

8 July 2018

Tarunveer S Ahluwalia

6

Tarunveer S Ahluwalia

1 reference

8 July 2018

Fernando P Hartwig

9

Fernando P Hartwig

1 reference

8 July 2018

J Brent Richards

25

J Brent Richards

1 reference

8 July 2018

Nathalie van der Velde

32

Nathalie Van der Velde

1 reference

8 July 2018

Babette S Zemel

34

Babette S Zemel

1 reference

8 July 2018

Tim D. Spector

55

Timothy D Spector

1 reference

8 July 2018

M. Carola Zillikens

44

M Carola Zillikens

1 reference

8 July 2018

Rebecca D. Jackson

50

Rebecca D Jackson

1 reference

8 July 2018

Frances M. Williams

47

Frances M K Williams

1 reference

8 July 2018

Daniel S Evans

10

Daniel S Evans

1 reference

8 July 2018

M. Arfan Ikram

33

M Arfan Ikram

1 reference

8 July 2018

Stuart H Ralston

41

Stuart H Ralston

1 reference

8 July 2018

Timo A. Lakka

66

Timo A Lakka

1 reference

8 July 2018

Robert A Scott

67

Robert Scott

1 reference

8 July 2018

Douglas P. Kiel

74

Douglas P Kiel

1 reference

8 July 2018

André Uitterlinden

85

Andre G Uitterlinden

1 reference

8 July 2018

Nick J Wareham

30

Nick Wareham

1 reference

8 July 2018

Denise H M Heppe

24

Denise H M Heppe

1 reference

8 July 2018

Hou-Feng Zheng

13

Hou-Feng Zheng

1 reference

8 July 2018

Samuel K Handelman

21

Samuel K Handelman

1 reference

8 July 2018

Mustafa Atalay

15

Mustafa Atalay

1 reference

8 July 2018

Struan F.A. Grant

68

Struan F A Grant

1 reference

8 July 2018

Maria Nethander

17

Maria Nethander

1 reference

8 July 2018

Eric Orwoll

65

Eric Orwoll

1 reference

8 July 2018

Najaf Amin

29

Najaf Amin

1 reference

8 July 2018

Linda Broer

18

Linda Broer

1 reference

8 July 2018

Yanhua Zhou

35

Yanhua Zhou

1 reference

8 July 2018

Kristina Åkesson

49

Kristina Akesson

1 reference

8 July 2018

Renée de Mutsert

61

Renée de Mutsert

1 reference

8 July 2018

Vincenzo Forgetta

78

Vincenzo Forgetta

1 reference

8 July 2018

Craig E. Pennell

56

Craig Pennell

1 reference

8 July 2018

Janine F Felix

58

Janine F Felix

1 reference

8 July 2018

Raimo Joro

11

Raimo Joro

1 reference

8 July 2018

Bernardo L. Horta

57

Bernardo L Horta

1 reference

8 July 2018

author name string

Jian'an Luan

4

1 reference

8 July 2018

Annelies Ham

8

1 reference

8 July 2018

Kun Zhu

14

1 reference

8 July 2018

Gudmar Porleifsson

19

1 reference

8 July 2018

Mike A Nalls

22

1 reference

8 July 2018

Katharina E Schraut

28

1 reference

8 July 2018

Fiona E McGuigan

38

1 reference

8 July 2018

John A Robbins

42

1 reference

8 July 2018

Gunnar Sigurdsson

51

1 reference

8 July 2018

Bram C J van der Eerden

53

1 reference

8 July 2018

Jeroen van de Peppel

54

1 reference

8 July 2018

Jing Hua Zhao

59

1 reference

8 July 2018

Evangelia Ntzani

76

1 reference

8 July 2018

John G Logan

80

1 reference

8 July 2018

Graham R Williams

81

1 reference

8 July 2018

J H Duncan Bassett

82

1 reference

8 July 2018

Jonathan H Tobias

87

1 reference

8 July 2018

language of work or name

English

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publication date

1 January 2018

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8 July 2018

American Journal of Human Genetics

published in

1 reference

8 July 2018

volume

102

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8 July 2018

issue

1

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8 July 2018

page(s)

88-102

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8 July 2018

describes a project that uses

genome-wide association study

1 reference

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

cites work

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Identification of Three Early Phases of Cell-Fate Determination during Osteogenic and Adipogenic Differentiation by Transcription Factor Dynamics

10 July 2018

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10 July 2018

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10 July 2018

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10 July 2018

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Serum miRNA Signatures Are Indicative of Skeletal Fractures in Postmenopausal Women With and Without Type 2 Diabetes and Influence Osteogenic and Adipogenic Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells In Vitro.

10 July 2018

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Association of 3q13.32 variants with hip trochanter and intertrochanter bone mineral density identified by a genome-wide association study

10 July 2018

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Vitamin D3 transactivates the zinc and manganese transporter SLC30A10 via the Vitamin D receptor

10 July 2018

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MMP-9 facilitates selective proteolysis of the histone H3 tail at genes necessary for proficient osteoclastogenesis

10 July 2018

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Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures

10 July 2018

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10 July 2018

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Deletion of the intestinal plasma membrane calcium pump, isoform 1, Atp2b1, in mice is associated with decreased bone mineral density and impaired responsiveness to 1, 25-dihydroxyvitamin D3.

10 July 2018

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Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

10 July 2018

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Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

10 July 2018

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Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton

10 July 2018

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10 July 2018

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Skeletal changes through the lifespan--from growth to senescence

10 July 2018

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A look behind the scenes: the risk and pathogenesis of primary osteoporosis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

10 July 2018

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Biological interpretation of genome-wide association studies using predicted gene functions

10 July 2018

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Anoctamin-6 controls bone mineralization by activating the calcium transporter NCX1

10 July 2018

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Smad9 is a new type of transcriptional regulator in bone morphogenetic protein signaling

10 July 2018

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EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data

10 July 2018

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Dual-specificity phosphatase 5 attenuates autoimmune arthritis in mice via reciprocal regulation of the Th17/Treg cell balance and inhibition of osteoclastogenesis.

10 July 2018

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Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

10 July 2018

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Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment

10 July 2018

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Quality control and conduct of genome-wide association meta-analyses

10 July 2018

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Runx1-mediated regulation of osteoclast differentiation and function

10 July 2018

1 reference

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Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

10 July 2018

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Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

10 July 2018

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10 July 2018

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PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways

10 July 2018

1 reference

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Mendelian randomization analysis with multiple genetic variants using summarized data

10 July 2018

1 reference

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Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

10 July 2018

1 reference

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Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/β-catenin signaling

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Association between DHEAS and bone loss in postmenopausal women: a 15-year longitudinal population-based study

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Involvement of PRIP, phospholipase C-related, but catalytically inactive protein, in bone formation

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Genetic variants in the SOX6 gene are associated with bone mineral density in both Caucasian and Chinese populations.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

MicroSNiPer: a web tool for prediction of SNP effects on putative microRNA targets

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Effects of the bisphosphonate risedronate on osteopenia in OASIS-deficient mice

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Noncanonical frizzled signaling regulates cell polarity of growth plate chondrocytes

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Regulation of bone mass by Wnt signaling

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

CD44 is a determinant of inflammatory bone loss

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Ets2 transcription factor inhibits mineralization and affects target gene expression during osteoblast maturation.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Osteoclastogenic capacity of peripheral blood mononuclear cells is not different between women with and without osteoporosis.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Two Rare Mutations in the COL1A2 Gene Associate With Low Bone Mineral Density and Fractures in Iceland

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Degenerative changes at the lumbar spine--implications for bone mineral density measurement in elderly women

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integrity, and endochondral ossification.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Expression of RANKL and OPG correlates with age-related bone loss in male C57BL/6 mice

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Genetic Variations in MicroRNA-Binding Sites Affect MicroRNA-Mediated Regulation of Several Genes Associated With Cardio-metabolic Phenotypes

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5777980

Mutation of macrophage colony stimulating factor (Csf1) causes osteopetrosis in the tl rat

1 December 2018

1 reference

12 December 2020

Predictive Value of BMD for Hip and Other Fractures

1 reference

12 December 2020

MafB negatively regulates RANKL-mediated osteoclast differentiation

1 reference

12 December 2020

Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis

1 reference

12 December 2020

10.1016/J.AJHG.2017.12.005

Identifiers

DOI

1 reference

8 July 2018

PMCID

5777980

1 reference

8 July 2018

PubMed ID

29304378

1 reference

8 July 2018