(Q47349033)

14 January 2018

title

Influence of fluorescent probe size and cytochrome b5 on drug-drug interactions in CYP2C9. (English)

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Matthew A Hummel

1

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Timothy S Tracy

2

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J Matthew Hutzler

3

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Jan L Wahlstrom

4

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Yihong Zhou

5

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Dan A Rock

6

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publication date

20 February 2006

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Journal of Biomolecular Screening

published in

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volume

11

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issue

3

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page(s)

303-309

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Fluorometric screening for metabolism-based drug--drug interactions

cites work

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https://api.crossref.org/works/10.1177%2F1087057105285612

Atypical Enzyme Kinetics: Their Effect on In Vitro-In Vivo Pharmacokinetic Predictions and Drug Interactions

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057105285612

Generation and Evaluation of a CYP2C9 Heteroactivation Pharmacophore

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057105285612

Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105285612

The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105285612

Topological changes in the CYP3A4 active site probed with phenyldiazene: effect of interaction with NADPH-cytochrome P450 reductase and cytochrome b5 and of site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105285612

The many roles of cytochrome b5

21 January 2018

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https://api.crossref.org/works/10.1177%2F1087057105285612

Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105285612

A new class of CYP2C9 inhibitors: probing 2C9 specificity with high-affinity benzbromarone derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105285612

Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105285612

Stimulation of cytochrome P450 reactions by apo-cytochrome b5: evidence against transfer of heme from cytochrome P450 3A4 to apo-cytochrome b5 or heme oxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105285612

Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105285612

Activation of CYP2C9-mediated metabolism by a series of dapsone analogs: kinetics and structural requirements

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057105285612

21 January 2018

Identifiers

DOI

10.1177/1087057105285612

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14 January 2018

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14 January 2018