(Q38434317)

3 September 2017

1 reference

title

A look behind the scenes: the risk and pathogenesis of primary osteoporosis (English)

1 reference

3 September 2017

Eveline Boudin

2

0 references

Wim Van Hul

object named as

Wim Van Hul

series ordinal

3

0 references

author name string

Gretl Hendrickx

series ordinal

1

1 reference

PubMed ID

25900210

3 September 2017

language of work or name

English

0 references

publication date

21 April 2015

1 reference

Nature Reviews Rheumatology

3 September 2017

1 reference

3 September 2017

11

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3 September 2017

8

1 reference

3 September 2017

462-474

1 reference

https://scigraph.springernature.com/pub.10.1038/nrrheum.2015.48

3 September 2017

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cites work

Excess mortality following hip fracture: a systematic epidemiological review

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Osteoporosis, frailty and fracture: implications for case finding and therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

How many women have osteoporosis now?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Direct clinical and welfare costs of osteoporotic fractures in elderly men and women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Acquisition of optimal bone mass in childhood and adolescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Osteoblastogenesis regulation signals in bone remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The contribution of collagen crosslinks to bone strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Biological regulation of bone quality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Effects of bone matrix proteins on fracture and fragility in osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Bone geometry and skeletal fragility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

21 January 2018

Aging mechanisms in bone

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Premature aging in mice deficient in DNA repair and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

p53 mutant mice that display early ageing-associated phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Reactive oxygen species on bone mineral density and mechanics in Cu,Zn superoxide dismutase (Sod1) knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Unraveling the role of FoxOs in bone--insights from mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Functional interaction between beta-catenin and FOXO in oxidative stress signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Modulation of mammalian life span by the short isoform of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Dysapoptosis of osteoblasts and osteocytes increases cancellous bone formation but exaggerates cortical porosity with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The Death of Osteocytes via Apoptosis Accompanies Estrogen Withdrawal in Human Bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Increased proportion of hypermineralized osteocyte lacunae in osteoporotic and osteoarthritic human trabecular bone: implications for bone remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The role of estrogen and androgen receptors in bone health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Periosteal bone formation--a neglected determinant of bone strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The estrogen receptor-alpha in osteoclasts mediates the protective effects of estrogens on cancellous but not cortical bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Mineralization and bone resorption are regulated by the androgen receptor in male mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Androgen receptor (AR) in osteocytes is important for the maintenance of male skeletal integrity: evidence from targeted AR disruption in mouse osteocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Reversal of bone loss in mice by nongenotropic signaling of sex steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Pro-survival effects of 17β-estradiol on osteocytes are mediated by nitric oxide/cGMP via differential actions of cGMP-dependent protein kinases I and II

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Pathogenesis of bone fragility in women and men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The decline of androgen levels in elderly men and its clinical and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Bone turnover markers in peripheral blood and marrow plasma reflect trabecular bone loss but not endocortical expansion in aging mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Effects of chronic estrogen treatment on modulating age-related bone loss in female mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

For whom the bell tolls: distress signals from long-lived osteocytes and the pathogenesis of metabolic bone diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Autophagy: a new player in skeletal maintenance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Autophagy--a key player in cellular and body metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Nutrient-dependent regulation of autophagy through the target of rapamycin pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Autophagy proteins regulate the secretory component of osteoclastic bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Suppression of autophagy in osteocytes mimics skeletal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Dairy in adulthood: from foods to nutrient interactions on bone and skeletal muscle health

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Vitamin D and bone disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Vitamin D: direct effects of vitamin D metabolites on bone: lessons from genetically modified mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Antioxidants and human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Fruits and dietary phytochemicals in bone protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Fruit and vegetable intake and bone mass in Chinese adolescents, young and postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Impact of seafood and fruit consumption on bone mineral density.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Nutritional disturbance in acid-base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Oxidative stress and antioxidants in exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Mechanical signals as anabolic agents in bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Osteocyte: the unrecognized side of bone tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The role of extracellular modulators of canonical Wnt signaling in bone metabolism and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Wnt and the Wnt signaling pathway in bone development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Extraskeletal benefits and risks of calcium, vitamin D and anti-osteoporosis medications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Effects of nutrition and alcohol consumption on bone loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

A role for ethanol-induced oxidative stress in controlling lineage commitment of mesenchymal stromal cells through inhibition of Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the extracellular signal-regulated kinase/signal transducer and activator of [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Smoking and fracture risk: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

A meta-analysis of the effects of cigarette smoking on bone mineral density

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The effects of smoking on bone metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

New genes in bone development: what's new in osteogenesis imperfecta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Genetic heterogeneity in osteogenesis imperfecta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Osteogenesis imperfecta: clinical diagnosis, nomenclature and severity assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Next-generation sequencing: a frameshift in skeletal dysplasia gene discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Nosology and classification of genetic skeletal disorders: 2010 revision.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

EMQN best practice guidelines for the laboratory diagnosis of osteogenesis imperfecta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

A brilliant breakthrough in OI type V.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Bone collagen: new clues to its mineralization mechanism from recessive osteogenesis imperfecta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Increased cell surface expression of receptors for transforming growth factor-beta on osteoblasts from patients with Osteogenesis imperfecta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Identification of a frameshift mutation in Osterix in a patient with recessive osteogenesis imperfecta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Mutations in WNT1 cause different forms of bone fragility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Whole-exome sequencing reveals a heterozygous LRP5 mutation in a 6-year-old boy with vertebral compression fractures and low trabecular bone density.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Mutations in LRP5 cause primary osteoporosis without features of OI by reducing Wnt signaling activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Missense mutations in LRP5 are not a common cause of idiopathic osteoporosis in adult men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

PLS3 mutations in X-linked osteoporosis with fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Various types of LRP5 mutations in four patients with osteoporosis-pseudoglioma syndrome: identification of a 7.2-kb microdeletion using oligonucleotide tiling microarray.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The genetics of low-density lipoprotein receptor-related protein 5 in bone: a story of extremes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Mutations in PLOD2 cause autosomal-recessive connective tissue disorders within the Bruck syndrome--osteogenesis imperfecta phenotypic spectrum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Mutations in FKBP10 cause both Bruck syndrome and isolated osteogenesis imperfecta in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

An eQTL mapping approach reveals that rare variants in the SEMA5A regulatory network impact autism risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: results from the National Osteoporosis Risk Assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Clinical review 2: Genetic determinants of bone density and fracture risk--state of the art and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Multiple genetic loci for bone mineral density and fractures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

European bone mineral density loci are also associated with BMD in East-Asian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Homozygous deletion of the UGT2B17 gene is not associated with osteoporosis risk in elderly Caucasian women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Genome-wide copy number variation association study suggested VPS13B gene for osteoporosis in Caucasians

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Epigenetic influences in the developmental origins of osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Epigenetic mechanisms in bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Do epigenetic marks govern bone mass and homeostasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Sirt1 is a regulator of bone mass and a repressor of Sost encoding for sclerostin, a bone formation inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

MicroRNA functions in osteogenesis and dysfunctions in osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

MicroRNAs and post-transcriptional regulation of skeletal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

DNA methylation contributes to the regulation of sclerostin expression in human osteocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Role of DNA methylation in the regulation of the RANKL-OPG system in human bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Sclerosing bone dysplasias: leads toward novel osteoporosis treatments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Romosozumab in postmenopausal women with low bone mineral density.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

A randomized, double-blind phase 2 clinical trial of blosozumab, a sclerostin antibody, in postmenopausal women with low bone mineral density

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Primary osteoporosis without features of OI in children and adolescents: Clinical and genetic characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Requirements for DXA for the management of osteoporosis in Europe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Osteocyte control of bone remodeling: is sclerostin a key molecular coordinator of the balanced bone resorption-formation cycles?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Cytoplasmic superoxide causes bone fragility owing to low-turnover osteoporosis and impaired collagen cross-linking

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

The Role of Estrogen in the Control of Rat Osteocyte Apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Osteoblast Deletion of Exon 3 of the Androgen Receptor Gene Results in Trabecular Bone Loss in Adult Male Mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Dietary influences on bone mass and bone metabolism: further evidence of a positive link between fruit and vegetable consumption and bone health?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Fruit and vegetable intakes and bone mineral status: a cross sectional study in 5 age and sex cohorts.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Amount and type of protein influences bone health

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Dietary protein content and the diet's net acid load: opposing effects on bone health

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Effects of osteoclastic resorption on bone surface ion composition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Alcohol and bone: review of dose effects and mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Osteoporosis caused by mutations in PLS3: clinical and bone tissue characteristics

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Mutations in FKBP10, which result in Bruck syndrome and recessive forms of osteogenesis imperfecta, inhibit the hydroxylation of telopeptide lysines in bone collagen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

31 March 2020

Genetics of osteoporosis

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

31 March 2020

Genetics of osteoporosis

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

Biological agents in management of osteoporosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2015.48

31 March 2020

1 reference

12 December 2020

Metabolic alkalosis decreases bone calcium efflux by suppressing osteoclasts and stimulating osteoblasts

1 reference

12 December 2020

Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERalpha

1 reference

12 December 2020

The death of osteocytes via apoptosis accompanies estrogen withdrawal in human bone

1 reference

12 December 2020

OMIM.org: Online Mendelian Inheritance in Man (OMIM®), an online catalog of human genes and genetic disorders

1 reference

12 December 2020

Pre-operative pulmonary assessment for patients with hip fracture

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2015.48

1 reference

PubMed ID

25900210

Dimensions Publication ID

3 September 2017

0 references

1 reference

PubMed ID

25900210