(Q47316471)

English

Mutations at the Ser50 residue of translation factor eIF-2alpha dominantly affect developmental rate, body weight, and viability of Drosophila melanogaster.

scientific article published in January 1997

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scholarly article

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9 November 2019

Mutations at the Ser50 residue of translation factor eIF-2alpha dominantly affect developmental rate, body weight, and viability of Drosophila melanogaster (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495316%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Drosophila melanogaster

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4

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9 November 2019

Douglas R. Cavener

5

object named as

D R Cavener

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9 November 2019

author name string

S Qu

1

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9 November 2019

S E Perlaky

2

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9 November 2019

E L Organ

3

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9 November 2019

publication date

1 January 1997

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9 November 2019

Gene Expression

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9 November 2019

6

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9 November 2019

349-360

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9 November 2019

6

1 reference

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9 November 2019

Tissue-specific and constitutive alpha-tubulin genes of Drosophila melanogaster code for structurally distinct proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism and regulation of eukaryotic protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive and negative regulatory elements mediating transcription from the Drosophila melanogaster actin 5C distal promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein synthesis in Drosophila melanogaster embryos. Two mechanisms for guanine nucleotide exchange on eukaryotic initiation factor 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complementation of adenovirus virus-associated RNA I gene deletion by expression of a mutant eukaryotic translation initiation factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic selection for mutations that reduce or abolish ribosomal recognition of the HIS4 translational initiator region

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vectors for Drosophila P-element-mediated transformation and tissue culture transfection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modified P elements that mimic the P cytotype in Drosophila melanogaster

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical analysis of genetic differences in the growth of Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Truncated protein phosphatase GLC7 restores translational activation of GCN4 expression in yeast mutants defective for the eIF-2 alpha kinase GCN2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and regulation of eukaryotic initiation factor eIF-2. Sequence of the site in the alpha subunit phosphorylated by the haem-controlled repressor and by the double-stranded RNA-activated inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of protein synthesis in insect cells by baculovirus-expressed heme-regulated eIF-2 alpha kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New heat shock puffs and beta-galactosidase activity resulting from transformation of Drosophila with an hsp70-lacZ hybrid gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations at a Zn(II) finger motif in the yeast eIF-2 beta gene alter ribosomal start-site selection during the scanning process.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of mutant eukaryotic initiation factor 2 alpha subunit (eIF-2 alpha) reduces inhibition of guanine nucleotide exchange activity of eIF-2B mediated by eIF-2 alpha phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid changes in gene expression in differentiating tissues of Drosophila.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initiation of protein synthesis in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock effects on phosphorylation of protein synthesis initiation factor proteins eIF-4E and eIF-2 alpha in Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein phosphorylation controls translation rates

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of a mutant form of protein synthesis initiation factor eIF-2 lacking the site of phosphorylation by eIF-2 kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An analysis of vertebrate mRNA sequences: intimations of translational control

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast translation initiation suppressor sui2 encodes the alpha subunit of eukaryotic initiation factor 2 and shares sequence identity with the human alpha subunit.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of the Drosophila melanogaster eIF-2 alpha gene encoding the alpha subunit of translation initiation factor eIF-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A type 1 phosphoprotein phosphatase active with phosphorylated Mr = 68,000 initiation factor 2 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of the eclosion gene cluster and the developmental expression of the Gld gene in Drosophila melanogaster

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms responsible for malignant transformation by regulatory and catalytic domain variants of the interferon-induced enzyme RNA-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translational control in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth-related expression of a double-stranded RNA-dependent protein kinase in 3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of protein synthesis in COS cells transfected with variants of the alpha-subunit of initiation factor eIF-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a phosphorylation-resistant eukaryotic initiation factor 2 alpha-subunit mitigates heat shock inhibition of protein synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9495316

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495316%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495316%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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